ID C5CE67_KOSOT Unreviewed; 764 AA.
AC C5CE67;
DT 28-JUL-2009, integrated into UniProtKB/TrEMBL.
DT 28-JUL-2009, sequence version 1.
DT 27-MAR-2024, entry version 74.
DE SubName: Full=Diguanylate cyclase and metal dependent phosphohydrolase {ECO:0000313|EMBL:ACR79175.1};
GN OrderedLocusNames=Kole_0452 {ECO:0000313|EMBL:ACR79175.1};
OS Kosmotoga olearia (strain ATCC BAA-1733 / DSM 21960 / TBF 19.5.1).
OC Bacteria; Thermotogota; Thermotogae; Kosmotogales; Kosmotogaceae;
OC Kosmotoga.
OX NCBI_TaxID=521045 {ECO:0000313|EMBL:ACR79175.1, ECO:0000313|Proteomes:UP000002382};
RN [1] {ECO:0000313|EMBL:ACR79175.1, ECO:0000313|Proteomes:UP000002382}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC BAA-1733 / DSM 21960 / TBF 19.5.1
RC {ECO:0000313|Proteomes:UP000002382};
RG US DOE Joint Genome Institute;
RA Lucas S., Copeland A., Lapidus A., Glavina del Rio T., Tice H., Bruce D.,
RA Goodwin L., Pitluck S., Chertkov O., Brettin T., Detter J.C., Han C.,
RA Schmutz J., Larimer F., Land M., Hauser L., Kyrpides N., Ovchinnikova G.,
RA Noll K.;
RT "Complete sequence of Thermotogales bacterium TBF 19.5.1.";
RL Submitted (JUN-2009) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:ACR79175.1, ECO:0000313|Proteomes:UP000002382}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC BAA-1733 / DSM 21960 / TBF 19.5.1
RC {ECO:0000313|Proteomes:UP000002382};
RX PubMed=21914881; DOI=10.1128/JB.05828-11;
RA Swithers K.S., Dipippo J.L., Bruce D.C., Detter C., Tapia R., Han S.,
RA Goodwin L.A., Han J., Woyke T., Pitluck S., Pennacchio L., Nolan M.,
RA Mikhailova N., Land M.L., Nesbo C.L., Gogarten J.P., Noll K.M.;
RT "Genome Sequence of Kosmotoga olearia Strain TBF 19.5.1, a Thermophilic
RT Bacterium with a Wide Growth Temperature Range, Isolated from the Troll B
RT Oil Platform in the North Sea.";
RL J. Bacteriol. 193:5566-5567(2011).
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DR EMBL; CP001634; ACR79175.1; -; Genomic_DNA.
DR RefSeq; WP_012744962.1; NC_012785.1.
DR AlphaFoldDB; C5CE67; -.
DR STRING; 521045.Kole_0452; -.
DR KEGG; kol:Kole_0452; -.
DR eggNOG; COG0834; Bacteria.
DR eggNOG; COG2199; Bacteria.
DR eggNOG; COG2203; Bacteria.
DR eggNOG; COG3437; Bacteria.
DR HOGENOM; CLU_000445_92_5_0; -.
DR OrthoDB; 9804747at2; -.
DR Proteomes; UP000002382; Chromosome.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR CDD; cd01949; GGDEF; 1.
DR CDD; cd00077; HDc; 1.
DR Gene3D; 3.30.450.40; -; 1.
DR Gene3D; 3.30.70.270; -; 1.
DR Gene3D; 1.10.3210.10; Hypothetical protein af1432; 1.
DR Gene3D; 3.30.450.20; PAS domain; 1.
DR Gene3D; 3.40.190.10; Periplasmic binding protein-like II; 1.
DR InterPro; IPR003018; GAF.
DR InterPro; IPR029016; GAF-like_dom_sf.
DR InterPro; IPR000160; GGDEF_dom.
DR InterPro; IPR003607; HD/PDEase_dom.
DR InterPro; IPR037522; HD_GYP_dom.
DR InterPro; IPR029787; Nucleotide_cyclase.
DR InterPro; IPR000014; PAS.
DR InterPro; IPR035965; PAS-like_dom_sf.
DR InterPro; IPR043128; Rev_trsase/Diguanyl_cyclase.
DR InterPro; IPR001638; Solute-binding_3/MltF_N.
DR NCBIfam; TIGR00254; GGDEF; 1.
DR NCBIfam; TIGR00229; sensory_box; 1.
DR PANTHER; PTHR43155:SF2; CYCLIC DI-GMP PHOSPHODIESTERASE PA4108; 1.
DR PANTHER; PTHR43155; CYCLIC DI-GMP PHOSPHODIESTERASE PA4108-RELATED; 1.
DR Pfam; PF13185; GAF_2; 1.
DR Pfam; PF00990; GGDEF; 1.
DR Pfam; PF13487; HD_5; 1.
DR Pfam; PF13426; PAS_9; 1.
DR Pfam; PF00497; SBP_bac_3; 1.
DR SMART; SM00065; GAF; 1.
DR SMART; SM00267; GGDEF; 1.
DR SMART; SM00471; HDc; 1.
DR SMART; SM00091; PAS; 1.
DR SUPFAM; SSF55781; GAF domain-like; 1.
DR SUPFAM; SSF109604; HD-domain/PDEase-like; 1.
DR SUPFAM; SSF55073; Nucleotide cyclase; 1.
DR SUPFAM; SSF53850; Periplasmic binding protein-like II; 1.
DR SUPFAM; SSF55785; PYP-like sensor domain (PAS domain); 1.
DR PROSITE; PS50887; GGDEF; 1.
DR PROSITE; PS51832; HD_GYP; 1.
DR PROSITE; PS50112; PAS; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000002382};
KW Signal {ECO:0000256|ARBA:ARBA00022729};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 77..95
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 127..205
FT /note="PAS"
FT /evidence="ECO:0000259|PROSITE:PS50112"
FT DOMAIN 438..572
FT /note="GGDEF"
FT /evidence="ECO:0000259|PROSITE:PS50887"
FT DOMAIN 560..755
FT /note="HD-GYP"
FT /evidence="ECO:0000259|PROSITE:PS51832"
SQ SEQUENCE 764 AA; 87414 MW; ED342559D5DE7AAA CRC64;
MVPPLELGRP AFFRDTLSVL FTQEYCFATK EGNDQLLSSL NEGLAIIKET GKYKEIYENW
FGTLSAQHLI IKNLTKYGSI ILLILTVGFL LALSWSRVLK IRVEEKTKEL RKELLERMIT
EEKLRVSEER YRKLFESMLD GFILLKPVAD KDGNINNFKI IEANTSFLKA VGKKKEEVVG
KMLWDIFPTV YKSHIKVYEK VIETGRPTHF EIHSDETNKT FEIVGFTPQT GYFAAIVRDI
TQRKQAEKAL KDNLEKIRKL HEIALKMEKS KSEEEVYHLI VEAAKKILEF DIYSLDIVEG
NKFVVKAISE KVASPEIMEA PLNEGIAGKT FRTGKTIVVK DIANEPEAKP RSKEYRSAIS
IPIGNIGVFQ TISTKRNAFS KEDVELAELL IFHATEAIER IRSEAKIKYL IFHDHLTGVY
NRAFFEEELK RFDAESHLPL SIIMGDVNGL KLVNDAFGHT EGDRLLKTVA TSIISSCRPQ
DIVARWGGDE FIILLPRAGY MLAEGILKRI KMNLEKSDEG SYIPISVAFG IATKENANQN
IQEILKKVEE QMYKNKLLKS MSTRNSIITS LEKMLLEKSN ETEEHARRMR KIAYEFGKYI
NLTDSEINDL VLLAALHDIG KISVPESILK KPGPLTVEEW EKIKEHPETG YRIAINSPDL
VTIADGILYH HEWWNGSGYP RGLKEEEIPF IARVISIIDA YDVMTSGRPY KKRLSKDKAL
EEIKKSSGIQ FDPRLARLFM EFMQSLEDSE KSDRNSDKDK SYHE
//
