ID C5MIG0_CANTT Unreviewed; 214 AA.
AC C5MIG0;
DT 28-JUL-2009, integrated into UniProtKB/TrEMBL.
DT 28-JUL-2009, sequence version 1.
DT 27-MAR-2024, entry version 60.
DE RecName: Full=Dethiobiotin synthetase {ECO:0008006|Google:ProtNLM};
GN ORFNames=CTRG_05853 {ECO:0000313|EMBL:EER30454.1};
OS Candida tropicalis (strain ATCC MYA-3404 / T1) (Yeast).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC Saccharomycetales; Debaryomycetaceae; Candida/Lodderomyces clade; Candida.
OX NCBI_TaxID=294747 {ECO:0000313|EMBL:EER30454.1, ECO:0000313|Proteomes:UP000002037};
RN [1] {ECO:0000313|EMBL:EER30454.1, ECO:0000313|Proteomes:UP000002037}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC MYA-3404 / T1 {ECO:0000313|Proteomes:UP000002037};
RX PubMed=19465905; DOI=10.1038/nature08064;
RA Butler G., Rasmussen M.D., Lin M.F., Santos M.A., Sakthikumar S.,
RA Munro C.A., Rheinbay E., Grabherr M., Forche A., Reedy J.L., Agrafioti I.,
RA Arnaud M.B., Bates S., Brown A.J., Brunke S., Costanzo M.C.,
RA Fitzpatrick D.A., de Groot P.W., Harris D., Hoyer L.L., Hube B., Klis F.M.,
RA Kodira C., Lennard N., Logue M.E., Martin R., Neiman A.M., Nikolaou E.,
RA Quail M.A., Quinn J., Santos M.C., Schmitzberger F.F., Sherlock G.,
RA Shah P., Silverstein K.A., Skrzypek M.S., Soll D., Staggs R.,
RA Stansfield I., Stumpf M.P., Sudbery P.E., Srikantha T., Zeng Q., Berman J.,
RA Berriman M., Heitman J., Gow N.A., Lorenz M.C., Birren B.W., Kellis M.,
RA Cuomo C.A.;
RT "Evolution of pathogenicity and sexual reproduction in eight Candida
RT genomes.";
RL Nature 459:657-662(2009).
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DR EMBL; GG692404; EER30454.1; -; Genomic_DNA.
DR RefSeq; XP_002546375.1; XM_002546329.1.
DR AlphaFoldDB; C5MIG0; -.
DR STRING; 294747.C5MIG0; -.
DR EnsemblFungi; CTRG_05853-t43_1; CTRG_05853-t43_1-p1; CTRG_05853.
DR GeneID; 8300202; -.
DR KEGG; ctp:CTRG_05853; -.
DR VEuPathDB; FungiDB:CTRG_05853; -.
DR eggNOG; ENOG502RXZU; Eukaryota.
DR HOGENOM; CLU_072551_2_0_1; -.
DR OrthoDB; 2022241at2759; -.
DR UniPathway; UPA00078; -.
DR Proteomes; UP000002037; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR GO; GO:0004141; F:dethiobiotin synthase activity; IEA:EnsemblFungi.
DR GO; GO:0000287; F:magnesium ion binding; IEA:InterPro.
DR GO; GO:0009102; P:biotin biosynthetic process; IEA:UniProtKB-UniPathway.
DR CDD; cd03109; DTBS; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR HAMAP; MF_00336; BioD; 1.
DR InterPro; IPR004472; DTB_synth_BioD.
DR InterPro; IPR027417; P-loop_NTPase.
DR NCBIfam; TIGR00347; bioD; 1.
DR PANTHER; PTHR43210; DETHIOBIOTIN SYNTHETASE; 1.
DR PANTHER; PTHR43210:SF5; DETHIOBIOTIN SYNTHETASE; 1.
DR Pfam; PF13500; AAA_26; 1.
DR PIRSF; PIRSF006755; DTB_synth; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
PE 3: Inferred from homology;
KW Biotin biosynthesis {ECO:0000256|ARBA:ARBA00022756};
KW Reference proteome {ECO:0000313|Proteomes:UP000002037}.
SQ SEQUENCE 214 AA; 23716 MW; EB51E9D9CE8543E5 CRC64;
MKAVFITGTD TDVGKTFVSA LLTKAWDANY WKPIQTGLES CQGDTETVKQ LTNFPEDRFE
RPQVELDIPL SPWRAALKEN KPQIEVSEIK IPPKYLNSSK PLIIEGAGGL FVPINETEIT
TDLILHLDIP VILVARSGLG TINHTLLSLE HLKNRGINKV FVVMNGPINK DNAEAIEKFS
KGIKIIANIP HSKPNDIVSL LKYVPSLDSI EIIN
//
