ID C5DB74_VITVI Unreviewed; 424 AA.
AC C5DB74;
DT 28-JUL-2009, integrated into UniProtKB/TrEMBL.
DT 28-JUL-2009, sequence version 1.
DT 24-JAN-2024, entry version 58.
DE RecName: Full=ethanolamine-phosphate cytidylyltransferase {ECO:0000256|ARBA:ARBA00024221};
DE EC=2.7.7.14 {ECO:0000256|ARBA:ARBA00024221};
DE AltName: Full=CTP:phosphoethanolamine cytidylyltransferase {ECO:0000256|ARBA:ARBA00031473};
GN ORFNames=40N03_220 {ECO:0000313|EMBL:CAQ58636.1};
OS Vitis vinifera (Grape).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; Vitales; Vitaceae; Viteae; Vitis.
OX NCBI_TaxID=29760 {ECO:0000313|EMBL:CAQ58636.1};
RN [1] {ECO:0000313|EMBL:CAQ58636.1}
RP NUCLEOTIDE SEQUENCE.
RC TISSUE=Leaves {ECO:0000313|EMBL:CAQ58636.1};
RA Genoscope - CEA;
RL Submitted (JUN-2008) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:CAQ58636.1}
RP NUCLEOTIDE SEQUENCE.
RC TISSUE=Leaves {ECO:0000313|EMBL:CAQ58636.1};
RA Chopin F., Bruyere C., Buisine N., Dossat C., Choisne N., Tassin J.,
RA Lemainque A., Segurens B., Policriti A., Morgante M., Ratnaparkhe MR.,
RA Aubourg A., Wincker P., Caboche M., Weissenbach J., Adam-Blondon AF.;
RT "The grapevine high level of heterozygocity is mainly due to small
RT insertion/deletion events.";
RL Submitted (JUN-2009) to the EMBL/GenBank/DDBJ databases.
CC -!- PATHWAY: Lipid metabolism. {ECO:0000256|ARBA:ARBA00005189}.
CC -!- PATHWAY: Phospholipid metabolism; phosphatidylethanolamine
CC biosynthesis; phosphatidylethanolamine from ethanolamine: step 2/3.
CC {ECO:0000256|ARBA:ARBA00024191}.
CC -!- SIMILARITY: Belongs to the cytidylyltransferase family.
CC {ECO:0000256|ARBA:ARBA00010101}.
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DR EMBL; CU914151; CAQ58636.1; -; Genomic_DNA.
DR AlphaFoldDB; C5DB74; -.
DR UniPathway; UPA00558; UER00742.
DR ExpressionAtlas; C5DB74; baseline and differential.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0004306; F:ethanolamine-phosphate cytidylyltransferase activity; IEA:UniProtKB-EC.
DR GO; GO:0006646; P:phosphatidylethanolamine biosynthetic process; IEA:UniProtKB-UniPathway.
DR CDD; cd02174; CCT; 1.
DR CDD; cd02173; ECT; 1.
DR Gene3D; 3.40.50.620; HUPs; 2.
DR InterPro; IPR041723; CCT.
DR InterPro; IPR004821; Cyt_trans-like.
DR InterPro; IPR044608; Ect1/PCYT2.
DR InterPro; IPR014729; Rossmann-like_a/b/a_fold.
DR NCBIfam; TIGR00125; cyt_tran_rel; 2.
DR PANTHER; PTHR45780; ETHANOLAMINE-PHOSPHATE CYTIDYLYLTRANSFERASE; 1.
DR PANTHER; PTHR45780:SF2; ETHANOLAMINE-PHOSPHATE CYTIDYLYLTRANSFERASE; 1.
DR Pfam; PF01467; CTP_transf_like; 2.
DR SUPFAM; SSF52374; Nucleotidylyl transferase; 2.
PE 3: Inferred from homology;
KW Lipid biosynthesis {ECO:0000256|ARBA:ARBA00022516};
KW Lipid metabolism {ECO:0000256|ARBA:ARBA00023098};
KW Membrane {ECO:0000256|SAM:Phobius};
KW Nucleotidyltransferase {ECO:0000256|ARBA:ARBA00022695,
KW ECO:0000313|EMBL:CAQ58636.1};
KW Phospholipid biosynthesis {ECO:0000256|ARBA:ARBA00023209};
KW Phospholipid metabolism {ECO:0000256|ARBA:ARBA00023264};
KW Transferase {ECO:0000256|ARBA:ARBA00022679, ECO:0000313|EMBL:CAQ58636.1};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 19..41
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 59..188
FT /note="Cytidyltransferase-like"
FT /evidence="ECO:0000259|Pfam:PF01467"
FT DOMAIN 261..351
FT /note="Cytidyltransferase-like"
FT /evidence="ECO:0000259|Pfam:PF01467"
FT REGION 205..225
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 424 AA; 47331 MW; B9E2F6A260C09BDD CRC64;
MIMGFDLGHS SDSIQSSKLL ATCLIGGVVL GVSVLGFYLA FPPPRQLSWR RKKKPIRVYM
DGCFDMMHYG HCNALRQARA LGDQLVVGVV SDAEITANKG PPVTPLNERM IMVSGVKWVD
EVIPDAPYAI TEDFMKKLFD EYNIDYIIHG DDPCILPDGT DAYALAKKAG RYKQIKRTEG
VSSTDIVGRM LLCVRERSLS DSHNHSSLQR QFSHGHSQKF EDGGSGSGTR ISHFLPSGQF
LTIHLFLFWL QGPGPDARIV YIDGAFDLFH AGHVEILKLA RGLGDFLLVG IHTDQTVSAN
RGAHRPIMNL HERSLSVLAC RYVDEVIIGA PWEVSKDMIT TFNISLVVHG TVAEYNNFPK
GKEDPYAIPI SLGIYEQLES PLDITTTTII RRIVSNHEAY QKRNEKKAES EKRYYEDKTF
VSGD
//
