ID C5DXE3_ZYGRC Unreviewed; 431 AA.
AC C5DXE3;
DT 28-JUL-2009, integrated into UniProtKB/TrEMBL.
DT 28-JUL-2009, sequence version 1.
DT 27-MAR-2024, entry version 76.
DE SubName: Full=ZYRO0F04334p {ECO:0000313|EMBL:CAR28454.1};
GN OrderedLocusNames=ZYRO0F04334g {ECO:0000313|EMBL:CAR28454.1};
OS Zygosaccharomyces rouxii (strain ATCC 2623 / CBS 732 / NBRC 1130 / NCYC 568
OS / NRRL Y-229) (Candida mogii).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC Saccharomycetales; Saccharomycetaceae; Zygosaccharomyces.
OX NCBI_TaxID=559307 {ECO:0000313|EMBL:CAR28454.1, ECO:0000313|Proteomes:UP000008536};
RN [1] {ECO:0000313|Proteomes:UP000008536}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 2623 / CBS 732 / BCRC 21506 / NBRC 1130 / NCYC 568 / NRRL
RC Y-229 {ECO:0000313|Proteomes:UP000008536};
RX PubMed=19525356; DOI=10.1101/gr.091546.109;
RG The Genolevures Consortium;
RA Souciet J.-L., Dujon B., Gaillardin C., Johnston M., Baret P.V.,
RA Cliften P., Sherman D.J., Weissenbach J., Westhof E., Wincker P., Jubin C.,
RA Poulain J., Barbe V., Segurens B., Artiguenave F., Anthouard V.,
RA Vacherie B., Val M.-E., Fulton R.S., Minx P., Wilson R., Durrens P.,
RA Jean G., Marck C., Martin T., Nikolski M., Rolland T., Seret M.-L.,
RA Casaregola S., Despons L., Fairhead C., Fischer G., Lafontaine I., Leh V.,
RA Lemaire M., de Montigny J., Neuveglise C., Thierry A., Blanc-Lenfle I.,
RA Bleykasten C., Diffels J., Fritsch E., Frangeul L., Goeffon A.,
RA Jauniaux N., Kachouri-Lafond R., Payen C., Potier S., Pribylova L.,
RA Ozanne C., Richard G.-F., Sacerdot C., Straub M.-L., Talla E.;
RT "Comparative genomics of protoploid Saccharomycetaceae.";
RL Genome Res. 19:1696-1709(2009).
CC -!- SIMILARITY: Belongs to the tRNA pseudouridine synthase TruA family.
CC {ECO:0000256|ARBA:ARBA00009375}.
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DR EMBL; CU928178; CAR28454.1; -; Genomic_DNA.
DR RefSeq; XP_002497387.1; XM_002497342.1.
DR AlphaFoldDB; C5DXE3; -.
DR STRING; 559307.C5DXE3; -.
DR GeneID; 8205145; -.
DR KEGG; zro:ZYRO0F04334g; -.
DR HOGENOM; CLU_014673_2_0_1; -.
DR InParanoid; C5DXE3; -.
DR Proteomes; UP000008536; Chromosome F.
DR GO; GO:0009982; F:pseudouridine synthase activity; IEA:InterPro.
DR GO; GO:0003723; F:RNA binding; IEA:InterPro.
DR GO; GO:0001522; P:pseudouridine synthesis; IEA:InterPro.
DR GO; GO:0008033; P:tRNA processing; IEA:UniProtKB-KW.
DR CDD; cd02569; PseudoU_synth_ScPus3; 1.
DR Gene3D; 3.30.70.660; Pseudouridine synthase I, catalytic domain, C-terminal subdomain; 1.
DR Gene3D; 3.30.70.580; Pseudouridine synthase I, catalytic domain, N-terminal subdomain; 1.
DR HAMAP; MF_00171; TruA; 1.
DR InterPro; IPR020103; PsdUridine_synth_cat_dom_sf.
DR InterPro; IPR001406; PsdUridine_synth_TruA.
DR InterPro; IPR020097; PsdUridine_synth_TruA_a/b_dom.
DR InterPro; IPR020095; PsdUridine_synth_TruA_C.
DR InterPro; IPR041707; Pus3-like.
DR InterPro; IPR020094; TruA/RsuA/RluB/E/F_N.
DR NCBIfam; TIGR00071; hisT_truA; 1.
DR PANTHER; PTHR11142; PSEUDOURIDYLATE SYNTHASE; 1.
DR PANTHER; PTHR11142:SF5; TRNA PSEUDOURIDINE(38_39) SYNTHASE; 1.
DR Pfam; PF01416; PseudoU_synth_1; 1.
DR SUPFAM; SSF55120; Pseudouridine synthase; 1.
PE 3: Inferred from homology;
KW Isomerase {ECO:0000256|ARBA:ARBA00023235};
KW Reference proteome {ECO:0000313|Proteomes:UP000008536};
KW tRNA processing {ECO:0000256|ARBA:ARBA00022694}.
FT DOMAIN 227..334
FT /note="Pseudouridine synthase I TruA alpha/beta"
FT /evidence="ECO:0000259|Pfam:PF01416"
SQ SEQUENCE 431 AA; 49551 MW; CEFFBB3CF39F0804 CRC64;
MGVLQRLFRL INKPGLRSGE MSLPTASNYS AWTKEQLIEK IVELENHQDV QNSKKHKKAS
PELPKTKRRR EFDFSKYNTR FIALKFSYLG WNYNGLAVQK DVTPLPTVEG VIIDALMKCR
LVASSNVQDF RFSRCGRTDK GVSAMNQVIS LEVRSNLSDE EQKDPSNDTR ELQYAQILNH
LLPEDIKISA MCLRPPEGFD ARYSCEYRHY KYLFSGKGLM LDRMQKAAAL YHGEHDFRNF
CKLDGSKQIT NYTRNILGSE IQHISDNMYC FDLVGSAFLW HQVRCMMAIL FLVGQGLEEP
SVITNLLDVD KTPQKPIYEM ASDLPLILYD CKFPEMEWIQ PTSADYKAIK YSKVIESLNL
HYQFKATVAN MFAECLALQP DSNADFSNKT RINVGDGVGK VVSKYEKMVN RQVMDSAETV
NEKYRNRKNT K
//
