ID C5LA47_PERM5 Unreviewed; 711 AA.
AC C5LA47;
DT 28-JUL-2009, integrated into UniProtKB/TrEMBL.
DT 28-JUL-2009, sequence version 1.
DT 27-MAR-2024, entry version 69.
DE SubName: Full=Glutathione s-transferase, putative {ECO:0000313|EMBL:EER06303.1};
GN ORFNames=Pmar_PMAR006069 {ECO:0000313|EMBL:EER06303.1};
OS Perkinsus marinus (strain ATCC 50983 / TXsc).
OC Eukaryota; Sar; Alveolata; Perkinsozoa; Perkinsea; Perkinsida; Perkinsidae;
OC Perkinsus.
OX NCBI_TaxID=423536 {ECO:0000313|Proteomes:UP000007800};
RN [1] {ECO:0000313|EMBL:EER06303.1, ECO:0000313|Proteomes:UP000007800}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 50983 / TXsc {ECO:0000313|Proteomes:UP000007800};
RA El-Sayed N., Caler E., Inman J., Amedeo P., Hass B., Wortman J.;
RL Submitted (JUL-2008) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; GG680729; EER06303.1; -; Genomic_DNA.
DR RefSeq; XP_002774487.1; XM_002774441.1.
DR AlphaFoldDB; C5LA47; -.
DR EnsemblProtists; EER06303; EER06303; Pmar_PMAR006069.
DR GeneID; 9065265; -.
DR InParanoid; C5LA47; -.
DR OrthoDB; 180563at2759; -.
DR Proteomes; UP000007800; Unassembled WGS sequence.
DR GO; GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0015385; F:sodium:proton antiporter activity; IEA:InterPro.
DR GO; GO:0016740; F:transferase activity; IEA:UniProtKB-KW.
DR GO; GO:0006885; P:regulation of pH; IEA:InterPro.
DR Gene3D; 6.10.140.1330; -; 1.
DR Gene3D; 3.40.30.10; Glutaredoxin; 1.
DR InterPro; IPR006153; Cation/H_exchanger.
DR InterPro; IPR018422; Cation/H_exchanger_CPA1.
DR InterPro; IPR004045; Glutathione_S-Trfase_N.
DR InterPro; IPR004709; NaH_exchanger.
DR InterPro; IPR036249; Thioredoxin-like_sf.
DR PANTHER; PTHR10110; SODIUM/HYDROGEN EXCHANGER; 1.
DR PANTHER; PTHR10110:SF191; SODIUM_HYDROGEN EXCHANGER; 1.
DR Pfam; PF02798; GST_N; 1.
DR Pfam; PF00999; Na_H_Exchanger; 1.
DR PRINTS; PR01084; NAHEXCHNGR.
DR SUPFAM; SSF52833; Thioredoxin-like; 1.
DR PROSITE; PS50404; GST_NTER; 1.
PE 4: Predicted;
KW Ion transport {ECO:0000256|ARBA:ARBA00023065};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000007800};
KW Sodium {ECO:0000256|ARBA:ARBA00023053};
KW Sodium transport {ECO:0000256|ARBA:ARBA00023201};
KW Transferase {ECO:0000313|EMBL:EER06303.1};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448}.
FT TRANSMEM 145..168
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 174..200
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 207..232
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 238..263
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 408..426
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 438..457
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 504..528
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 608..628
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 663..685
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 691..709
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 2..81
FT /note="GST N-terminal"
FT /evidence="ECO:0000259|PROSITE:PS50404"
SQ SEQUENCE 711 AA; 76307 MW; 16109F501047DD19 CRC64;
MSMYKLYYFY GRGRGEMVRF ALGLAGVDYE EQFIRTRQDM LNLMPKLRYG QVPMLETPDG
KRLVQTGAIL RYIARKFDLY GGAEGKEERV DEIIEASADA LGSGLLDVAI RFKFGQSFEE
AASTKGVKCL RWIKAWETQL EDGKFMAVVV VVVVVVVVAV VVFVFVVVVV VVVVVVVVVV
VVVVVVVVVV VVVVVVVVGV VGVVGVVGVV GVVGVVVVVV GVVVVVVGVV GVVGVVGVVG
VVGVVVVGVV GVVVVVVVVV VVVDFIALHS GTNTPTIADS CALRVVEEAI EVLGEEKVLG
AAPKVAAWRK ALLAVPRVAK FMKESPSATT WFPSAVEEGN TTTAVVTPKW RTIVVPVVVN
VTVPAAIETT VRVTTTTPTM VVPGNATTVE VPVVVPTASA IPEGKRDVYL ANGFFFLAVL
LGLSLLGGQF LKWARVRWLG ESGLATALGL LCGLLLYSVR AETMLEKVLE LNEEVFFFVL
LPPIIFQGGF CIDTKTLFKN FGTIVWLAVW ATLCSFMFIA GAVFLAGQLE LCSPWTIHEA
MGFATVISAT DPVAVLSILK SLSTAGPLLS GLIAGESLLN DAICLVLYRS LIHWEDRSLV
HALQTFVYVF FCSCLLGTAF AFASSLVYKY FPRENGGYEL TTRVVSSGEV DRGRYERGPE
VDAAGYGYSV VLEVSVLVLF VWMSYLLAEG LQLSGICAIL FCGIFMRKYT W
//
