ID C5DPQ5_ZYGRC Unreviewed; 1548 AA.
AC C5DPQ5;
DT 28-JUL-2009, integrated into UniProtKB/TrEMBL.
DT 28-JUL-2009, sequence version 1.
DT 27-MAR-2024, entry version 80.
DE SubName: Full=ZYRO0A05258p {ECO:0000313|EMBL:CAR25666.1};
GN OrderedLocusNames=ZYRO0A05258g {ECO:0000313|EMBL:CAR25666.1};
OS Zygosaccharomyces rouxii (strain ATCC 2623 / CBS 732 / NBRC 1130 / NCYC 568
OS / NRRL Y-229) (Candida mogii).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC Saccharomycetales; Saccharomycetaceae; Zygosaccharomyces.
OX NCBI_TaxID=559307 {ECO:0000313|EMBL:CAR25666.1, ECO:0000313|Proteomes:UP000008536};
RN [1] {ECO:0000313|Proteomes:UP000008536}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 2623 / CBS 732 / BCRC 21506 / NBRC 1130 / NCYC 568 / NRRL
RC Y-229 {ECO:0000313|Proteomes:UP000008536};
RX PubMed=19525356; DOI=10.1101/gr.091546.109;
RG The Genolevures Consortium;
RA Souciet J.-L., Dujon B., Gaillardin C., Johnston M., Baret P.V.,
RA Cliften P., Sherman D.J., Weissenbach J., Westhof E., Wincker P., Jubin C.,
RA Poulain J., Barbe V., Segurens B., Artiguenave F., Anthouard V.,
RA Vacherie B., Val M.-E., Fulton R.S., Minx P., Wilson R., Durrens P.,
RA Jean G., Marck C., Martin T., Nikolski M., Rolland T., Seret M.-L.,
RA Casaregola S., Despons L., Fairhead C., Fischer G., Lafontaine I., Leh V.,
RA Lemaire M., de Montigny J., Neuveglise C., Thierry A., Blanc-Lenfle I.,
RA Bleykasten C., Diffels J., Fritsch E., Frangeul L., Goeffon A.,
RA Jauniaux N., Kachouri-Lafond R., Payen C., Potier S., Pribylova L.,
RA Ozanne C., Richard G.-F., Sacerdot C., Straub M.-L., Talla E.;
RT "Comparative genomics of protoploid Saccharomycetaceae.";
RL Genome Res. 19:1696-1709(2009).
CC -!- SIMILARITY: Belongs to the OSBP family.
CC {ECO:0000256|ARBA:ARBA00008842}.
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DR EMBL; CU928173; CAR25666.1; -; Genomic_DNA.
DR RefSeq; XP_002494599.1; XM_002494554.1.
DR STRING; 559307.C5DPQ5; -.
DR GeneID; 8201682; -.
DR KEGG; zro:ZYRO0A05258g; -.
DR HOGENOM; CLU_001040_1_1_1; -.
DR InParanoid; C5DPQ5; -.
DR Proteomes; UP000008536; Chromosome A.
DR GO; GO:0008289; F:lipid binding; IEA:UniProtKB-KW.
DR GO; GO:0006869; P:lipid transport; IEA:UniProtKB-KW.
DR CDD; cd13292; PH_Osh1p_Osh2p_yeast; 1.
DR Gene3D; 2.40.160.120; -; 1.
DR Gene3D; 3.30.70.3490; -; 1.
DR Gene3D; 1.25.40.20; Ankyrin repeat-containing domain; 2.
DR Gene3D; 2.30.29.30; Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB); 1.
DR InterPro; IPR002110; Ankyrin_rpt.
DR InterPro; IPR036770; Ankyrin_rpt-contain_sf.
DR InterPro; IPR037239; OSBP_sf.
DR InterPro; IPR000648; Oxysterol-bd.
DR InterPro; IPR011993; PH-like_dom_sf.
DR InterPro; IPR001849; PH_domain.
DR PANTHER; PTHR10972:SF205; OXYSTEROL-BINDING PROTEIN; 1.
DR PANTHER; PTHR10972; OXYSTEROL-BINDING PROTEIN-RELATED; 1.
DR Pfam; PF00023; Ank; 1.
DR Pfam; PF01237; Oxysterol_BP; 1.
DR Pfam; PF00169; PH; 1.
DR SMART; SM00248; ANK; 2.
DR SMART; SM00233; PH; 1.
DR SUPFAM; SSF48403; Ankyrin repeat; 1.
DR SUPFAM; SSF144000; Oxysterol-binding protein-like; 1.
DR SUPFAM; SSF50729; PH domain-like; 1.
DR PROSITE; PS50297; ANK_REP_REGION; 1.
DR PROSITE; PS50088; ANK_REPEAT; 2.
DR PROSITE; PS50003; PH_DOMAIN; 1.
PE 3: Inferred from homology;
KW ANK repeat {ECO:0000256|PROSITE-ProRule:PRU00023};
KW Lipid transport {ECO:0000256|ARBA:ARBA00023055};
KW Lipid-binding {ECO:0000256|ARBA:ARBA00023121};
KW Reference proteome {ECO:0000313|Proteomes:UP000008536};
KW Transport {ECO:0000256|ARBA:ARBA00022448}.
FT REPEAT 128..150
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 228..260
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT DOMAIN 312..410
FT /note="PH"
FT /evidence="ECO:0000259|PROSITE:PS50003"
FT REGION 1..42
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 469..674
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 793..813
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 826..1114
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 10..40
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 473..510
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 528..546
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 558..622
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 649..665
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 794..813
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 830..854
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 861..876
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 879..904
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 934..961
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1077..1091
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1092..1114
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1548 AA; 173332 MW; 49D7981EAC2FBB39 CRC64;
MDRDSVAIIS PGGQSYSSSS NLDPQLDRTR SQSTGNESGE HDVALASKPL LKLKLLDSLR
QGNFKQLEAL IKNEFQPVGD PNVEEVRNLV LHYAVQVAPA ALIKDIVREW ANNTRGGITI
DINYRDENGD TPLHLSAFQS RGDVIEFLMD QPHVNDCILN NSHLQPVEMC RNLSIAHMMQ
AKRATYVAEI AQEFRTAFNN RDFGHLDSIL VNPRNAELLD INGMDPETGD TVLHEFVKKR
DVIMCRWLLE HGADPFNRDR QGRLPVDLVG KVNENDSATN TKVAIDIELK KLLGKAAKEQ
SVIDVTNNLH EPPTHKGYLR KWTNFAQGYK LRWFILSGDG KLSYYKDQAD TRNACRGSLN
MSTCYLHLDS SEKLKFEIIG GSNGAIRWHL KANHPIETNR WVWAIQGAIR FAKDRELLMK
SGTVPPSLAM SRGLNAGGRY DSPLYSSQLQ YNQGGGKNSQ LLDEELGVSD GSAQQGRMPS
SSDHRNKRVS TASITSNDLR LNNNLTESGK EYVNRMVGNR LDSSSREGRS RTNSNLSHNH
ANERSGHNSL VGGVAGHPGN SQINNQKRQV NETQGEDRLP QQQSQQEEQQ YYGHHQTNAN
VQPKKSTPLE ASSTQLTSTA RTPEHAGGAF EPAPTDSIDS HVPSNEDELD NFSDEEEDNQ
DRNSNFDVDD EDVKTQYGPY SQRLSMLQRS LSMELSSLKE LLDTGHPSEE AWGMLRKSLG
SISNTFEKLY FLTSSRDKKL GSLLAKQREV NNVWIQSVKD LELELIEKSN RLASLDKERR
GLKKLLHKKL SEAGASTDGS QFDSTTSRQV DDSNATLEGI AKFIEATREE DEESDAEVFF
DAEDLVDASD EDEERYPSES TNQTKPDSSE GSIPQHGDRS YGNKKEEEGK SQNRDTDYNG
KDAEQKFSIN EPPSTAPPPV PSTHEDTTSQ KVPEEVRPES QYSSSDQTRI SSASHNRNPF
RETEGQYAAE GASKNNEDIG KETENFERNE GQAGGAPSSN ELKQLNTKVP DERSRKEPSS
TGSPVEMARD KVGTPQEPQV LRPQGKRPPK DVGSGAAVAG GVAAGAGGAA GVSKSDSTKN
QKEDFGPRHD SNQSSMKKPS ANKPEQQDGT AQDNELMNLP MVGETEKQKQ KYSVILKEGS
FKGYEDGVRK RLRIDDDDRP AISLWSVLKS MVGKDMTRMS LPVTFNEPTS LLQRVAEDLE
YSDLLDTAST FEDSSLRMLY VAVFTASSYA STVKRVAKPF NPLLGETYEY CRPDKGYRFF
TEQVCHHPVV SATWTESAKW DFWGESNVDT GFNGRSFNIK HLGLWYIKMR PDSSEGEELY
TWKKPNNTVI GILVGNPQVD NNGEVEVVNH TTGDRCLINF RARGWRSQGA YEVTGEVFDK
NNNKKWILGG HWNDAIYAKM ATPKNDSDIM KTKDTSSTGP KFDGSKFLVW KASPRPEAPF
NLTPFAITLN APQPSLVPWV APTDTRLRPD QREMEDGVYD KAGDEKHRLE QKQRMVRRKR
AETGEVHKPV WFHKEVHPVT KSEYWQFNGD YWKLRKDHKL KEVCPDIF
//
