ID C5KCI5_PERM5 Unreviewed; 486 AA.
AC C5KCI5;
DT 28-JUL-2009, integrated into UniProtKB/TrEMBL.
DT 28-JUL-2009, sequence version 1.
DT 27-MAR-2024, entry version 57.
DE SubName: Full=Centromere/microtubule-binding protein CBF5, putative {ECO:0000313|EMBL:EER17847.1};
GN ORFNames=Pmar_PMAR023777 {ECO:0000313|EMBL:EER17847.1};
OS Perkinsus marinus (strain ATCC 50983 / TXsc).
OC Eukaryota; Sar; Alveolata; Perkinsozoa; Perkinsea; Perkinsida; Perkinsidae;
OC Perkinsus.
OX NCBI_TaxID=423536 {ECO:0000313|Proteomes:UP000007800};
RN [1] {ECO:0000313|EMBL:EER17847.1, ECO:0000313|Proteomes:UP000007800}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 50983 / TXsc {ECO:0000313|Proteomes:UP000007800};
RA El-Sayed N., Caler E., Inman J., Amedeo P., Hass B., Wortman J.;
RL Submitted (JUL-2008) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the pseudouridine synthase TruB family.
CC {ECO:0000256|ARBA:ARBA00008999}.
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DR EMBL; GG671995; EER17847.1; -; Genomic_DNA.
DR RefSeq; XP_002786051.1; XM_002786005.1.
DR AlphaFoldDB; C5KCI5; -.
DR EnsemblProtists; EER17847; EER17847; Pmar_PMAR023777.
DR GeneID; 9087038; -.
DR InParanoid; C5KCI5; -.
DR OrthoDB; 5472308at2759; -.
DR Proteomes; UP000007800; Unassembled WGS sequence.
DR GO; GO:0009982; F:pseudouridine synthase activity; IEA:InterPro.
DR GO; GO:0003723; F:RNA binding; IEA:InterPro.
DR GO; GO:0001522; P:pseudouridine synthesis; IEA:InterPro.
DR GO; GO:0006396; P:RNA processing; IEA:InterPro.
DR CDD; cd02572; PseudoU_synth_hDyskerin; 1.
DR CDD; cd21148; PUA_Cbf5; 1.
DR Gene3D; 3.30.2350.10; Pseudouridine synthase; 1.
DR Gene3D; 2.30.130.10; PUA domain; 1.
DR InterPro; IPR012960; Dyskerin-like.
DR InterPro; IPR020103; PsdUridine_synth_cat_dom_sf.
DR InterPro; IPR002501; PsdUridine_synth_N.
DR InterPro; IPR002478; PUA.
DR InterPro; IPR015947; PUA-like_sf.
DR InterPro; IPR036974; PUA_sf.
DR InterPro; IPR004802; tRNA_PsdUridine_synth_B_fam.
DR InterPro; IPR032819; TruB_C.
DR NCBIfam; TIGR00425; CBF5; 1.
DR PANTHER; PTHR23127; CENTROMERE/MICROTUBULE BINDING PROTEIN CBF5; 1.
DR PANTHER; PTHR23127:SF0; H_ACA RIBONUCLEOPROTEIN COMPLEX SUBUNIT DKC1; 1.
DR Pfam; PF08068; DKCLD; 1.
DR Pfam; PF01472; PUA; 1.
DR Pfam; PF16198; TruB_C_2; 1.
DR Pfam; PF01509; TruB_N; 1.
DR SMART; SM01136; DKCLD; 1.
DR SMART; SM00359; PUA; 1.
DR SUPFAM; SSF55120; Pseudouridine synthase; 1.
DR SUPFAM; SSF88697; PUA domain-like; 1.
DR PROSITE; PS50890; PUA; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000007800}.
FT DOMAIN 40..98
FT /note="Dyskerin-like"
FT /evidence="ECO:0000259|SMART:SM01136"
FT DOMAIN 289..363
FT /note="PUA"
FT /evidence="ECO:0000259|SMART:SM00359"
FT REGION 385..486
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 385..402
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 417..441
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 486 AA; 54283 MW; 16CCB290498B79A0 CRC64;
MAKTKKEAPT AAAAAASSTA DAQKSTDCMI KPSSVSPPIN TSEWPLLLKN YDRLNVRTGH
YTPLPFGCSP LNRPLDQHLL YGVCNLDKPV NPSSHEVVAW IKRILKCEKT GHSGTLDPKV
SGCLLVCLNR ATRLVKAQQG AGKEYVCVVR FHADPGGEAA IIRALDQLTG ALFQRPPVIA
AVKRQLRIRT IYWSKLLDYD EEKHMAVFHV SCEAGTYIRT LCVHMGLLLG VGAHMQELRR
VRSGNLGEQD QLVTMHDLLD AQYVYESTRS EEYLRRTIMP LERILVSYPR IVLKDSAVNA
VCYGAKLMVV GVLRFENGIE VGKDVVLMTT KGEAVALGIA QMTTAVIASV DHGCVATIKR
VIMERDTYDS RWGYGPRASE KKKLILNGKL DEKGRPNENT PESWLKHEGM IPKLTGTPAE
DKKESPKEES PEEEQETAPV KKEKKKHHKK RTVEEVEEAE EEEADEEVVE KKKKKKKSKH
HHEDEA
//
