ID C5MIC7_CANTT Unreviewed; 802 AA.
AC C5MIC7;
DT 28-JUL-2009, integrated into UniProtKB/TrEMBL.
DT 28-JUL-2009, sequence version 1.
DT 27-MAR-2024, entry version 79.
DE SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:EER30421.1};
GN ORFNames=CTRG_05820 {ECO:0000313|EMBL:EER30421.1};
OS Candida tropicalis (strain ATCC MYA-3404 / T1) (Yeast).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC Saccharomycetales; Debaryomycetaceae; Candida/Lodderomyces clade; Candida.
OX NCBI_TaxID=294747 {ECO:0000313|EMBL:EER30421.1, ECO:0000313|Proteomes:UP000002037};
RN [1] {ECO:0000313|EMBL:EER30421.1, ECO:0000313|Proteomes:UP000002037}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC MYA-3404 / T1 {ECO:0000313|Proteomes:UP000002037};
RX PubMed=19465905; DOI=10.1038/nature08064;
RA Butler G., Rasmussen M.D., Lin M.F., Santos M.A., Sakthikumar S.,
RA Munro C.A., Rheinbay E., Grabherr M., Forche A., Reedy J.L., Agrafioti I.,
RA Arnaud M.B., Bates S., Brown A.J., Brunke S., Costanzo M.C.,
RA Fitzpatrick D.A., de Groot P.W., Harris D., Hoyer L.L., Hube B., Klis F.M.,
RA Kodira C., Lennard N., Logue M.E., Martin R., Neiman A.M., Nikolaou E.,
RA Quail M.A., Quinn J., Santos M.C., Schmitzberger F.F., Sherlock G.,
RA Shah P., Silverstein K.A., Skrzypek M.S., Soll D., Staggs R.,
RA Stansfield I., Stumpf M.P., Sudbery P.E., Srikantha T., Zeng Q., Berman J.,
RA Berriman M., Heitman J., Gow N.A., Lorenz M.C., Birren B.W., Kellis M.,
RA Cuomo C.A.;
RT "Evolution of pathogenicity and sexual reproduction in eight Candida
RT genomes.";
RL Nature 459:657-662(2009).
CC -!- SIMILARITY: Belongs to the protein-tyrosine phosphatase family. Non-
CC receptor class subfamily. {ECO:0000256|ARBA:ARBA00009649}.
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DR EMBL; GG692404; EER30421.1; -; Genomic_DNA.
DR RefSeq; XP_002546342.1; XM_002546296.1.
DR AlphaFoldDB; C5MIC7; -.
DR STRING; 294747.C5MIC7; -.
DR EnsemblFungi; CTRG_05820-t43_1; CTRG_05820-t43_1-p1; CTRG_05820.
DR GeneID; 8300169; -.
DR KEGG; ctp:CTRG_05820; -.
DR VEuPathDB; FungiDB:CTRG_05820; -.
DR eggNOG; KOG0789; Eukaryota.
DR HOGENOM; CLU_007989_0_0_1; -.
DR OrthoDB; 1342035at2759; -.
DR Proteomes; UP000002037; Unassembled WGS sequence.
DR GO; GO:0004725; F:protein tyrosine phosphatase activity; IEA:InterPro.
DR GO; GO:0016311; P:dephosphorylation; IEA:InterPro.
DR CDD; cd18533; PTP_fungal; 1.
DR Gene3D; 3.90.190.10; Protein tyrosine phosphatase superfamily; 1.
DR Gene3D; 3.40.250.10; Rhodanese-like domain; 1.
DR InterPro; IPR029021; Prot-tyrosine_phosphatase-like.
DR InterPro; IPR000242; PTP_cat.
DR InterPro; IPR001763; Rhodanese-like_dom.
DR InterPro; IPR036873; Rhodanese-like_dom_sf.
DR InterPro; IPR016130; Tyr_Pase_AS.
DR InterPro; IPR003595; Tyr_Pase_cat.
DR InterPro; IPR000387; Tyr_Pase_dom.
DR PANTHER; PTHR19134; RECEPTOR-TYPE TYROSINE-PROTEIN PHOSPHATASE; 1.
DR PANTHER; PTHR19134:SF551; TYROSINE-PROTEIN PHOSPHATASE 3; 1.
DR Pfam; PF00581; Rhodanese; 1.
DR Pfam; PF00102; Y_phosphatase; 1.
DR PRINTS; PR00700; PRTYPHPHTASE.
DR SMART; SM00194; PTPc; 1.
DR SMART; SM00404; PTPc_motif; 1.
DR SUPFAM; SSF52799; (Phosphotyrosine protein) phosphatases II; 1.
DR SUPFAM; SSF52821; Rhodanese/Cell cycle control phosphatase; 1.
DR PROSITE; PS50206; RHODANESE_3; 1.
DR PROSITE; PS00383; TYR_PHOSPHATASE_1; 1.
DR PROSITE; PS50056; TYR_PHOSPHATASE_2; 1.
DR PROSITE; PS50055; TYR_PHOSPHATASE_PTP; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000002037}.
FT DOMAIN 262..330
FT /note="Rhodanese"
FT /evidence="ECO:0000259|PROSITE:PS50206"
FT DOMAIN 549..795
FT /note="Tyrosine-protein phosphatase"
FT /evidence="ECO:0000259|PROSITE:PS50055"
FT DOMAIN 703..786
FT /note="Tyrosine specific protein phosphatases"
FT /evidence="ECO:0000259|PROSITE:PS50056"
FT REGION 1..74
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 104..125
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..59
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 802 AA; 90954 MW; B0F945576454C04B CRC64;
MSKETMAFTF PNSNTSTQFK IPQPPITPTT NTTNNTNNFT SPLSQQQQQQ TPSTNTTPIR
KRQPKHKSFN NSISSITSST SDLTIYESSI LSSKQLSTDT LIDEKQLPPL PPPPTSSASK
HRYNQSLDSN RTLVSLDENE EDKFKFTINN NIDCNNNSNT SSSPIDSFFQ LSTPPPPIKD
PQPDFFNQQH SRPKLPTMHS TPSLKKQVTL PSLSFDLSLK NIKQEQSKRL NYIPSQNFRP
DIEKLSDRIQ YVCPIEFQGL CTAQDNLVID IRPFVEYSKS HVKSSLNICL PSTLLKRSNF
SLIRSINSLP DFEKNRFTEF LNNTKGDLVV YDSTENSSNL YHICNKIITC ANFMTCPEKK
ICLLDTNFSR FNELFPNAME TASPEVEDNN FLSPIIVPEK LRSSSVSDLS PYHKATPLSS
SSSSSMLSAN TPILSANFTL PSKCKSFKIR HNEELPTIPC GNPFEENTAN LFKLSNIPSD
CSKLPEWIKQ TIFDESGNPV TFKINNQFYS LEKLEQKRLI TALSLNTVND ISPMNEVAPK
ISCGIEFGNK NRYKDIFLYD HSRVELGHVN NNPNDISNYI NASFIEPPEK YHHPESKYIA
TQGPLDETMG DLWKLVLIRN IPLVISLTDS IENGIMKCAP FWQSGIYKSY EDTIRVTVVN
NEEIDENLIV RTFKIKCNDE PSREVKQIQL LSWPDMGTTS DPRDILKVVG LKQKILAESS
IKDKTTLVHC SAGCGRTGTL CVIDTLINYL KDNGDLNTEE EDPVFEITNH FRKLRISMVQ
TLKQYYLIYE TLISYFDNKN QQ
//
