ID   C5KSX9_PERM5            Unreviewed;      1019 AA.
AC   C5KSX9;
DT   28-JUL-2009, integrated into UniProtKB/TrEMBL.
DT   28-JUL-2009, sequence version 1.
DT   27-MAR-2024, entry version 58.
DE   SubName: Full=ATP-dependent RNA helicase A, putative {ECO:0000313|EMBL:EER12329.1};
GN   ORFNames=Pmar_PMAR001127 {ECO:0000313|EMBL:EER12329.1};
OS   Perkinsus marinus (strain ATCC 50983 / TXsc).
OC   Eukaryota; Sar; Alveolata; Perkinsozoa; Perkinsea; Perkinsida; Perkinsidae;
OC   Perkinsus.
OX   NCBI_TaxID=423536 {ECO:0000313|Proteomes:UP000007800};
RN   [1] {ECO:0000313|EMBL:EER12329.1, ECO:0000313|Proteomes:UP000007800}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 50983 / TXsc {ECO:0000313|Proteomes:UP000007800};
RA   El-Sayed N., Caler E., Inman J., Amedeo P., Hass B., Wortman J.;
RL   Submitted (JUL-2008) to the EMBL/GenBank/DDBJ databases.
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DR   EMBL; GG676168; EER12329.1; -; Genomic_DNA.
DR   RefSeq; XP_002780534.1; XM_002780488.1.
DR   AlphaFoldDB; C5KSX9; -.
DR   EnsemblProtists; EER12329; EER12329; Pmar_PMAR001127.
DR   GeneID; 9057376; -.
DR   InParanoid; C5KSX9; -.
DR   OrthoDB; 1095660at2759; -.
DR   Proteomes; UP000007800; Unassembled WGS sequence.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0003725; F:double-stranded RNA binding; IEA:InterPro.
DR   GO; GO:0004386; F:helicase activity; IEA:UniProtKB-KW.
DR   GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR   CDD; cd19855; DSRM_DHX9_rpt2; 1.
DR   CDD; cd18791; SF2_C_RHA; 1.
DR   Gene3D; 1.20.120.1080; -; 1.
DR   Gene3D; 3.30.160.20; -; 2.
DR   Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR   InterPro; IPR011545; DEAD/DEAH_box_helicase_dom.
DR   InterPro; IPR044446; DHX9_DSRM_2.
DR   InterPro; IPR002464; DNA/RNA_helicase_DEAH_CS.
DR   InterPro; IPR014720; dsRBD_dom.
DR   InterPro; IPR007502; Helicase-assoc_dom.
DR   InterPro; IPR014001; Helicase_ATP-bd.
DR   InterPro; IPR001650; Helicase_C.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   PANTHER; PTHR18934; ATP-DEPENDENT RNA HELICASE; 1.
DR   PANTHER; PTHR18934:SF119; ATP-DEPENDENT RNA HELICASE A; 1.
DR   Pfam; PF00270; DEAD; 1.
DR   Pfam; PF00271; Helicase_C; 1.
DR   SMART; SM00487; DEXDc; 1.
DR   SMART; SM00358; DSRM; 1.
DR   SMART; SM00847; HA2; 1.
DR   SMART; SM00490; HELICc; 1.
DR   SUPFAM; SSF54768; dsRNA-binding domain-like; 2.
DR   SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR   PROSITE; PS00690; DEAH_ATP_HELICASE; 1.
DR   PROSITE; PS51192; HELICASE_ATP_BIND_1; 1.
DR   PROSITE; PS51194; HELICASE_CTER; 1.
PE   4: Predicted;
KW   ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW   Helicase {ECO:0000256|ARBA:ARBA00022806, ECO:0000313|EMBL:EER12329.1};
KW   Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW   Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW   Reference proteome {ECO:0000313|Proteomes:UP000007800}.
FT   DOMAIN          373..541
FT                   /note="Helicase ATP-binding"
FT                   /evidence="ECO:0000259|PROSITE:PS51192"
FT   DOMAIN          622..793
FT                   /note="Helicase C-terminal"
FT                   /evidence="ECO:0000259|PROSITE:PS51194"
SQ   SEQUENCE   1019 AA;  113714 MW;  465A9BC62F36B8EF CRC64;
     MSSVATSPPK VAVEHYVQGR PRKELYEYCQ KKGFKLDLHC DRRAPTAPWI CIASIGAIGK
     TAEGTGANKA KAADEACLKV LRLLGDSQLL EVASGSKRKG KKSEGVDTAA MEWYECSDQS
     TPPTTSSPGG TVGSGIGVVF RDGPAGYNSD NAKAAVFEWL KRRKMPTGFT YRPVNPKQPS
     TAGWTAQYNQ TVPGEELRLQ FSETASNKKT ASQYLALDIC SFLYEKGLIS ANTGKSVTMS
     NGVTNQMQRT SANAMPKPAD LPKPIVDDIL TSLGKWNIEL PSPPPPTERY VQLLPCLRVE
     PSPITSGPDI ESIQWQEPNG TYDPWKQVDI IPTESEATVS SRAREERAER QRYLVSHPFR
     EELPVDQFRD KLLSMIDQEQ VVLVSGATGS GKTTQVPQFI LDHYIMNDRA TSCNVVVTQP
     RRIAAISVAA RVAAERGEVV GANTVGYSVR FDTKNPQRPY GSIQYCTTGT LLRRLRRGLK
     GISHIVVDEI HERDLQTDFL LAILKSHVIG RTGIRIVLMS ATADVEHFVW YYGLSEGRQT
     LHVRRQQHQV TTYYLEDICQ LIDYDPHFRR SQANSSSIGD SMFRVNCNMN SRQVLGRGYS
     PRVIEGVESI DERELPTHLI VSILQWTAHT HGVEGGAVVV FLPGWPSIQG LLWVLRQEPE
     ITAIFDLLPL HSQIPPEDQQ KVFQKPPPGR RKCILSTNIA ETSLTIEDAV YIIDTCKCKL
     KYFHSERQMS SLDVSWAGKS NCKQRRGRCG RVRDGFCFRL ITKARYEHLQ EHIMPEMMRC
     EMMEPILAIL RLRLGDPRYV LHNCIDPPPP QAVEDALKKL MTMRAVEGNT GKLSDIGVFL
     ADLPADPPVG LSLIYSLILG VFDKAVTIAA MLCQGDPSAL SVQDKDTPPN AQLEPENMMF
     GYAVSDISDH AHLVEVFEQW DRLYSNYGHQ RASDFAWRSG YNNRSLVAVR NTRRQLLDFV
     YQKGPALIAT KTEAPAVKQW QLLTACLAAA LSPKFALHDT GKQAWVQYTE RAKIDRASR
//