ID C5KPD0_PERM5 Unreviewed; 565 AA.
AC C5KPD0;
DT 28-JUL-2009, integrated into UniProtKB/TrEMBL.
DT 28-JUL-2009, sequence version 1.
DT 24-JAN-2024, entry version 58.
DE SubName: Full=Eukaryotic translation initiation factor 5B, putative {ECO:0000313|EMBL:EER13663.1};
DE Flags: Fragment;
GN ORFNames=Pmar_PMAR005646 {ECO:0000313|EMBL:EER13663.1};
OS Perkinsus marinus (strain ATCC 50983 / TXsc).
OC Eukaryota; Sar; Alveolata; Perkinsozoa; Perkinsea; Perkinsida; Perkinsidae;
OC Perkinsus.
OX NCBI_TaxID=423536 {ECO:0000313|Proteomes:UP000007800};
RN [1] {ECO:0000313|EMBL:EER13663.1, ECO:0000313|Proteomes:UP000007800}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 50983 / TXsc {ECO:0000313|Proteomes:UP000007800};
RA El-Sayed N., Caler E., Inman J., Amedeo P., Hass B., Wortman J.;
RL Submitted (JUL-2008) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the TRAFAC class translation factor GTPase
CC superfamily. Classic translation factor GTPase family. IF-2 subfamily.
CC {ECO:0000256|ARBA:ARBA00007733}.
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DR EMBL; GG675027; EER13663.1; -; Genomic_DNA.
DR RefSeq; XP_002781868.1; XM_002781822.1.
DR AlphaFoldDB; C5KPD0; -.
DR EnsemblProtists; EER13663; EER13663; Pmar_PMAR005646.
DR GeneID; 9042878; -.
DR InParanoid; C5KPD0; -.
DR OMA; CHEVESD; -.
DR OrthoDB; 169393at2759; -.
DR Proteomes; UP000007800; Unassembled WGS sequence.
DR GO; GO:0005525; F:GTP binding; IEA:InterPro.
DR GO; GO:0003924; F:GTPase activity; IEA:InterPro.
DR GO; GO:0003743; F:translation initiation factor activity; IEA:UniProtKB-KW.
DR CDD; cd01887; IF2_eIF5B; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR Gene3D; 2.40.30.10; Translation factors; 1.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR005225; Small_GTP-bd_dom.
DR InterPro; IPR000795; T_Tr_GTP-bd_dom.
DR InterPro; IPR015760; TIF_IF2.
DR NCBIfam; TIGR00231; small_GTP; 1.
DR PANTHER; PTHR43381:SF4; EUKARYOTIC TRANSLATION INITIATION FACTOR 5B; 1.
DR PANTHER; PTHR43381; TRANSLATION INITIATION FACTOR IF-2-RELATED; 1.
DR Pfam; PF00009; GTP_EFTU; 1.
DR PRINTS; PR00315; ELONGATNFCT.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS51722; G_TR_2; 1.
PE 3: Inferred from homology;
KW Initiation factor {ECO:0000256|ARBA:ARBA00022540,
KW ECO:0000313|EMBL:EER13663.1};
KW Protein biosynthesis {ECO:0000256|ARBA:ARBA00022540,
KW ECO:0000313|EMBL:EER13663.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000007800}.
FT DOMAIN 269..484
FT /note="Tr-type G"
FT /evidence="ECO:0000259|PROSITE:PS51722"
FT REGION 1..227
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..22
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 55..128
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 174..192
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 199..213
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT NON_TER 565
FT /evidence="ECO:0000313|EMBL:EER13663.1"
SQ SEQUENCE 565 AA; 63508 MW; 59D2C2C6BD49A7B0 CRC64;
MSDQEKLSNQ EESHVDAKTI ANRKKREKKK AKAAAAATEG GKKMSAAAKL AAARLEAARE
AEEERKRLEE EAQKKAEEEE RLAAEEARKA QEEKERKAAE KKARRERLRA EGKLLSKKEK
EQKAKADAYR QMLLESGQLP AAVTASDEDS TTDKPKKQSD LYGKKKSHKH KKQPSRGELV
EERVVSTTHD DDDDDWEKAE EVVDKKSESE AESVDDWELL DEDSDDDKKV EAYPTHVKNK
PQKKEEVDVK GKFAAADPLA VFDSSTSEFR SPICCIMGHV DTGKTKLLDK IRRTTVQEGE
AGGITQQIGA TFFPEASLQD AVHKVNLTTY LQLPGLLIID TPGHESFNNL RVRGSSLCDI
AILVVDIMHG LEPQTIESLE LLRNRKCPFI IALNKIDRLY QWRSSANRPS RDSLKAQKDY
VKHEFDDRLK RIQLQLAERG LNTAVYWENH DVRRDVSIVP TSAVTGEGVP DLLYLIVKLT
QTLMAKKITR QPDLFQCTVL EVKNIEGLGT TIDVILVNGR IKETDQICVC TLAGPVVTTI
RALLTPPPAK EIRVKSEYVH HKVIN
//
