ID   C5LIJ1_PERM5            Unreviewed;       894 AA.
AC   C5LIJ1;
DT   28-JUL-2009, integrated into UniProtKB/TrEMBL.
DT   28-JUL-2009, sequence version 1.
DT   27-MAR-2024, entry version 61.
DE   SubName: Full=ATP-dependent Clp protease, putative {ECO:0000313|EMBL:EER03394.1};
GN   ORFNames=Pmar_PMAR014611 {ECO:0000313|EMBL:EER03394.1};
OS   Perkinsus marinus (strain ATCC 50983 / TXsc).
OC   Eukaryota; Sar; Alveolata; Perkinsozoa; Perkinsea; Perkinsida; Perkinsidae;
OC   Perkinsus.
OX   NCBI_TaxID=423536 {ECO:0000313|Proteomes:UP000007800};
RN   [1] {ECO:0000313|EMBL:EER03394.1, ECO:0000313|Proteomes:UP000007800}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 50983 / TXsc {ECO:0000313|Proteomes:UP000007800};
RA   El-Sayed N., Caler E., Inman J., Amedeo P., Hass B., Wortman J.;
RL   Submitted (JUL-2008) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the ClpA/ClpB family.
CC       {ECO:0000256|RuleBase:RU004432}.
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DR   EMBL; GG682243; EER03394.1; -; Genomic_DNA.
DR   RefSeq; XP_002771578.1; XM_002771532.1.
DR   AlphaFoldDB; C5LIJ1; -.
DR   EnsemblProtists; EER03394; EER03394; Pmar_PMAR014611.
DR   GeneID; 9047481; -.
DR   OrthoDB; 275944at2759; -.
DR   Proteomes; UP000007800; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR   GO; GO:0008233; F:peptidase activity; IEA:UniProtKB-KW.
DR   GO; GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
DR   CDD; cd00009; AAA; 1.
DR   CDD; cd19499; RecA-like_ClpB_Hsp104-like; 1.
DR   Gene3D; 1.10.8.60; -; 2.
DR   Gene3D; 1.10.1780.10; Clp, N-terminal domain; 1.
DR   Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR   InterPro; IPR003593; AAA+_ATPase.
DR   InterPro; IPR003959; ATPase_AAA_core.
DR   InterPro; IPR019489; Clp_ATPase_C.
DR   InterPro; IPR036628; Clp_N_dom_sf.
DR   InterPro; IPR001270; ClpA/B.
DR   InterPro; IPR018368; ClpA/B_CS1.
DR   InterPro; IPR028299; ClpA/B_CS2.
DR   InterPro; IPR041546; ClpA/ClpB_AAA_lid.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   PANTHER; PTHR11638; ATP-DEPENDENT CLP PROTEASE; 1.
DR   PANTHER; PTHR11638:SF185; ATP-DEPENDENT CLP PROTEASE ATP-BINDING SUBUNIT; 1.
DR   Pfam; PF00004; AAA; 1.
DR   Pfam; PF07724; AAA_2; 1.
DR   Pfam; PF17871; AAA_lid_9; 1.
DR   Pfam; PF10431; ClpB_D2-small; 1.
DR   PRINTS; PR00300; CLPPROTEASEA.
DR   SMART; SM00382; AAA; 2.
DR   SMART; SM01086; ClpB_D2-small; 1.
DR   SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 2.
DR   PROSITE; PS00870; CLPAB_1; 1.
DR   PROSITE; PS00871; CLPAB_2; 1.
PE   3: Inferred from homology;
KW   ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000256|RuleBase:RU004432};
KW   Chaperone {ECO:0000256|RuleBase:RU004432};
KW   Hydrolase {ECO:0000313|EMBL:EER03394.1};
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741,
KW   ECO:0000256|RuleBase:RU004432}; Protease {ECO:0000313|EMBL:EER03394.1};
KW   Reference proteome {ECO:0000313|Proteomes:UP000007800};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        78..99
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          341..486
FT                   /note="AAA+ ATPase"
FT                   /evidence="ECO:0000259|SMART:SM00382"
FT   DOMAIN          627..782
FT                   /note="AAA+ ATPase"
FT                   /evidence="ECO:0000259|SMART:SM00382"
FT   DOMAIN          781..873
FT                   /note="Clp ATPase C-terminal"
FT                   /evidence="ECO:0000259|SMART:SM01086"
SQ   SEQUENCE   894 AA;  96966 MW;  42FAED636A6427C4 CRC64;
     MRQRGAADRR SRRSISTLLL CGVCLATAYV CGSTLFITPA LRQGARPASL RGGSVVGNLA
     VGSLSGGSRP RAWERSTLPY VFGAAAAVAV TLLSLALSMS RHRPKSASTE GGRSVARGSL
     ASWWNNMMFD PNRGDAARRQ VGRTAFDALS DSSARAIHRA QEESMNLATV PLEGLLIGLA
     SERSGGASKL LREAGVQVAE LKHLAPLQAA PDLVSWGAVE RVPLDDEVVE VIRGCVDKAQ
     GPITTEALLE GVIGKMLARP AGMEPELMGR LQSVLQRLQE WGEEDAEKIP VGGFVPGTSG
     GSVLESCGRN LTALAREGKL LKCVGRDAEI GRMIQVLSRM TKNNPVLLGE PGVGKTAVAE
     GMAELIARGE VPTHLAGVAI WDVSIGSLLA GTKYRGEFEE RLKRLVKEAT DADGKIILLI
     DELHTIVGAG ATGDGAIDAA NILKPALSRG ELRVIGATTQ SEYDKYIAKD PALERRFQPV
     VVPEPTQAQA VDMLMGVASL YEEHHFVRFT DDAIEACVKL SSRYIPSRRL PDSAFDAMDE
     AAARKRIQQG ARPSSRIEVN ANDVAQTVAQ WTGIPLEELT KDESARLLHM EERLDSRVIG
     QKRATSAVAR AIRRARVGVR GIGNKRPTAC FLFCGPTGVG KTELSKALSD EYFGEEGRNM
     IRLDMSEFME RHSVSKLIGS PPGYVGYDSN SGGVLTDRVR RQPHSLVLID EVEKAHPDVL
     NILLQVMDDG RLTDSHGRLA DFSNVILVMT SNVGSSMEDL KRHFRPEFIN RIDEVIAFDS
     LTEEDIVRIV GLYVSRLQAA LKEQHSIDLK VTDGLTAALG KEGYSAEFGA RHLNRVMQAR
     IEDPIAELIL REEIHRGEEL IADYDSERDM IVFRDANGRV LTETKCSDKT ATDD
//