ID   C5FXU5_ARTOC            Unreviewed;      1097 AA.
AC   C5FXU5;
DT   28-JUL-2009, integrated into UniProtKB/TrEMBL.
DT   28-JUL-2009, sequence version 1.
DT   27-MAR-2024, entry version 60.
DE   SubName: Full=Tetratricopeptide repeat domain-containing protein {ECO:0000313|EMBL:EEQ34343.1};
GN   ORFNames=MCYG_07162 {ECO:0000313|EMBL:EEQ34343.1};
OS   Arthroderma otae (strain ATCC MYA-4605 / CBS 113480) (Microsporum canis).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC   Eurotiomycetidae; Onygenales; Arthrodermataceae; Microsporum.
OX   NCBI_TaxID=554155 {ECO:0000313|EMBL:EEQ34343.1, ECO:0000313|Proteomes:UP000002035};
RN   [1] {ECO:0000313|Proteomes:UP000002035}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC MYA-4605 / CBS 113480 {ECO:0000313|Proteomes:UP000002035};
RX   PubMed=22951933; DOI=10.1128/mbio.00259-12;
RA   Martinez D.A., Oliver B.G., Graeser Y., Goldberg J.M., Li W.,
RA   Martinez-Rossi N.M., Monod M., Shelest E., Barton R.C., Birch E.,
RA   Brakhage A.A., Chen Z., Gurr S.J., Heiman D., Heitman J., Kosti I.,
RA   Rossi A., Saif S., Samalova M., Saunders C.W., Shea T., Summerbell R.C.,
RA   Xu J., Young S., Zeng Q., Birren B.W., Cuomo C.A., White T.C.;
RT   "Comparative genome analysis of Trichophyton rubrum and related
RT   dermatophytes reveals candidate genes involved in infection.";
RL   MBio 3:E259-E259(2012).
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DR   EMBL; DS995707; EEQ34343.1; -; Genomic_DNA.
DR   RefSeq; XP_002843379.1; XM_002843333.1.
DR   AlphaFoldDB; C5FXU5; -.
DR   STRING; 554155.C5FXU5; -.
DR   GeneID; 9227966; -.
DR   VEuPathDB; FungiDB:MCYG_07162; -.
DR   eggNOG; ENOG502SICG; Eukaryota.
DR   HOGENOM; CLU_000288_125_7_1; -.
DR   OMA; GNIASIW; -.
DR   OrthoDB; 2695287at2759; -.
DR   Proteomes; UP000002035; Unassembled WGS sequence.
DR   GO; GO:0043531; F:ADP binding; IEA:InterPro.
DR   Gene3D; 3.40.50.1820; alpha/beta hydrolase; 1.
DR   Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR   Gene3D; 1.25.40.10; Tetratricopeptide repeat domain; 2.
DR   InterPro; IPR029058; AB_hydrolase.
DR   InterPro; IPR002182; NB-ARC.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR011990; TPR-like_helical_dom_sf.
DR   InterPro; IPR019734; TPR_repeat.
DR   PANTHER; PTHR35205; NB-ARC AND TPR DOMAIN PROTEIN; 1.
DR   PANTHER; PTHR35205:SF1; ORC1-LIKE AAA ATPASE DOMAIN-CONTAINING PROTEIN; 1.
DR   Pfam; PF00931; NB-ARC; 1.
DR   Pfam; PF13424; TPR_12; 1.
DR   PRINTS; PR00364; DISEASERSIST.
DR   SMART; SM00028; TPR; 4.
DR   SUPFAM; SSF53474; alpha/beta-Hydrolases; 1.
DR   SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR   SUPFAM; SSF48452; TPR-like; 2.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000002035}.
FT   DOMAIN          391..603
FT                   /note="NB-ARC"
FT                   /evidence="ECO:0000259|Pfam:PF00931"
SQ   SEQUENCE   1097 AA;  123596 MW;  19BF875865BB7DC5 CRC64;
     MPLQKLRLVQ TRDGNSAKGN VDIILVAGIN MPSVREWSIL SQQWTSFFES TDSCVNIFTF
     DYDITLDNNF TFQTLLDEGH RLLAALSQHQ QRNMRPFIFV CHSLGSFIVK QALCVANAQK
     HSYSAILNSV LAIMFLGALH LPSAPEKLSE QYNLILRSIS NDISKQGFAR IAKESWLLAN
     ISKLFGDIEM QVEILSLYET EETRIRVGMM DGKGLFSSHR SFMLSGPEVS NIGAIREQQF
     RLAGTHIELP RLQQPDGQPH HQIQEWLRFV LSNSYRQAAE RILSPDAPSP TISLTSLSSY
     DAARIALKGS NCQPTTANSA TNEATAGSSI TKEWQLVPIL DGFNTPRRLA KLPCFMIDIP
     VRNNTFFGRE SIIQDLDKLL LPPERPTTSS LANSDRRHVA LCGIGGIGKT SIAIEYVFSR
     KEKFDAIFWI RSDEASKLDH DFCRIAMELG LQDTSEAFNP VVCRELAKGW LENPVRVLDH
     EHDIVSQADA QWLIVFDNAD SPDLLQDYWP LSSNGSILVT SRDPLAKSSP SISSKYIDLA
     PLGNNEGAEL LQRLSHVTEN VEVSVKIAAK LGGLPLAISQ MAAIIRYQYL SFPEFYERYE
     DESDRRELHS LNIVTPRPEA RGNIASIWAV EQLGPHAACL LEVSAMLDPD CIQERLFTGD
     LGAVGQLEDF PKTSFAYSAA RADLIKRSLI TRNADKREFR IHRVLQDSVL SKLTPGKMLQ
     TFSFAVDLVL AAWGSTPLVQ RHAISLARSR DGLFSHTLAM RSLFEKHYQA KVHGPGLQVA
     KLMNEAGWYQ HEKGNSEDIK PFLKLALEIC NQTPGPESAQ LLTDIHYGLA AAANETNDRA
     ACLHHTEQLL KLRLKASLST GVKDIRLAIA HNEYGIALVM NHEYEKAIAE FNTSIEVYRG
     LEDYWPSMDT NPRTNLGFTY WVMGDLDQSW QTLRDLLDDR ETKFGVNDRE SYRTGRVYHG
     LGNICYDRGL FDESYNWHQR ALAHYQATLG SNHHKTADLC HRVAKHCLRR QEKEYTRILI
     DQALKVYSLR ESIYLPELAR TTFLKAQFAM NSGDVLEAIE LFKNAKDMRS QIPDAPCKPD
     ASLREDDFDQ LVTFFSR
//