ID C5MD60_CANTT Unreviewed; 508 AA.
AC C5MD60;
DT 28-JUL-2009, integrated into UniProtKB/TrEMBL.
DT 28-JUL-2009, sequence version 1.
DT 24-JAN-2024, entry version 50.
DE RecName: Full=UBX domain-containing protein {ECO:0000259|PROSITE:PS50033};
GN ORFNames=CTRG_04161 {ECO:0000313|EMBL:EER32490.1};
OS Candida tropicalis (strain ATCC MYA-3404 / T1) (Yeast).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC Saccharomycetales; Debaryomycetaceae; Candida/Lodderomyces clade; Candida.
OX NCBI_TaxID=294747 {ECO:0000313|EMBL:EER32490.1, ECO:0000313|Proteomes:UP000002037};
RN [1] {ECO:0000313|EMBL:EER32490.1, ECO:0000313|Proteomes:UP000002037}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC MYA-3404 / T1 {ECO:0000313|Proteomes:UP000002037};
RX PubMed=19465905; DOI=10.1038/nature08064;
RA Butler G., Rasmussen M.D., Lin M.F., Santos M.A., Sakthikumar S.,
RA Munro C.A., Rheinbay E., Grabherr M., Forche A., Reedy J.L., Agrafioti I.,
RA Arnaud M.B., Bates S., Brown A.J., Brunke S., Costanzo M.C.,
RA Fitzpatrick D.A., de Groot P.W., Harris D., Hoyer L.L., Hube B., Klis F.M.,
RA Kodira C., Lennard N., Logue M.E., Martin R., Neiman A.M., Nikolaou E.,
RA Quail M.A., Quinn J., Santos M.C., Schmitzberger F.F., Sherlock G.,
RA Shah P., Silverstein K.A., Skrzypek M.S., Soll D., Staggs R.,
RA Stansfield I., Stumpf M.P., Sudbery P.E., Srikantha T., Zeng Q., Berman J.,
RA Berriman M., Heitman J., Gow N.A., Lorenz M.C., Birren B.W., Kellis M.,
RA Cuomo C.A.;
RT "Evolution of pathogenicity and sexual reproduction in eight Candida
RT genomes.";
RL Nature 459:657-662(2009).
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DR EMBL; GG692399; EER32490.1; -; Genomic_DNA.
DR RefSeq; XP_002549864.1; XM_002549818.1.
DR AlphaFoldDB; C5MD60; -.
DR STRING; 294747.C5MD60; -.
DR EnsemblFungi; CTRG_04161-t43_1; CTRG_04161-t43_1-p1; CTRG_04161.
DR GeneID; 8299425; -.
DR KEGG; ctp:CTRG_04161; -.
DR VEuPathDB; FungiDB:CTRG_04161; -.
DR eggNOG; KOG1364; Eukaryota.
DR HOGENOM; CLU_021255_2_1_1; -.
DR OrthoDB; 5482878at2759; -.
DR Proteomes; UP000002037; Unassembled WGS sequence.
DR GO; GO:0043161; P:proteasome-mediated ubiquitin-dependent protein catabolic process; IEA:EnsemblFungi.
DR CDD; cd02958; UAS; 1.
DR CDD; cd14346; UBA_Ubx5_like; 1.
DR CDD; cd01767; UBX; 1.
DR Gene3D; 1.10.8.10; DNA helicase RuvA subunit, C-terminal domain; 1.
DR Gene3D; 3.40.30.10; Glutaredoxin; 1.
DR InterPro; IPR036249; Thioredoxin-like_sf.
DR InterPro; IPR006577; UAS.
DR InterPro; IPR029071; Ubiquitin-like_domsf.
DR InterPro; IPR001012; UBX_dom.
DR PANTHER; PTHR23322; FAS-ASSOCIATED PROTEIN; 1.
DR PANTHER; PTHR23322:SF6; UBX DOMAIN-CONTAINING PROTEIN 7; 1.
DR Pfam; PF13899; Thioredoxin_7; 1.
DR Pfam; PF14555; UBA_4; 1.
DR Pfam; PF00789; UBX; 1.
DR SMART; SM00594; UAS; 1.
DR SMART; SM00166; UBX; 1.
DR SUPFAM; SSF52833; Thioredoxin-like; 1.
DR SUPFAM; SSF54236; Ubiquitin-like; 1.
DR PROSITE; PS50033; UBX; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000002037}.
FT DOMAIN 419..506
FT /note="UBX"
FT /evidence="ECO:0000259|PROSITE:PS50033"
FT REGION 42..69
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 137..193
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 389..408
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 43..64
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 143..169
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 170..189
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 508 AA; 58212 MW; 1BEFAFF53518B82F CRC64;
MDEHIPTFLA VTGVEDESIA KQFLDVAGGD LETAVMLYME SGQHGGASSS NNNQSNTNSG
NASGYDDDEE MAKRLQEEAY RDNDDVREAD ANVHRHETLV DLGGGMPMHS MNRPMDFLGN
RRQGIFNQGM DFDSRMNAGF GDSIYDDDDD DDEDDDEDDD EIQVLDSDED EDGVNVRPIS
RRRQHIRNRN QELSSTQRRL ANLFRPPFDI IQNMNLDDAK RVGRESKKWI LINIQDSSEF
QCQVMNRDFF SNERIKQIIK DNFIFLQYQV DSMSGQQYVN FYHADEYPHL AILDPLTGER
VHKWKDGQVP IVNEWINQVY NFLDTFSLNP QSNNPLVHHE AKIDPSTLSE EQQIELAMKQ
SIIDNGTTNN INKSGTTIDD AIVIDGSDDE EPEIVSSPSE EISKDPFDSI LPINHPEPTE
QPMTRIQIRF PNGKRLVRKL KLDDKVIIIY EWLKFVLQDN YQDYGLQSPD ERFNLSNSSD
KSLKFIESLD KTIEEANLKN ASILLEQE
//
