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Database: UniProt
Entry: C5DDL8_LACTC
LinkDB: C5DDL8_LACTC
Original site: C5DDL8_LACTC 
ID   C5DDL8_LACTC            Unreviewed;      2005 AA.
AC   C5DDL8;
DT   28-JUL-2009, integrated into UniProtKB/TrEMBL.
DT   28-JUL-2009, sequence version 1.
DT   27-SEP-2017, entry version 60.
DE   SubName: Full=KLTH0C02046p {ECO:0000313|EMBL:CAR21879.1};
GN   OrderedLocusNames=KLTH0C02046g {ECO:0000313|EMBL:CAR21879.1};
OS   Lachancea thermotolerans (strain ATCC 56472 / CBS 6340 / NRRL Y-8284)
OS   (Yeast) (Kluyveromyces thermotolerans).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina;
OC   Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Lachancea.
OX   NCBI_TaxID=559295 {ECO:0000313|EMBL:CAR21879.1, ECO:0000313|Proteomes:UP000002036};
RN   [1] {ECO:0000313|EMBL:CAR21879.1, ECO:0000313|Proteomes:UP000002036}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 56472 / CBS 6340 / NRRL Y-8284
RC   {ECO:0000313|Proteomes:UP000002036};
RX   PubMed=19525356; DOI=10.1101/gr.091546.109;
RG   The Genolevures Consortium;
RA   Souciet J.-L., Dujon B., Gaillardin C., Johnston M., Baret P.V.,
RA   Cliften P., Sherman D.J., Weissenbach J., Westhof E., Wincker P.,
RA   Jubin C., Poulain J., Barbe V., Segurens B., Artiguenave F.,
RA   Anthouard V., Vacherie B., Val M.-E., Fulton R.S., Minx P., Wilson R.,
RA   Durrens P., Jean G., Marck C., Martin T., Nikolski M., Rolland T.,
RA   Seret M.-L., Casaregola S., Despons L., Fairhead C., Fischer G.,
RA   Lafontaine I., Leh V., Lemaire M., de Montigny J., Neuveglise C.,
RA   Thierry A., Blanc-Lenfle I., Bleykasten C., Diffels J., Fritsch E.,
RA   Frangeul L., Goeffon A., Jauniaux N., Kachouri-Lafond R., Payen C.,
RA   Potier S., Pribylova L., Ozanne C., Richard G.-F., Sacerdot C.,
RA   Straub M.-L., Talla E.;
RT   "Comparative genomics of protoploid Saccharomycetaceae.";
RL   Genome Res. 19:1696-1709(2009).
CC   -!- CAUTION: Lacks conserved residue(s) required for the propagation
CC       of feature annotation. {ECO:0000256|PROSITE-ProRule:PRU00448}.
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DR   EMBL; CU928167; CAR21879.1; -; Genomic_DNA.
DR   RefSeq; XP_002552317.1; XM_002552271.1.
DR   STRING; 381046.XP_002552317.1; -.
DR   EnsemblFungi; CAR21879; CAR21879; KLTH0C02046g.
DR   GeneID; 8291176; -.
DR   KEGG; lth:KLTH0C02046g; -.
DR   HOGENOM; HOG000111448; -.
DR   InParanoid; C5DDL8; -.
DR   KO; K21864; -.
DR   OrthoDB; EOG092C00XX; -.
DR   Proteomes; UP000002036; Chromosome C.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:EnsemblFungi.
DR   GO; GO:0005262; F:calcium channel activity; IEA:EnsemblFungi.
DR   GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR   InterPro; IPR002048; EF_hand_dom.
DR   InterPro; IPR005821; Ion_trans_dom.
DR   Pfam; PF00520; Ion_trans; 4.
DR   PROSITE; PS50222; EF_HAND_2; 1.
PE   4: Predicted;
KW   Complete proteome {ECO:0000313|Proteomes:UP000002036};
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000002036};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    299    317       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    337    358       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    509    528       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    640    668       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    853    872       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    922    949       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM   1159   1181       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM   1193   1211       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM   1292   1314       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM   1402   1424       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM   1480   1503       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM   1515   1533       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM   1545   1562       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM   1609   1631       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM   1695   1720       Helical. {ECO:0000256|SAM:Phobius}.
FT   DOMAIN     1740   1775       EF-hand. {ECO:0000259|PROSITE:PS50222}.
SQ   SEQUENCE   2005 AA;  228866 MW;  E2D8A2506EE5F0BC CRC64;
     MASRRNLTHR QPPMEHETSV EPNQTPVIVK IDEADTVTEG EGGVLNLNPA GGSKHQENTK
     NLRRPNLTVI TRNSDSSFDR SQLSATSIKS HFRNFISPTR TEQSDTEGSG SADEGPISYT
     SALSDEDNLR SAAVISTIDE GDLSDFKDLQ DEFKNAMKEG NSTWLPKSRR NSKVPDAETQ
     EAPRREPHLS LEPPREHDRS SSASPLRAAS SLGIQLTRDS SNGKNPSKYT NRIFSDAGGY
     DHDADSDWSE EESAQGSSNR PQREEPSKPP LLLFGNSMGL ISPNNPIRRK LAALLLKKWA
     PLPNLAFLVA MVATLALSHI NNSGDFTYDS TGIDSLLLVA NAFFTIEILA KIVAFGFWDD
     SQLFHARGEK YKTVYQTLGL AKFFHNLEAK YGSEFMKKIF PFDIDDTSAT KEIRDKQLRS
     SVTFNGAPRS YNTEIPLHRA FARSSWNRID LLSTVCLWIS LSLTINEYDF KHGIRIFKAI
     GVLRVLKLAA IQDRQSDILR SLKYGLPQLL NVGFMLLYFW VFFGILGVQS FRGSLRRQCV
     WTNPNDTTET YVNEMQFCGG YLESVTKNKK PYIFSDGKEG PIAKGFLCPQ NSKCISDTNP
     YNGRVSFDNI LTSMELVFVT ISANTFTDIM YYTMDSDSMA ASIFFVFCIF SLNIWMINLL
     IAVLVSSFEK ANELVRKKGQ KNIVPSAFQR IRKSTFDYIK KKARSKRLSP RAELWLKWYK
     RFEFLFVSLI FAELIMQATV TSRSSSNHIE HVLKFDQATA FVLLFESVLR LVIHSDNIWK
     FLINPAYVFD LLNSIFSTII TLPNARRKLG QNYYWLNLIQ VVRFYRVITE ISVTRNLWKQ
     VLGNVLLIWD LTGFYFLFLF LVSIVISVYF DGVIPISQID ETPFGMYSVT NTFLTLFTIG
     STENWTDALY ALQENLPNKS SQFFGVVLLI MWFFMANFVM LNIFIAIIAE SLDVKEEEKR
     PLQIKHYLKH VYPQKIRDFA SASLMGRIKN KIFGNSGYDD SKDFRQFLFR GTAIVSIAQQ
     YNILEDSPQD TTTKEGVPYF IKNIKRILNN YSVLKLFANN PFYKKPEVVY VETVDSVGLN
     KKFTLKLNEF EEEKLRYLKE HPMYNNSYFI FPPNHILRKF CQSLTTPCVG KRTDGFRFFG
     DNTNTYDRNS YFKHIKKDVF VGFISIATIL MVVYSCSLTP LYRINHASGV NKWSMISDAI
     FVTIFSLEFL IKTVADGVIH TPNAYLRNPW NCIDVIVLLS LWIDFVSGLK RDDDLSRVFR
     GLTALRALRC LTISKTARST FDQVLFDGIR KIIGAAMVSL TLLFPFAVWG LGLFRGRFGV
     CNDGVDLSQC YNEFSNQVFD FEILTPRVYS QPYLYMNSFS TAFRSLYEIV SLEGWVDMLS
     NSMASTGIGT VPETFASPGN GAFFVLFNFL SMVFILTLFI SFIIRNHART TGSAFYTIEE
     KSWLEVKKLL SQARPEPTPD VLSMSKFRSF VYRLAVEKTY FWYAFFLQAV LYLHIITLLL
     YAYHEANGLG TYQDVIFIIS SSVFLMQEGL YIFGKGVRLW FAKKWDVFKF FVVVMSFGLN
     VAQTRMDGIV LGFTNVRDLF QLAIFLFVIQ QNDILSELIN TAMASLPSIL SLTYTWGILF
     LVYAIALNQI FGLTKLGPNT TGNINFRTVI KSLIVLFRCS FGEGWNYIMD DLTVKSPFCY
     VDKTSGRTDC GSKPYAYVLL MSWNILSMYI FLNMFVSLIL ESFSYLYHAG SGSKSVASRD
     EIRKFRNAWR KFDPDGVGEI ETNLLPRFMH SFDGLLSYKI WEGRLSVSNL VKNYMKVNPS
     DPYDVEVDLV GLNKELESID RKKIIERKTQ YRRFIQEARH LSAFNNGVKF SKIVQQIPLY
     TAYNPQECLG IDEFVKRLYV MGKVDRFLEN ERNVDVLEMV VTRWKFLSER RILRSKAAGG
     FRNTPQPRNI LDLALTSSDH PDTPKLNFSV SNFNWSPRRR GSDQGGHLLD TNSLSPEQDG
     ENTESDSGGS SKSSDSQSHK RGLIP
//
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