ID C5H7L7_9CAUD Unreviewed; 181 AA.
AC C5H7L7;
DT 28-JUL-2009, integrated into UniProtKB/TrEMBL.
DT 28-JUL-2009, sequence version 1.
DT 27-MAR-2024, entry version 52.
DE RecName: Full=dihydrofolate reductase {ECO:0000256|ARBA:ARBA00012856};
DE EC=1.5.1.3 {ECO:0000256|ARBA:ARBA00012856};
GN Name=frd {ECO:0000313|EMBL:ACJ71901.1};
OS Escherichia phage wV8.
OC Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes;
OC Ounavirinae; Felixounavirus; Felixounavirus wV8.
OX NCBI_TaxID=576791 {ECO:0000313|EMBL:ACJ71901.1, ECO:0000313|Proteomes:UP000201889};
RN [1] {ECO:0000313|EMBL:ACJ71901.1, ECO:0000313|Proteomes:UP000201889}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=19379502;
RA Villegas A., She Y.M., Kropinski A.M., Lingohr E.J., Mazzocco A., Ojha S.,
RA Waddell T.E., Ackermann H.W., Moyles D.M., Ahmed R., Johnson R.P.;
RT "The genome and proteome of a virulent Escherichia coli O157:H7
RT bacteriophage closely resembling Salmonella phage Felix O1.";
RL Virol. J. 6:41-41(2009).
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DR EMBL; EU877232; ACJ71901.1; -; Genomic_DNA.
DR RefSeq; YP_002922870.1; NC_012749.1.
DR GeneID; 7944088; -.
DR KEGG; vg:7944088; -.
DR OrthoDB; 9577at10239; -.
DR Proteomes; UP000201889; Genome.
DR GO; GO:0004146; F:dihydrofolate reductase activity; IEA:UniProtKB-EC.
DR GO; GO:0050661; F:NADP binding; IEA:InterPro.
DR GO; GO:0006545; P:glycine biosynthetic process; IEA:InterPro.
DR GO; GO:0006730; P:one-carbon metabolic process; IEA:UniProtKB-KW.
DR GO; GO:0046654; P:tetrahydrofolate biosynthetic process; IEA:InterPro.
DR CDD; cd00209; DHFR; 1.
DR Gene3D; 3.40.430.10; Dihydrofolate Reductase, subunit A; 1.
DR InterPro; IPR012259; DHFR.
DR InterPro; IPR024072; DHFR-like_dom_sf.
DR InterPro; IPR001796; DHFR_dom.
DR PANTHER; PTHR48069; DIHYDROFOLATE REDUCTASE; 1.
DR PANTHER; PTHR48069:SF3; DIHYDROFOLATE REDUCTASE; 1.
DR Pfam; PF00186; DHFR_1; 1.
DR PRINTS; PR00070; DHFR.
DR SUPFAM; SSF53597; Dihydrofolate reductase-like; 1.
DR PROSITE; PS51330; DHFR_2; 1.
PE 4: Predicted;
FT DOMAIN 1..181
FT /note="DHFR"
FT /evidence="ECO:0000259|PROSITE:PS51330"
SQ SEQUENCE 181 AA; 20371 MW; 5713B023119EA3B7 CRC64;
MIKLIFASGE HGEFGTPTGM PWPRHKQDMQ EFKRLTKNNL VVMGNETFKT LGSKPLPERT
NLVLTNSVPY LGIDFDKDDV MYAKASKESF GAFLKYLDSS IDEDVFVIGG AGVLVDALPY
AGVVFHTVFH KVTEEATVYL PFENFFDKLY DSRVFAKVQS RPSDDGKATF EIYVPQVKGH
F
//
