ID   C5DGS0_LACTC            Unreviewed;      1279 AA.
AC   C5DGS0;
DT   28-JUL-2009, integrated into UniProtKB/TrEMBL.
DT   28-JUL-2009, sequence version 1.
DT   27-MAR-2024, entry version 78.
DE   SubName: Full=KLTH0D07590p {ECO:0000313|EMBL:CAR22612.1};
GN   OrderedLocusNames=KLTH0D07590g {ECO:0000313|EMBL:CAR22612.1};
OS   Lachancea thermotolerans (strain ATCC 56472 / CBS 6340 / NRRL Y-8284)
OS   (Yeast) (Kluyveromyces thermotolerans).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC   Saccharomycetales; Saccharomycetaceae; Lachancea.
OX   NCBI_TaxID=559295 {ECO:0000313|EMBL:CAR22612.1, ECO:0000313|Proteomes:UP000002036};
RN   [1] {ECO:0000313|EMBL:CAR22612.1, ECO:0000313|Proteomes:UP000002036}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 56472 / CBS 6340 / NRRL Y-8284
RC   {ECO:0000313|Proteomes:UP000002036};
RX   PubMed=19525356; DOI=10.1101/gr.091546.109;
RG   The Genolevures Consortium;
RA   Souciet J.-L., Dujon B., Gaillardin C., Johnston M., Baret P.V.,
RA   Cliften P., Sherman D.J., Weissenbach J., Westhof E., Wincker P., Jubin C.,
RA   Poulain J., Barbe V., Segurens B., Artiguenave F., Anthouard V.,
RA   Vacherie B., Val M.-E., Fulton R.S., Minx P., Wilson R., Durrens P.,
RA   Jean G., Marck C., Martin T., Nikolski M., Rolland T., Seret M.-L.,
RA   Casaregola S., Despons L., Fairhead C., Fischer G., Lafontaine I., Leh V.,
RA   Lemaire M., de Montigny J., Neuveglise C., Thierry A., Blanc-Lenfle I.,
RA   Bleykasten C., Diffels J., Fritsch E., Frangeul L., Goeffon A.,
RA   Jauniaux N., Kachouri-Lafond R., Payen C., Potier S., Pribylova L.,
RA   Ozanne C., Richard G.-F., Sacerdot C., Straub M.-L., Talla E.;
RT   "Comparative genomics of protoploid Saccharomycetaceae.";
RL   Genome Res. 19:1696-1709(2009).
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; CU928168; CAR22612.1; -; Genomic_DNA.
DR   RefSeq; XP_002553050.1; XM_002553004.1.
DR   AlphaFoldDB; C5DGS0; -.
DR   STRING; 559295.C5DGS0; -.
DR   GeneID; 8295284; -.
DR   KEGG; lth:KLTH0D07590g; -.
DR   eggNOG; KOG1839; Eukaryota.
DR   HOGENOM; CLU_003256_2_0_1; -.
DR   InParanoid; C5DGS0; -.
DR   OMA; HPVWDKD; -.
DR   OrthoDB; 927222at2759; -.
DR   Proteomes; UP000002036; Chromosome D.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR   GO; GO:0006996; P:organelle organization; IEA:InterPro.
DR   CDD; cd15466; CLU-central; 1.
DR   Gene3D; 1.25.40.10; Tetratricopeptide repeat domain; 2.
DR   InterPro; IPR033646; CLU-central.
DR   InterPro; IPR025697; CLU_dom.
DR   InterPro; IPR028275; CLU_N.
DR   InterPro; IPR027523; CLU_prot.
DR   InterPro; IPR023231; GSKIP_dom_sf.
DR   InterPro; IPR011990; TPR-like_helical_dom_sf.
DR   PANTHER; PTHR12601:SF6; CLUSTERED MITOCHONDRIA PROTEIN HOMOLOG; 1.
DR   PANTHER; PTHR12601; EUKARYOTIC TRANSLATION INITIATION FACTOR 3 SUBUNIT EIF-3; 1.
DR   Pfam; PF13236; CLU; 1.
DR   Pfam; PF15044; CLU_N; 1.
DR   Pfam; PF12807; eIF3_p135; 1.
DR   Pfam; PF13374; TPR_10; 1.
DR   SUPFAM; SSF103107; Hypothetical protein c14orf129, hspc210; 1.
DR   SUPFAM; SSF48452; TPR-like; 1.
DR   PROSITE; PS51823; CLU; 1.
PE   4: Predicted;
KW   Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW   Reference proteome {ECO:0000313|Proteomes:UP000002036}.
FT   DOMAIN          350..606
FT                   /note="Clu"
FT                   /evidence="ECO:0000259|PROSITE:PS51823"
FT   REGION          176..201
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          1220..1279
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        1220..1237
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        1238..1252
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   1279 AA;  143558 MW;  041D58D7B514A72A CRC64;
     MRSARLLPLG FQDHNFKELT KFKSCKKFTF FESSSKSSTK SRNLTEYLTT MDAQATDAVT
     VSVRLPHQKQ EVQLNLVKSS SVQVVADILQ FSPSSRCLTN LELFQKSQKL TGDEILKNLS
     NSDSLKLDVK FKPYTARDAL RHVTLVRDTI GFTSETQDGI SDFAISTGSQ ISSMPLRPIK
     SSPPLKGANG ESSAFEISEE EKKDLQQTVR DSLSKRQTVN EILKAKSGII TPCLRSLALS
     AYNPVPPFYR TKGHLLYLHV ITLENEAFHV TATSSGFYVN KSTSTKFDPS PRSEGEVPKV
     SLLDLFSTHS KKFKDHLSKL EKKVSSLDSV FTARPSTTFL GKPWLVSTTP SGAGHHSRLQ
     LSEADFNTER NFNDEFQAIK DMTSSDFQSI VDTEKLTAKV YQEFTETAVK DAMSIFYDDL
     VPMNPEAPSR EHIYLKNNIF YAFVGDVNGN YTKVGGDAAA FAASNQDLQA VKLLHRVSLS
     EIHYLLCVII DFAGRRVLAQ TPVPGLLSAM GSVNKKNPET DEIITEDLVS DVNVVYGLDE
     ATGEVLFDEE FDEALESFSK VFHLKNHEAG SAKIKFSSNS KGIVGSDKRK YVLDLANSHP
     LDSQFARKYY DNVPESQRYP HRQTLVRNEL VDKWWASKLE GSDLTFEKAF DEKLFAFNPD
     AYIREGVEDP LVEEVSSYLT NEVLPSFAKD YAIGNLTAPY DGDHLTDSMH KNGINMRYLG
     KLIELAENEL KDQVVQHQSK TSEVAASNEE HKKWEKDYLI KIEKLIKERQ AKINKLVQEG
     KDIPEDLKGN LKLDEKDIRK PTKGKAAIVN KDQLTCLIKV SQLEIAARSL KHVLREYTKD
     LPIPVLPSVV VYFFNLLFGS SFNETPEVEI VDSFYAGKSF SFAKLSRQGL LKEICNQAQR
     RFIYTLPNDV VEEFCSGAFP LIRAISKKFG IQFLNKEYFF TQEQFEKFLQ SQDKKTKSKI
     EVPKATFSVN DLVLIPIVKD GDYRSLTGDN FWNQGAAILN EKEADGLVLL SQALTIKEEV
     NGVIHHSVAE SYMAMSTIYH TLKRIPEALT YCRKACAIYE RTCGVDSFEV LRCLTNLAIL
     EISNKCPSNG ALVLQRIMNT LDALCVAIHP AVINAYTMLQ QASLASKEPK LAIEVMKKLS
     ETILQIEDGE RTIAYGYNQS RLGDLYATLN DLNGSLKAIT EAREVFQREL GLNDETTAQC
     NQWVTSIEAL MESQLQQRKL TQQQSTVNSS GTAANRKQKP SKKQEEPNPE LANKSVDELL
     SFIEGTKPKN SKGKKKNKK
//