ID C5LIT4_PERM5 Unreviewed; 520 AA.
AC C5LIT4;
DT 28-JUL-2009, integrated into UniProtKB/TrEMBL.
DT 28-JUL-2009, sequence version 1.
DT 27-MAR-2024, entry version 48.
DE RecName: Full=glycerol kinase {ECO:0000256|ARBA:ARBA00012099};
DE EC=2.7.1.30 {ECO:0000256|ARBA:ARBA00012099};
DE AltName: Full=ATP:glycerol 3-phosphotransferase {ECO:0000256|ARBA:ARBA00043149};
GN ORFNames=Pmar_PMAR014706 {ECO:0000313|EMBL:EER03487.1};
OS Perkinsus marinus (strain ATCC 50983 / TXsc).
OC Eukaryota; Sar; Alveolata; Perkinsozoa; Perkinsea; Perkinsida; Perkinsidae;
OC Perkinsus.
OX NCBI_TaxID=423536 {ECO:0000313|Proteomes:UP000007800};
RN [1] {ECO:0000313|EMBL:EER03487.1, ECO:0000313|Proteomes:UP000007800}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 50983 / TXsc {ECO:0000313|Proteomes:UP000007800};
RA El-Sayed N., Caler E., Inman J., Amedeo P., Hass B., Wortman J.;
RL Submitted (JUL-2008) to the EMBL/GenBank/DDBJ databases.
CC -!- PATHWAY: Polyol metabolism; glycerol degradation via glycerol kinase
CC pathway; sn-glycerol 3-phosphate from glycerol: step 1/1.
CC {ECO:0000256|ARBA:ARBA00005190}.
CC -!- SIMILARITY: Belongs to the FGGY kinase family.
CC {ECO:0000256|ARBA:ARBA00009156, ECO:0000256|RuleBase:RU003733}.
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DR EMBL; GG682243; EER03487.1; -; Genomic_DNA.
DR RefSeq; XP_002771671.1; XM_002771625.1.
DR AlphaFoldDB; C5LIT4; -.
DR EnsemblProtists; EER03487; EER03487; Pmar_PMAR014706.
DR GeneID; 9047725; -.
DR InParanoid; C5LIT4; -.
DR OMA; FMLMNIG; -.
DR OrthoDB; 2734344at2759; -.
DR UniPathway; UPA00618; UER00672.
DR Proteomes; UP000007800; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0004370; F:glycerol kinase activity; IEA:UniProtKB-EC.
DR GO; GO:0019563; P:glycerol catabolic process; IEA:UniProtKB-UniPathway.
DR GO; GO:0006072; P:glycerol-3-phosphate metabolic process; IEA:InterPro.
DR GO; GO:0016310; P:phosphorylation; IEA:UniProtKB-KW.
DR CDD; cd07769; FGGY_GK; 1.
DR Gene3D; 3.30.420.40; -; 2.
DR InterPro; IPR043129; ATPase_NBD.
DR InterPro; IPR000577; Carb_kinase_FGGY.
DR InterPro; IPR018483; Carb_kinase_FGGY_CS.
DR InterPro; IPR018485; FGGY_C.
DR InterPro; IPR018484; FGGY_N.
DR InterPro; IPR005999; Glycerol_kin.
DR NCBIfam; TIGR01311; glycerol_kin; 1.
DR PANTHER; PTHR10196:SF69; GLYCEROL KINASE; 1.
DR PANTHER; PTHR10196; SUGAR KINASE; 1.
DR Pfam; PF02782; FGGY_C; 1.
DR Pfam; PF00370; FGGY_N; 1.
DR PIRSF; PIRSF000538; GlpK; 1.
DR SUPFAM; SSF53067; Actin-like ATPase domain; 2.
DR PROSITE; PS00933; FGGY_KINASES_1; 1.
DR PROSITE; PS00445; FGGY_KINASES_2; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Glycerol metabolism {ECO:0000256|ARBA:ARBA00022798};
KW Kinase {ECO:0000256|RuleBase:RU003733, ECO:0000313|EMBL:EER03487.1};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000007800};
KW Transferase {ECO:0000256|RuleBase:RU003733}.
FT DOMAIN 13..271
FT /note="Carbohydrate kinase FGGY N-terminal"
FT /evidence="ECO:0000259|Pfam:PF00370"
FT DOMAIN 280..470
FT /note="Carbohydrate kinase FGGY C-terminal"
FT /evidence="ECO:0000259|Pfam:PF02782"
SQ SEQUENCE 520 AA; 56713 MW; 07A501648546022F CRC64;
MANLGGSNEH AKYVLAIDQG TTSSRAIIFG DDAQVLHVKG YPFEQKYPNP GWCEQDPYAI
LESTIKSVNE VAELIVPYGS ITAVGITNQR ETVIAWDKVT GKPLYNAIVW LDLRTYDTVK
ALTMDGSKDR FRHITGLPIS TYFTALKIRW LLDNVDEVSD AVKEGRCLFG TVDSWLTYNL
TGGHNNGGIH VTDVTNASRY MLMDLSKLEW CEDICNELGI PIDTLPNIVP SCGHIGTIAE
SPSHHGLELH PSLLNVPITA ILGDQQSALL GHGCVEDGQA KCTYGTGCFM LANTGDKIIQ
SSFGLLTTVA FQREGSPVKY ALEGSIAIAG RAVQWLRDQL GVIESAPEVE ELASTVPNTA
GVTVVPAFSG LFTPHWRPDA RAVIAGMTLG TTKAHICRAV LEGVALQVVD VVRVMERELE
HPLSEFYADG GMTSNNLLMQ MQADFLPKDI YPAMMAETTA FGAAYAAGLA LDLWKVPLQE
LIVNLGGHRK VEPHPAALER KRAIMRRWND ALQRSLGLEE
//
