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Database: UniProt
Entry: C5J5F8_MYCCR
LinkDB: C5J5F8_MYCCR
Original site: C5J5F8_MYCCR 
ID   C5J5F8_MYCCR            Unreviewed;       470 AA.
AC   C5J5F8;
DT   28-JUL-2009, integrated into UniProtKB/TrEMBL.
DT   28-JUL-2009, sequence version 1.
DT   05-JUL-2017, entry version 59.
DE   RecName: Full=Chromosomal replication initiator protein DnaA {ECO:0000256|RuleBase:RU000577};
GN   Name=dnaA {ECO:0000313|EMBL:CAT04680.1};
GN   OrderedLocusNames=MCJ_000010 {ECO:0000313|EMBL:CAT04680.1};
OS   Mycoplasma conjunctivae (strain ATCC 25834 / HRC/581 / NCTC 10147).
OC   Bacteria; Tenericutes; Mollicutes; Mycoplasmataceae; Mycoplasma.
OX   NCBI_TaxID=572263 {ECO:0000313|Proteomes:UP000001491};
RN   [1] {ECO:0000313|Proteomes:UP000001491}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 25834 / HRC/581 / NCTC 10147
RC   {ECO:0000313|Proteomes:UP000001491};
RX   PubMed=19534756; DOI=10.1186/1471-2105-10-S6-S7;
RA   Calderon-Copete S.P., Wigger G., Wunderlin C., Schmidheini T.,
RA   Frey J., Quail M.A., Falquet L.;
RT   "The Mycoplasma conjunctivae genome sequencing, annotation and
RT   analysis.";
RL   BMC Bioinformatics 10:S7-S7(2009).
CC   -!- FUNCTION: Plays an important role in the initiation and regulation
CC       of chromosomal replication. Binds to the origin of replication; it
CC       binds specifically double-stranded DNA at a 9 bp consensus (dnaA
CC       box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic
CC       phospholipids. {ECO:0000256|RuleBase:RU000577,
CC       ECO:0000256|SAAS:SAAS00731907}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|SAAS:SAAS00756131}.
CC   -!- SIMILARITY: Belongs to the DnaA family.
CC       {ECO:0000256|RuleBase:RU004227, ECO:0000256|SAAS:SAAS00555179}.
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DR   EMBL; FM864216; CAT04680.1; -; Genomic_DNA.
DR   STRING; 572263.MCJ_000010; -.
DR   EnsemblBacteria; CAT04680; CAT04680; MCJ_000010.
DR   KEGG; mco:MCJ_000010; -.
DR   eggNOG; ENOG4105CI4; Bacteria.
DR   eggNOG; COG0593; LUCA.
DR   HOGENOM; HOG000140554; -.
DR   KO; K02313; -.
DR   OMA; VENWVKD; -.
DR   OrthoDB; POG091H02FF; -.
DR   Proteomes; UP000001491; Chromosome.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0003688; F:DNA replication origin binding; IEA:InterPro.
DR   GO; GO:0006270; P:DNA replication initiation; IEA:InterPro.
DR   GO; GO:0006275; P:regulation of DNA replication; IEA:InterPro.
DR   CDD; cd06571; Bac_DnaA_C; 1.
DR   Gene3D; 1.10.1750.10; -; 1.
DR   InterPro; IPR003593; AAA+_ATPase.
DR   InterPro; IPR001957; Chromosome_initiator_DnaA.
DR   InterPro; IPR020591; Chromosome_initiator_DnaA-like.
DR   InterPro; IPR013317; DnaA.
DR   InterPro; IPR013159; DnaA_C.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR010921; Trp_repressor/repl_initiator.
DR   PANTHER; PTHR30050:SF12; PTHR30050:SF12; 1.
DR   Pfam; PF00308; Bac_DnaA; 1.
DR   Pfam; PF08299; Bac_DnaA_C; 1.
DR   PRINTS; PR00051; DNAA.
DR   SMART; SM00382; AAA; 1.
DR   SMART; SM00760; Bac_DnaA_C; 1.
DR   SUPFAM; SSF48295; SSF48295; 1.
DR   SUPFAM; SSF52540; SSF52540; 1.
DR   TIGRFAMs; TIGR00362; DnaA; 1.
PE   3: Inferred from homology;
KW   ATP-binding {ECO:0000256|RuleBase:RU000577,
KW   ECO:0000256|SAAS:SAAS00731922};
KW   Complete proteome {ECO:0000313|Proteomes:UP000001491};
KW   Cytoplasm {ECO:0000256|SAAS:SAAS00756112};
KW   DNA replication {ECO:0000256|RuleBase:RU004227,
KW   ECO:0000256|SAAS:SAAS00731887};
KW   DNA-binding {ECO:0000256|RuleBase:RU000577,
KW   ECO:0000256|SAAS:SAAS00756124};
KW   Nucleotide-binding {ECO:0000256|RuleBase:RU000577,
KW   ECO:0000256|SAAS:SAAS00731897};
KW   Reference proteome {ECO:0000313|Proteomes:UP000001491}.
FT   DOMAIN      152    288       AAA. {ECO:0000259|SMART:SM00382}.
FT   DOMAIN      374    443       Bac_DnaA_C. {ECO:0000259|SMART:SM00760}.
SQ   SEQUENCE   470 AA;  55081 MW;  516486186C94932A CRC64;
     MNKTDLEIKT INLKQSLEEF INDNMIFNNF FKNIKIISEN ESQIIIDVDN VKVKKELNSK
     WKGLLERAFI NIGIRKIITF NGLSETNNSS NDKQEEVVEK QDEEINFKVE ILNLELKHNN
     IIAKYTIENF VQGNYNKMVF GVYHNIIEKN KFFSPLFIYG ASGVGKTHFL SALGNSFIKK
     DKKVFYINDY KFTSIVTSWL RDKNEYSKIN QFIEWLSTID VLIIDDIQGF GNKTRTLSIL
     FQIINKFIEE DKQIVIASDT PPNILGGFED RLITRFKSGL VIEMNKPTKE DFVKIFKFKI
     EEEGLDKYYW SPEAIDFLSR HFHNSIRDME GALKKIIFYI QTDESFYENP DFSFSLEKIL
     EIFEEQKKFS QKTTYEVIIK ETCDFLGVDS KLVFGKSRVR EIVKARNISI WIIKNLLDYT
     HVNIGKIFGD RDHSTIVSIL KNVDREKAQN EAFNYEITEI QKKINTLSKQ
//
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