ID   C4YUY7_9RICK            Unreviewed;       681 AA.
AC   C4YUY7;
DT   28-JUL-2009, integrated into UniProtKB/TrEMBL.
DT   28-JUL-2009, sequence version 1.
DT   24-JAN-2024, entry version 60.
DE   SubName: Full=Protease 2 {ECO:0000313|EMBL:EER22057.1};
GN   ORFNames=REIS_1259 {ECO:0000313|EMBL:EER22057.1};
OS   Rickettsia endosymbiont of Ixodes scapularis.
OC   Bacteria; Pseudomonadota; Alphaproteobacteria; Rickettsiales;
OC   Rickettsiaceae; Rickettsieae; Rickettsia; spotted fever group.
OX   NCBI_TaxID=444612 {ECO:0000313|EMBL:EER22057.1, ECO:0000313|Proteomes:UP000007035};
RN   [1] {ECO:0000313|Proteomes:UP000007035}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=endosymbiont of Ixodes scapularis
RC   {ECO:0000313|Proteomes:UP000007035};
RA   Joardar V., Hostetler J., Durkin A.S., Gillespie J.J., Williams K.P.,
RA   Daugherty S., Sakamoto J., Shukla M., Ferriera S., Shetty J., Schobel S.,
RA   Steiner S.C., Sobral B.W.S., Hill C.A., Nene V., Caler E.;
RL   Submitted (MAR-2009) to the EMBL/GenBank/DDBJ databases.
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DR   EMBL; CM000770; EER22057.1; -; Genomic_DNA.
DR   RefSeq; WP_008580263.1; NZ_CM000770.1.
DR   AlphaFoldDB; C4YUY7; -.
DR   ESTHER; ricco-PTRB; S9N_PREPL_Peptidase_S9.
DR   MEROPS; S09.010; -.
DR   HOGENOM; CLU_011290_0_1_5; -.
DR   Proteomes; UP000007035; Chromosome.
DR   GO; GO:0004252; F:serine-type endopeptidase activity; IEA:InterPro.
DR   GO; GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
DR   Gene3D; 3.40.50.1820; alpha/beta hydrolase; 1.
DR   Gene3D; 2.130.10.120; Prolyl oligopeptidase, N-terminal domain; 1.
DR   InterPro; IPR029058; AB_hydrolase.
DR   InterPro; IPR023302; Pept_S9A_N.
DR   InterPro; IPR001375; Peptidase_S9.
DR   InterPro; IPR002470; Peptidase_S9A.
DR   PANTHER; PTHR11757:SF19; PROLYL ENDOPEPTIDASE-LIKE; 1.
DR   PANTHER; PTHR11757; PROTEASE FAMILY S9A OLIGOPEPTIDASE; 1.
DR   Pfam; PF00326; Peptidase_S9; 1.
DR   Pfam; PF02897; Peptidase_S9_N; 1.
DR   PRINTS; PR00862; PROLIGOPTASE.
DR   SUPFAM; SSF53474; alpha/beta-Hydrolases; 1.
DR   SUPFAM; SSF50993; Peptidase/esterase 'gauge' domain; 1.
PE   4: Predicted;
KW   Hydrolase {ECO:0000313|EMBL:EER22057.1};
KW   Protease {ECO:0000313|EMBL:EER22057.1}.
FT   DOMAIN          3..407
FT                   /note="Peptidase S9A N-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF02897"
FT   DOMAIN          463..678
FT                   /note="Peptidase S9 prolyl oligopeptidase catalytic"
FT                   /evidence="ECO:0000259|Pfam:PF00326"
SQ   SEQUENCE   681 AA;  79391 MW;  9DBF64A7BB2B6B00 CRC64;
     MKPPITDKQN YSFEVHSATI NDDYHWLRDP KWPNVEDSKI LDYLKAENKY TENFFADLQK
     DKEKIFEELK GRVKLDDESV YVKKKDYYYY HRVEGDKNYP IYCRKHNSVE AHEEIILDVN
     LLAPNGGFTD VAKVAISPDQ NLMAYSVNFT GNEQYNIKIY NLKEQKYLPD NVTDIAPTVI
     WHEQLNGFFY ITINENQRWD KVMFHRLGED VTQDKLIFEV KNPLHFISCE KSASSEYIFI
     NSGDYNENEI YVISMQDVSF TPKLVRAAEN KIFYEIEHNG DYFYIKTNYK AKNFHVIKLL
     VNNFENTSWD DIYIKEEQDK YLKSFDVTNN YLILNYRDQG LPLIKIKRFK DLQENTTHFP
     DESFQASSFS TNFEEDDIRV NYSSLARPNT TYSYDFDSNK LTILKSQEIP SGFNPEEYKV
     ERIFADVKVP ITLFYKKSLF KKDGSNPLYL MGYGAYGISM PVNFRNTAVT LADRGFIYAV
     AHIRGGDDLG HDWYEAAKFL TKKRTFKDFI ACSRALINEQ YTSNNNIVIM GGSAGGMLIG
     YVLNEKPEIY RAAIAHVPFV DVLSTMLDES LPLTLLEYNE WGNPKEKEYF EYIKSYSPYD
     NVKAQNYPAL FVTCGISDPH VGYWEPAKWV AKLRELKTDN NPLLLKINMD KGHKGSAGRF
     DYLKEIADEL VFIFNIFNVG V
//