ID   C5DC12_LACTC            Unreviewed;       868 AA.
AC   C5DC12;
DT   28-JUL-2009, integrated into UniProtKB/TrEMBL.
DT   28-JUL-2009, sequence version 1.
DT   27-MAR-2024, entry version 60.
DE   SubName: Full=KLTH0A06974p {ECO:0000313|EMBL:CAR21319.1};
GN   OrderedLocusNames=KLTH0A06974g {ECO:0000313|EMBL:CAR21319.1};
OS   Lachancea thermotolerans (strain ATCC 56472 / CBS 6340 / NRRL Y-8284)
OS   (Yeast) (Kluyveromyces thermotolerans).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC   Saccharomycetales; Saccharomycetaceae; Lachancea.
OX   NCBI_TaxID=559295 {ECO:0000313|EMBL:CAR21319.1, ECO:0000313|Proteomes:UP000002036};
RN   [1] {ECO:0000313|EMBL:CAR21319.1, ECO:0000313|Proteomes:UP000002036}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 56472 / CBS 6340 / NRRL Y-8284
RC   {ECO:0000313|Proteomes:UP000002036};
RX   PubMed=19525356; DOI=10.1101/gr.091546.109;
RG   The Genolevures Consortium;
RA   Souciet J.-L., Dujon B., Gaillardin C., Johnston M., Baret P.V.,
RA   Cliften P., Sherman D.J., Weissenbach J., Westhof E., Wincker P., Jubin C.,
RA   Poulain J., Barbe V., Segurens B., Artiguenave F., Anthouard V.,
RA   Vacherie B., Val M.-E., Fulton R.S., Minx P., Wilson R., Durrens P.,
RA   Jean G., Marck C., Martin T., Nikolski M., Rolland T., Seret M.-L.,
RA   Casaregola S., Despons L., Fairhead C., Fischer G., Lafontaine I., Leh V.,
RA   Lemaire M., de Montigny J., Neuveglise C., Thierry A., Blanc-Lenfle I.,
RA   Bleykasten C., Diffels J., Fritsch E., Frangeul L., Goeffon A.,
RA   Jauniaux N., Kachouri-Lafond R., Payen C., Potier S., Pribylova L.,
RA   Ozanne C., Richard G.-F., Sacerdot C., Straub M.-L., Talla E.;
RT   "Comparative genomics of protoploid Saccharomycetaceae.";
RL   Genome Res. 19:1696-1709(2009).
CC   -!- SUBCELLULAR LOCATION: Cytoplasm, P-body
CC       {ECO:0000256|ARBA:ARBA00004201}.
CC   -!- SIMILARITY: Belongs to the PAT1 family.
CC       {ECO:0000256|ARBA:ARBA00009138}.
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DR   EMBL; CU928165; CAR21319.1; -; Genomic_DNA.
DR   RefSeq; XP_002551761.1; XM_002551715.1.
DR   AlphaFoldDB; C5DC12; -.
DR   STRING; 559295.C5DC12; -.
DR   GeneID; 8290568; -.
DR   KEGG; lth:KLTH0A06974g; -.
DR   eggNOG; KOG4592; Eukaryota.
DR   HOGENOM; CLU_012622_1_0_1; -.
DR   InParanoid; C5DC12; -.
DR   OMA; YLEHSGH; -.
DR   OrthoDB; 2786412at2759; -.
DR   Proteomes; UP000002036; Chromosome A.
DR   GO; GO:0000932; C:P-body; IEA:UniProtKB-SubCell.
DR   GO; GO:0000290; P:deadenylation-dependent decapping of nuclear-transcribed mRNA; IEA:InterPro.
DR   InterPro; IPR039900; Pat1-like.
DR   InterPro; IPR019167; PAT1_dom.
DR   PANTHER; PTHR21551:SF0; PROTEIN ASSOCIATED WITH TOPO II RELATED-1, ISOFORM A; 1.
DR   PANTHER; PTHR21551; TOPOISOMERASE II-ASSOCIATED PROTEIN PAT1; 1.
DR   Pfam; PF09770; PAT1; 1.
PE   3: Inferred from homology;
KW   Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW   Reference proteome {ECO:0000313|Proteomes:UP000002036}.
FT   DOMAIN          1..857
FT                   /note="mRNA decay factor PAT1"
FT                   /evidence="ECO:0000259|Pfam:PF09770"
FT   REGION          1..33
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          294..347
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          474..498
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        297..324
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        325..347
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   868 AA;  95897 MW;  57CE7FB26A0A6738 CRC64;
     MSFFGFDSSL PNQGKGGGRE KRTATPDKPL DFDETYQGLG EYQNEEDDYL NNETFGNATD
     LGTDFDFGYG KGELSSNSAP SAAQVDHGRS YASAATTGPV VTNPGYVAAA PHSMDEGMDF
     TPMESLWTNQ PMMMQHPQQP QHPQVLSMEE LERQQQQQQI GVPHGQQQGY MGMPPMPPMG
     YGYAPQAFMP QAQVMPGAAY PSAPQGMPPQ GLPLPPQGMP PQSMPPPGMV PPQYQQHAMA
     MQQQPGAHQQ AVQQVPSVVS PLAQQELQQS PHLVPKAALP ASAGVVSDFA TPSPPHLAAS
     KSASGQARLA SPSQMAPSSQ DSRESTPRGT RRGSMRKHQE PLSQDDFKRL QVRQAKVDKI
     LRHSGVMTPR DKDFITRYQL SQIVTDDPYN EDFYFQVYKI IQRGGIVGES NKGLIARAYL
     EHSGHRLGGR YKRADVALQR MQSQVEKAVT VAKERPQKNR ENFDGAKEGV LGKISSAKNS
     KAPRRQLQIP QQRDEDEDLG TSAIEDVVES LNGVDISSSS RARRRSSYAF RSVDQRAVLS
     RSGGRKFVLS LIETVYAEVL DLEALLRSGK ETDSTHLWES LHIADDAYEV SPFISILSFD
     KGVKIMPRIF NFLNKEQKLK LLYCFFSELS HLNIIVTSSY KTNPDPSDSQ LKKIELFQSV
     FLKIIVSFLS SSAEFLEVLG LLLALVKNNN VSFISTSKIG LNLVTVLISR AALIKQDVSR
     GSVLSSVEAS SWNEIYDKLF TALETKLAAV FPPEEYTSKV VATSSNGTPT SATVGQSSGH
     QFYDQSYIWQ FLASLALSGK LNHQRVIIDE IREEIFGTIS RAEQLVKNVP VEEQQIALYQ
     RDKLYQDLNL FLNVMGLVAR DGEISELK
//