ID C5CXL3_VARPS Unreviewed; 275 AA.
AC C5CXL3;
DT 28-JUL-2009, integrated into UniProtKB/TrEMBL.
DT 28-JUL-2009, sequence version 1.
DT 27-MAR-2024, entry version 67.
DE SubName: Full=Enoyl-CoA hydratase/isomerase {ECO:0000313|EMBL:ACS18869.1};
GN OrderedLocusNames=Vapar_2234 {ECO:0000313|EMBL:ACS18869.1};
OS Variovorax paradoxus (strain S110).
OC Bacteria; Pseudomonadota; Betaproteobacteria; Burkholderiales;
OC Comamonadaceae; Variovorax.
OX NCBI_TaxID=543728 {ECO:0000313|EMBL:ACS18869.1};
RN [1] {ECO:0000313|EMBL:ACS18869.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=S110 {ECO:0000313|EMBL:ACS18869.1};
RG US DOE Joint Genome Institute;
RA Lucas S., Copeland A., Lapidus A., Glavina del Rio T., Tice H., Bruce D.,
RA Goodwin L., Pitluck S., Chertkov O., Brettin T., Detter J.C., Han C.,
RA Larimer F., Land M., Hauser L., Kyrpides N., Ovchinnikova G., Orwin P.,
RA Leadbetter J.R., Spain J.C., Han J.I.;
RT "Complete sequence of chromosome 1 of Variovorax paradoxus S110.";
RL Submitted (JUN-2009) to the EMBL/GenBank/DDBJ databases.
CC -!- PATHWAY: Lipid metabolism; fatty acid beta-oxidation.
CC {ECO:0000256|ARBA:ARBA00005005}.
CC -!- SIMILARITY: Belongs to the enoyl-CoA hydratase/isomerase family.
CC {ECO:0000256|ARBA:ARBA00005254, ECO:0000256|RuleBase:RU003707}.
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DR EMBL; CP001635; ACS18869.1; -; Genomic_DNA.
DR AlphaFoldDB; C5CXL3; -.
DR STRING; 543728.Vapar_2234; -.
DR KEGG; vap:Vapar_2234; -.
DR eggNOG; COG1024; Bacteria.
DR HOGENOM; CLU_009834_7_0_4; -.
DR OrthoDB; 4608673at2; -.
DR UniPathway; UPA00659; -.
DR GO; GO:0016853; F:isomerase activity; IEA:UniProtKB-KW.
DR GO; GO:0006635; P:fatty acid beta-oxidation; IEA:UniProtKB-UniPathway.
DR CDD; cd06558; crotonase-like; 1.
DR Gene3D; 1.10.12.10; Lyase 2-enoyl-coa Hydratase, Chain A, domain 2; 1.
DR InterPro; IPR029045; ClpP/crotonase-like_dom_sf.
DR InterPro; IPR045002; Ech1-like.
DR InterPro; IPR018376; Enoyl-CoA_hyd/isom_CS.
DR InterPro; IPR001753; Enoyl-CoA_hydra/iso.
DR InterPro; IPR014748; Enoyl-CoA_hydra_C.
DR PANTHER; PTHR43149:SF1; DELTA(3,5)-DELTA(2,4)-DIENOYL-COA ISOMERASE, MITOCHONDRIAL; 1.
DR PANTHER; PTHR43149; ENOYL-COA HYDRATASE; 1.
DR Pfam; PF00378; ECH_1; 1.
DR SUPFAM; SSF52096; ClpP/crotonase; 1.
DR PROSITE; PS00166; ENOYL_COA_HYDRATASE; 1.
PE 3: Inferred from homology;
KW Fatty acid metabolism {ECO:0000256|ARBA:ARBA00022832};
KW Isomerase {ECO:0000256|ARBA:ARBA00023235, ECO:0000313|EMBL:ACS18869.1};
KW Lipid metabolism {ECO:0000256|ARBA:ARBA00023098}.
SQ SEQUENCE 275 AA; 28713 MW; 2749B9A90E02156D CRC64;
MAERIEWTRH PDGVVQLLLA RADKMNALDP AMFDALIEAG EALRGDAAVR AVVISGQGKA
FCAGLDMASF ERMGQGAASA VLGAAAGGTD LSARTHGISN AAQYVAMAWR EVPVPVIAAV
HGVAFGGGLQ VALGADIRIV APDTRLSVME IKWGLVPDMG GMVLMRELAR SDIVRELTFT
GRIFSGEEAL QLGFATRLAA DPLAEALQMA HGIAGKSPDA IRAGKRLLNA ALSHSAADLL
IAESVEQQAL IGSANQKEAV QANIERRPPR FGSSA
//
