ID C5EZ65_9HELI Unreviewed; 754 AA.
AC C5EZ65;
DT 28-JUL-2009, integrated into UniProtKB/TrEMBL.
DT 28-JUL-2009, sequence version 1.
DT 24-JAN-2024, entry version 55.
DE RecName: Full=Flagellar biosynthesis protein FlhA {ECO:0000256|RuleBase:RU364093};
GN Name=flhA {ECO:0000256|RuleBase:RU364093,
GN ECO:0000313|EMBL:EEQ63180.1};
GN ORFNames=HPMG_00637 {ECO:0000313|EMBL:EEQ63180.1};
OS Helicobacter pullorum MIT 98-5489.
OC Bacteria; Campylobacterota; Epsilonproteobacteria; Campylobacterales;
OC Helicobacteraceae; Helicobacter.
OX NCBI_TaxID=537972 {ECO:0000313|EMBL:EEQ63180.1};
RN [1] {ECO:0000313|EMBL:EEQ63180.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=MIT 98-5489 {ECO:0000313|EMBL:EEQ63180.1};
RG The Broad Institute Genome Sequencing Platform;
RA Fox J.G., Shen Z., Charoenlap N., Schauer D.B., Ward D., Mehta T.,
RA Young S., Jaffe D., Gnerre S., Berlin A., Heiman D., Hepburn T., Shea T.,
RA Sykes S., Alvarado L., Kodira C., Borodovsky M., Lander E., Galagan J.,
RA Nusbaum C., Birren B.;
RT "Annotation of Helicobacter pullorum strain MIT 98-5489.";
RL Submitted (AUG-2008) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Required for formation of the rod structure of the flagellar
CC apparatus. Together with FliI and FliH, may constitute the export
CC apparatus of flagellin. {ECO:0000256|RuleBase:RU364093}.
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|RuleBase:RU364093};
CC Multi-pass membrane protein {ECO:0000256|RuleBase:RU364093}. Membrane
CC {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the FHIPEP (flagella/HR/invasion proteins export
CC pore) family. {ECO:0000256|ARBA:ARBA00008835,
CC ECO:0000256|RuleBase:RU364093}.
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DR EMBL; DS990442; EEQ63180.1; -; Genomic_DNA.
DR RefSeq; WP_005021401.1; NZ_DS990442.1.
DR AlphaFoldDB; C5EZ65; -.
DR eggNOG; COG1298; Bacteria.
DR HOGENOM; CLU_015346_3_0_7; -.
DR Proteomes; UP000003953; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0044780; P:bacterial-type flagellum assembly; IEA:InterPro.
DR GO; GO:0009306; P:protein secretion; IEA:InterPro.
DR Gene3D; 3.40.30.60; FHIPEP family, domain 1; 1.
DR Gene3D; 1.10.8.540; FHIPEP family, domain 3; 1.
DR Gene3D; 3.40.50.12790; FHIPEP family, domain 4; 1.
DR InterPro; IPR042194; FHIPEP_1.
DR InterPro; IPR042193; FHIPEP_3.
DR InterPro; IPR042196; FHIPEP_4.
DR InterPro; IPR006301; FlhA.
DR InterPro; IPR001712; T3SS_FHIPEP.
DR NCBIfam; TIGR01398; FlhA; 1.
DR PANTHER; PTHR30161:SF1; FLAGELLAR BIOSYNTHESIS PROTEIN FLHA-RELATED; 1.
DR PANTHER; PTHR30161; FLAGELLAR EXPORT PROTEIN, MEMBRANE FLHA SUBUNIT-RELATED; 1.
DR Pfam; PF00771; FHIPEP; 1.
DR PRINTS; PR00949; TYPE3IMAPROT.
PE 3: Inferred from homology;
KW Bacterial flagellum biogenesis {ECO:0000256|RuleBase:RU364093};
KW Bacterial flagellum protein export {ECO:0000256|RuleBase:RU364093};
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475,
KW ECO:0000256|RuleBase:RU364093};
KW Cell projection {ECO:0000313|EMBL:EEQ63180.1};
KW Cilium {ECO:0000313|EMBL:EEQ63180.1};
KW Flagellum {ECO:0000313|EMBL:EEQ63180.1};
KW Membrane {ECO:0000256|ARBA:ARBA00023136};
KW Protein transport {ECO:0000256|RuleBase:RU364093};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989};
KW Transport {ECO:0000256|RuleBase:RU364093}.
FT REGION 356..401
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 363..389
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 754 AA; 82319 MW; 9BF26FCE853D5415 CRC64;
MAKAGQKTSF WGRISPFLSQ LTGSKDLTVV FFIIAILAII IVPLPSALLD FFLAISIALS
ALIILIALYV KKPTDFSAFP TLLLIVTLFR LSLNIATTRM ILSNGHLGPE AVSDIITAFG
QFVVGGNYVI GIILFIILVI INFMVVTNGS TRVSEVKARF TLDAMPGKQM AIDADLNTGL
IGQEEAKARR DELAAEADFY GSMDGANKFV KGDAIAGIII TLINIIGGFL IGVFQKDMSV
ADAASTFTIL TIGDGLVSQL PALIVSTATG IIVTRFSKEG ENFASGIVDQ LINESKTLMI
VGCILLLFAL VPGLPTISLG FVGLLFLTLA LLLNKQKDGE AWKYVESLFK KVRKGKAEEG
QAPLPQRQTQ RASGGQTPQN AQQAAPKPQP QESEEERRKR EEAEIDKALK VKILRVGLGY
QLIKFADPAQ GGELVNKIRA IRKTMATEYG ILVPMVHLRD DLNLAPDEYQ ILLKEIEIGK
GKIMVDKYLA IASSGFVGEL PDGIPTKEPV FGLDAYWIDE DKKEDAIIEG YTIIDGATVI
STHIQELIKQ YAEELLTRQE VANLVAKLGQ DYPILAEEIK GVGIGTIQHI LKELLHEQIP
IKDMLSIAEA IADGYPAYKA DLPTLSEYVR ACLKRLITHN FQSDDGVLKY FVLSPSLEQF
LLEKLPDQQK IGQRLRLSPT ESQSLLDAIN VAYQKGVSMG AVPTIIGGVP MVLRKPLAIF
LEQYGFGRNI VVLSTAEIDY QSKFEILGSI EFPI
//
