ID C5FR28_ARTOC Unreviewed; 600 AA.
AC C5FR28;
DT 28-JUL-2009, integrated into UniProtKB/TrEMBL.
DT 28-JUL-2009, sequence version 1.
DT 27-MAR-2024, entry version 69.
DE SubName: Full=Protein kinase {ECO:0000313|EMBL:EEQ32331.1};
GN ORFNames=MCYG_05150 {ECO:0000313|EMBL:EEQ32331.1};
OS Arthroderma otae (strain ATCC MYA-4605 / CBS 113480) (Microsporum canis).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Eurotiomycetidae; Onygenales; Arthrodermataceae; Microsporum.
OX NCBI_TaxID=554155 {ECO:0000313|EMBL:EEQ32331.1, ECO:0000313|Proteomes:UP000002035};
RN [1] {ECO:0000313|Proteomes:UP000002035}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC MYA-4605 / CBS 113480 {ECO:0000313|Proteomes:UP000002035};
RX PubMed=22951933; DOI=10.1128/mbio.00259-12;
RA Martinez D.A., Oliver B.G., Graeser Y., Goldberg J.M., Li W.,
RA Martinez-Rossi N.M., Monod M., Shelest E., Barton R.C., Birch E.,
RA Brakhage A.A., Chen Z., Gurr S.J., Heiman D., Heitman J., Kosti I.,
RA Rossi A., Saif S., Samalova M., Saunders C.W., Shea T., Summerbell R.C.,
RA Xu J., Young S., Zeng Q., Birren B.W., Cuomo C.A., White T.C.;
RT "Comparative genome analysis of Trichophyton rubrum and related
RT dermatophytes reveals candidate genes involved in infection.";
RL MBio 3:E259-E259(2012).
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DR EMBL; DS995705; EEQ32331.1; -; Genomic_DNA.
DR RefSeq; XP_002845281.1; XM_002845235.1.
DR AlphaFoldDB; C5FR28; -.
DR STRING; 554155.C5FR28; -.
DR GeneID; 9230236; -.
DR VEuPathDB; FungiDB:MCYG_05150; -.
DR eggNOG; KOG0598; Eukaryota.
DR HOGENOM; CLU_000288_120_0_1; -.
DR OMA; DQFQGFS; -.
DR OrthoDB; 10768at2759; -.
DR Proteomes; UP000002035; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR GO; GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
DR GO; GO:0016310; P:phosphorylation; IEA:UniProtKB-KW.
DR CDD; cd11651; YPK1_N_like; 1.
DR Gene3D; 1.10.510.10; Transferase(Phosphotransferase) domain 1; 1.
DR InterPro; IPR000961; AGC-kinase_C.
DR InterPro; IPR011009; Kinase-like_dom_sf.
DR InterPro; IPR017892; Pkinase_C.
DR InterPro; IPR000719; Prot_kinase_dom.
DR InterPro; IPR017441; Protein_kinase_ATP_BS.
DR InterPro; IPR008271; Ser/Thr_kinase_AS.
DR PANTHER; PTHR24351; RIBOSOMAL PROTEIN S6 KINASE; 1.
DR PANTHER; PTHR24351:SF243; RIBOSOMAL PROTEIN S6 KINASE; 1.
DR Pfam; PF00069; Pkinase; 1.
DR Pfam; PF00433; Pkinase_C; 1.
DR SMART; SM00133; S_TK_X; 1.
DR SMART; SM00220; S_TKc; 1.
DR SUPFAM; SSF56112; Protein kinase-like (PK-like); 1.
DR PROSITE; PS51285; AGC_KINASE_CTER; 1.
DR PROSITE; PS00107; PROTEIN_KINASE_ATP; 1.
DR PROSITE; PS50011; PROTEIN_KINASE_DOM; 1.
DR PROSITE; PS00108; PROTEIN_KINASE_ST; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000256|PROSITE-
KW ProRule:PRU10141};
KW Kinase {ECO:0000256|ARBA:ARBA00022777, ECO:0000313|EMBL:EEQ32331.1};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741, ECO:0000256|PROSITE-
KW ProRule:PRU10141}; Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW Reference proteome {ECO:0000313|Proteomes:UP000002035};
KW Serine/threonine-protein kinase {ECO:0000256|ARBA:ARBA00022527};
KW Transferase {ECO:0000256|ARBA:ARBA00022679}.
FT DOMAIN 254..511
FT /note="Protein kinase"
FT /evidence="ECO:0000259|PROSITE:PS50011"
FT DOMAIN 512..583
FT /note="AGC-kinase C-terminal"
FT /evidence="ECO:0000259|PROSITE:PS51285"
FT REGION 23..58
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 111..131
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 23..46
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 111..128
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT BINDING 287
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU10141"
SQ SEQUENCE 600 AA; 66964 MW; 89845715678070FB CRC64;
MSWNITKKLK ETHLSALSNF SSSLASSKDK DVLTPTTPTA SSASSAKEGG PAPDVNTSKP
GILVVTLYEG RGFSLPEQHR EAFASHHRTN SSTGGVAGST QQNSLAHTSV TRANGSTRPQ
TSGGGFTGIP TNHGRISRKY MPYALLDFDK LQVFINSIDG SPENPVWAGS STQYKFDVSR
IAQLTVHMYL RNPNAAPGAG RSQDIFLGVA QISPQFDGPY REVEWIDLQY GTGKIQIGWE
YVETQTNKLN VDDFELLKVV GKGSFGKVMQ VRKKDTHRIY AMKIIRKAKI ISRQEVTHTL
AERSVLAQIN NPFIVPLKFT FQSPEKLYFI LAFVNGGELF YHLTKEQRFD INRSRFYTAE
LLCALECLHG FNVIYRDLKP ENILLDYQGH IALCDFGLCK LEMKDEDETH TFCGTPEYLA
PELLTGNGYN KTVDWWTLGV LLYEMLTGLP PFYAEDTNEM YRKILSDPLN FPSHDIVPAT
AKDLLTKLLN RDPAERLGAN GSAEIKAHPF FHAIDWRKLL QRKYEPAFKP NVVDALDTAN
FDVQFTSEPA QDSFVDDPVL SQTMQNQFAG FSYNRPVAGL NDAGGSIKDP SFIDNVQDRS
//
