ID C5DV67_ZYGRC Unreviewed; 442 AA.
AC C5DV67;
DT 28-JUL-2009, integrated into UniProtKB/TrEMBL.
DT 28-JUL-2009, sequence version 1.
DT 24-JAN-2024, entry version 66.
DE RecName: Full=Magnesium transporter {ECO:0000256|RuleBase:RU366042};
GN OrderedLocusNames=ZYRO0D04290g {ECO:0000313|EMBL:CAR27686.1};
OS Zygosaccharomyces rouxii (strain ATCC 2623 / CBS 732 / NBRC 1130 / NCYC 568
OS / NRRL Y-229) (Candida mogii).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC Saccharomycetales; Saccharomycetaceae; Zygosaccharomyces.
OX NCBI_TaxID=559307 {ECO:0000313|EMBL:CAR27686.1, ECO:0000313|Proteomes:UP000008536};
RN [1] {ECO:0000313|Proteomes:UP000008536}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 2623 / CBS 732 / BCRC 21506 / NBRC 1130 / NCYC 568 / NRRL
RC Y-229 {ECO:0000313|Proteomes:UP000008536};
RX PubMed=19525356; DOI=10.1101/gr.091546.109;
RG The Genolevures Consortium;
RA Souciet J.-L., Dujon B., Gaillardin C., Johnston M., Baret P.V.,
RA Cliften P., Sherman D.J., Weissenbach J., Westhof E., Wincker P., Jubin C.,
RA Poulain J., Barbe V., Segurens B., Artiguenave F., Anthouard V.,
RA Vacherie B., Val M.-E., Fulton R.S., Minx P., Wilson R., Durrens P.,
RA Jean G., Marck C., Martin T., Nikolski M., Rolland T., Seret M.-L.,
RA Casaregola S., Despons L., Fairhead C., Fischer G., Lafontaine I., Leh V.,
RA Lemaire M., de Montigny J., Neuveglise C., Thierry A., Blanc-Lenfle I.,
RA Bleykasten C., Diffels J., Fritsch E., Frangeul L., Goeffon A.,
RA Jauniaux N., Kachouri-Lafond R., Payen C., Potier S., Pribylova L.,
RA Ozanne C., Richard G.-F., Sacerdot C., Straub M.-L., Talla E.;
RT "Comparative genomics of protoploid Saccharomycetaceae.";
RL Genome Res. 19:1696-1709(2009).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}. Mitochondrion
CC inner membrane {ECO:0000256|RuleBase:RU366042}; Multi-pass membrane
CC protein {ECO:0000256|RuleBase:RU366042}.
CC -!- SIMILARITY: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35)
CC family. {ECO:0000256|ARBA:ARBA00009765, ECO:0000256|RuleBase:RU366042}.
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DR EMBL; CU928176; CAR27686.1; -; Genomic_DNA.
DR RefSeq; XP_002496619.1; XM_002496574.1.
DR AlphaFoldDB; C5DV67; -.
DR GeneID; 8203870; -.
DR KEGG; zro:ZYRO0D04290g; -.
DR HOGENOM; CLU_025144_1_0_1; -.
DR InParanoid; C5DV67; -.
DR Proteomes; UP000008536; Chromosome D.
DR GO; GO:0005743; C:mitochondrial inner membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0046873; F:metal ion transmembrane transporter activity; IEA:InterPro.
DR GO; GO:0015693; P:magnesium ion transport; IEA:UniProt.
DR CDD; cd12823; Mrs2_Mfm1p-like; 1.
DR Gene3D; 2.40.128.330; -; 1.
DR Gene3D; 1.20.58.340; Magnesium transport protein CorA, transmembrane region; 1.
DR InterPro; IPR045863; CorA_TM1_TM2.
DR InterPro; IPR002523; MgTranspt_CorA/ZnTranspt_ZntB.
DR InterPro; IPR039204; MRS2-like.
DR PANTHER; PTHR13890:SF27; MAGNESIUM TRANSPORTER MRS2, MITOCHONDRIAL; 1.
DR PANTHER; PTHR13890; RNA SPLICING PROTEIN MRS2, MITOCHONDRIAL; 1.
DR Pfam; PF01544; CorA; 1.
DR SUPFAM; SSF144083; Magnesium transport protein CorA, transmembrane region; 1.
PE 3: Inferred from homology;
KW Ion transport {ECO:0000256|RuleBase:RU366042};
KW Magnesium {ECO:0000256|RuleBase:RU366042};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|RuleBase:RU366042};
KW Mitochondrion {ECO:0000256|RuleBase:RU366042};
KW Mitochondrion inner membrane {ECO:0000256|RuleBase:RU366042};
KW Reference proteome {ECO:0000313|Proteomes:UP000008536};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692,
KW ECO:0000256|RuleBase:RU366042};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|RuleBase:RU366042}; Transport {ECO:0000256|RuleBase:RU366042}.
FT TRANSMEM 312..330
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU366042"
FT TRANSMEM 342..363
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU366042"
SQ SEQUENCE 442 AA; 51266 MW; FCEFA81BE1A62C61 CRC64;
MQQFFRNIPR FRFLGRLNPT RFVSTTDTSS RRLPLTTKNK QLLSLKPITP SDSYVSCTIF
NDRGDVTAVS QKFPKWTFLR DHSLYPRDLR KIDTTTVDII PSILVKPHCI VVNMLHIKAL
IERDKVYVFD TSNPSAAAKL GVLMYDLESK LSSRRGPTVN GTTPQAYEHS ALESMLINVM
SDLETEYKIH HALCGHILSE LENEVDRDKL RDLLIKSKNL SLFYQKSLLI REMLDELLEN
DEDLAGMYLE VKKTEEDDFA DLEMLLETYY TQCDEYVQQA ESLIQDIKST EEIVNIILDA
NRNALMLLEL KVTIYTLGFT VATLVPAFYG MNLKNFIEEN NWGFLSVVIF SVTSALVVTA
ANFRALRSIT RLTMLNNHSG ARSPRHKQMA TQYAEEHIPL LWQRCKRWTN DIWHGKARSN
RFKQGQEDRE IIWRWLLDDE RK
//
