ID C5A6J1_THEGJ Unreviewed; 440 AA.
AC C5A6J1;
DT 28-JUL-2009, integrated into UniProtKB/TrEMBL.
DT 28-JUL-2009, sequence version 1.
DT 27-MAR-2024, entry version 59.
DE SubName: Full=Peptidase U62, modulator of DNA gyrase, PmbA/TldD protein-like protein (TldD/pmbA) {ECO:0000313|EMBL:ACS33853.1};
GN Name=tldD {ECO:0000313|EMBL:ACS33853.1};
GN OrderedLocusNames=TGAM_1351 {ECO:0000313|EMBL:ACS33853.1};
OS Thermococcus gammatolerans (strain DSM 15229 / JCM 11827 / EJ3).
OC Archaea; Euryarchaeota; Thermococci; Thermococcales; Thermococcaceae;
OC Thermococcus.
OX NCBI_TaxID=593117 {ECO:0000313|EMBL:ACS33853.1, ECO:0000313|Proteomes:UP000001488};
RN [1] {ECO:0000313|EMBL:ACS33853.1, ECO:0000313|Proteomes:UP000001488}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 15229 / JCM 11827 / EJ3
RC {ECO:0000313|Proteomes:UP000001488};
RX PubMed=19558674; DOI=10.1186/gb-2009-10-6-r70;
RA Zivanovic Y., Armengaud J., Lagorce A., Leplat C., Guerin P., Dutertre M.,
RA Anthouard V., Forterre P., Wincker P., Confalonieri F.;
RT "Genome analysis and genome-wide proteomics of Thermococcus gammatolerans,
RT the most radioresistant organism known amongst the Archaea.";
RL Genome Biol. 10:R70.1-R70.23(2007).
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DR EMBL; CP001398; ACS33853.1; -; Genomic_DNA.
DR RefSeq; WP_015858965.1; NC_012804.1.
DR AlphaFoldDB; C5A6J1; -.
DR STRING; 593117.TGAM_1351; -.
DR PaxDb; 593117-TGAM_1351; -.
DR GeneID; 7988410; -.
DR KEGG; tga:TGAM_1351; -.
DR PATRIC; fig|593117.10.peg.1350; -.
DR eggNOG; arCOG00322; Archaea.
DR HOGENOM; CLU_026425_4_1_2; -.
DR OrthoDB; 84520at2157; -.
DR Proteomes; UP000001488; Chromosome.
DR GO; GO:0008237; F:metallopeptidase activity; IEA:InterPro.
DR GO; GO:0006508; P:proteolysis; IEA:InterPro.
DR Gene3D; 3.30.2290.10; PmbA/TldD superfamily; 1.
DR InterPro; IPR045569; Metalloprtase-TldD/E_C.
DR InterPro; IPR045570; Metalloprtase-TldD/E_cen_dom.
DR InterPro; IPR002510; Metalloprtase-TldD/E_N.
DR InterPro; IPR035068; TldD/PmbA_N.
DR InterPro; IPR036059; TldD/PmbA_sf.
DR PANTHER; PTHR43666:SF1; CONSERVED PROTEIN; 1.
DR PANTHER; PTHR43666; TLDD PROTEIN; 1.
DR Pfam; PF01523; PmbA_TldD_1st; 1.
DR Pfam; PF19290; PmbA_TldD_2nd; 1.
DR Pfam; PF19289; PmbA_TldD_3rd; 1.
DR SUPFAM; SSF111283; Putative modulator of DNA gyrase, PmbA/TldD; 1.
PE 4: Predicted;
FT DOMAIN 24..83
FT /note="Metalloprotease TldD/E N-terminal"
FT /evidence="ECO:0000259|Pfam:PF01523"
FT DOMAIN 115..207
FT /note="Metalloprotease TldD/E central"
FT /evidence="ECO:0000259|Pfam:PF19290"
FT DOMAIN 218..436
FT /note="Metalloprotease TldD/E C-terminal"
FT /evidence="ECO:0000259|Pfam:PF19289"
SQ SEQUENCE 440 AA; 49337 MW; 60D73221ABC26D5B CRC64;
MFELNEFILK KAEELGFGDV VVLSYETNRR QVRFANNEIT VAKHWHERKV ELFVEKEKRI
ASTTVTELSE ENVERVLKTL KKNIENLSPK EDYYGIAQGP FKYKDIPETF DKAIVELDEP
NDYVETAINS ALSEGAKRVA GVLYTDHNRL YLTTSNGVEA FDEGTGIEIS VRAFVGDLES
GHGTCSARVL KKFDPELAGR KAGEIAHMAR NPVQGPEGRF DVIFDPLAFA NLLSYMGFML
SAYAAEAGFS FLAGKLGQKV ASELVTLKDV GNLPNGYGSR KFDDEGVPTR ETTVIENGTF
KTFLLNTSLA KKYGTETTAN AGLIMPRPWN LVLEPGDYSK SELFGEVKRG IYITNVWYTR
FQNYVTGDFS TIPRDGIFLL ENNELKPIRN IRVSDNLGRI LSNVVAISNE PFQVHWWEVS
RPVITPYVLV KDVGITRATK
//
