ID C5MIX3_CANTT Unreviewed; 1694 AA.
AC C5MIX3;
DT 28-JUL-2009, integrated into UniProtKB/TrEMBL.
DT 28-JUL-2009, sequence version 1.
DT 27-MAR-2024, entry version 51.
DE RecName: Full=PH domain-containing protein {ECO:0000259|PROSITE:PS50003};
GN ORFNames=CTRG_06016 {ECO:0000313|EMBL:EER30232.1};
OS Candida tropicalis (strain ATCC MYA-3404 / T1) (Yeast).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC Saccharomycetales; Debaryomycetaceae; Candida/Lodderomyces clade; Candida.
OX NCBI_TaxID=294747 {ECO:0000313|EMBL:EER30232.1, ECO:0000313|Proteomes:UP000002037};
RN [1] {ECO:0000313|EMBL:EER30232.1, ECO:0000313|Proteomes:UP000002037}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC MYA-3404 / T1 {ECO:0000313|Proteomes:UP000002037};
RX PubMed=19465905; DOI=10.1038/nature08064;
RA Butler G., Rasmussen M.D., Lin M.F., Santos M.A., Sakthikumar S.,
RA Munro C.A., Rheinbay E., Grabherr M., Forche A., Reedy J.L., Agrafioti I.,
RA Arnaud M.B., Bates S., Brown A.J., Brunke S., Costanzo M.C.,
RA Fitzpatrick D.A., de Groot P.W., Harris D., Hoyer L.L., Hube B., Klis F.M.,
RA Kodira C., Lennard N., Logue M.E., Martin R., Neiman A.M., Nikolaou E.,
RA Quail M.A., Quinn J., Santos M.C., Schmitzberger F.F., Sherlock G.,
RA Shah P., Silverstein K.A., Skrzypek M.S., Soll D., Staggs R.,
RA Stansfield I., Stumpf M.P., Sudbery P.E., Srikantha T., Zeng Q., Berman J.,
RA Berriman M., Heitman J., Gow N.A., Lorenz M.C., Birren B.W., Kellis M.,
RA Cuomo C.A.;
RT "Evolution of pathogenicity and sexual reproduction in eight Candida
RT genomes.";
RL Nature 459:657-662(2009).
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DR EMBL; GG692405; EER30232.1; -; Genomic_DNA.
DR RefSeq; XP_002546538.1; XM_002546492.1.
DR STRING; 294747.C5MIX3; -.
DR EnsemblFungi; CTRG_06016-t43_1; CTRG_06016-t43_1-p1; CTRG_06016.
DR GeneID; 8298587; -.
DR KEGG; ctp:CTRG_06016; -.
DR VEuPathDB; FungiDB:CTRG_06016; -.
DR eggNOG; ENOG502REBM; Eukaryota.
DR HOGENOM; CLU_240532_0_0_1; -.
DR OrthoDB; 2788168at2759; -.
DR Proteomes; UP000002037; Unassembled WGS sequence.
DR GO; GO:0007049; P:cell cycle; IEA:UniProtKB-KW.
DR GO; GO:0051301; P:cell division; IEA:UniProtKB-KW.
DR CDD; cd13278; PH_Bud4; 1.
DR Gene3D; 2.30.29.30; Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB); 1.
DR InterPro; IPR011993; PH-like_dom_sf.
DR InterPro; IPR001849; PH_domain.
DR PANTHER; PTHR36100; BUD SITE SELECTION PROTEIN 4; 1.
DR PANTHER; PTHR36100:SF1; BUD SITE SELECTION PROTEIN 4; 1.
DR Pfam; PF00169; PH; 1.
DR SMART; SM00233; PH; 1.
DR SUPFAM; SSF50729; PH domain-like; 1.
DR PROSITE; PS50003; PH_DOMAIN; 1.
PE 4: Predicted;
KW Cell cycle {ECO:0000256|ARBA:ARBA00023306};
KW Cell division {ECO:0000256|ARBA:ARBA00022618};
KW Reference proteome {ECO:0000313|Proteomes:UP000002037}.
FT DOMAIN 1564..1673
FT /note="PH"
FT /evidence="ECO:0000259|PROSITE:PS50003"
FT REGION 1..89
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 137..169
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 208..234
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 326..380
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 456..553
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 566..708
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 921..940
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1112..1225
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1290..1331
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 13..89
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 326..376
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 456..476
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 499..543
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 570..584
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 593..613
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 614..632
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 633..653
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 691..708
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1129..1178
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1311..1326
FT /note="Basic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1694 AA; 192284 MW; 2BB21EEA80A45FE5 CRC64;
MNLDPDKLVE NPNMQHELSS IFNSPTKPLN FPRTNSKPLL DPNSSSDTYT SDQEETKLPK
QQQQEQHQPQ EEQQEQQQEN PQSSFDRNFD IDNSIDLQQT INQDNTPTTE STTTFGNIID
EFSFQTPMTS TVDLLNNDEN TNDNQRPTYI NTSPSKSIMK KTPTASPKKV AFTSTIPEVH
HYPDNRLESD EQPVPILLPT IQHSWKAPEF NYSDDDTNGS VPPTPPPHTS KPTFAELLNR
NSTQESTASS DEPTLTHLNL EQDNYSNLSL DEKVNLYLDN DSNNNHKNVS DLDTHLQELQ
EASKNKTQES IHQLSFSLQT PKTEIENPLN SLASPDVQLR SSGSSQSSLQ SLRDNNRTLE
SVPGSPTKSN RGLSLNDGIK GLSDDVVESL LPRDESEEML NMRTISVHRR TLSSDDQLDS
FDRSYNKTEE SILNLLNSGS HSQLSLNKLE AGNDELQEKQ LPSEEEQERE DEPQGGINQM
EDADVPPPPP QQQEEPVKLK LEPGLELKTK RLVSNEVTEP VRLKKEPGTY EAEEEREQQR
VSDPNIKQEY STPCLLKREI PPHVSEITGL TPQEEINQYK SEHNIPISKE ADESMVSESS
ASRMSIQFNV ENEWRLEDSN DGDREDNDEM SRMENSQVLG DVSNSSTDTA DYRDASSELI
LQKTLAPPRT PTRGSIPGTP TPRRDTSEET VKPTPQQQVD ATEQAEEDNS QIIANSSNIA
PPEEITLPLV EQNDYSSFNE ITKNMNTYSS FEESLSAEND VDTKPVSFIS IWHKQEKQKK
SQMHKIPTQQ IIADCQELKQ KEDERRMSTD HVRIPSNLQT RKFKEVNVMS RRVVSPDMYD
LQVSEFLPEL SEDSGFNNLN FANYTSSRRR SFTPLSTKNV LSNIDNDPNV IEPPEPKSYS
EIKRARRLSS NQLAENQHSY VHNEPHHPQQ YAPASDYSTK RTSRFRVPTF EIKRTSSALS
PRDMYNDIFD DFGRSTAAMK GPPTIKADGM RTLPSMDKDD VKRILSAKKG ITQEEYINAK
LIDQEQPRKS VVTNSDTRYD DLQQTASIHN ATFESSPSRQ ISNNVGTNDN EILPYLTDEL
KKSPMALLSA NQIFNEHDAY PSRTSSVLFR PSANSSVLPE PDFELINSPE KCTSKSTSPE
TLQTSPLRLG SDTTHDGLNL SEKGSEQHLP TLDDLSPSTI KNDIKDEVST NDPPIEEPAT
PIQEMSPQKS VLSPKSPRKS PIKIGSPMKL VKKNGSITGM EPILKTHRAT KSFEGNEIMN
NKLRDGPTSP LFEKENDQHI PSTVTVPSEY TDAVSNPEDL QDVKSEEPKK NHHSYHHHHH
HHDHHHKNQV GSELPVVDDE SPDIGFEERG KLFFRVLGFK NINLPDIGIH NGKFSLTLDN
GVHSVTTPSY NLDGHKVPIG KEFELTVTDT LEFILTMKMS YEKPKGKLVE VTERKVVKSK
HRLSRLFGSK DIITTTKFVP TEVKDTWANK FAQDGSFARC YIDLQQFEDK ITGKALQFDL
NCFNEWETRV SNPNDHGINR LKPYTIGQLE VKMLFVPRSD PKEVLPTSIR TAYESIDELN
QEFNTTHEGY LHQEGGDCPI FKRRFFKLQG TSLLAHSEMS HKTRAKINLS KVVDIIYVDK
ENINRSKYRN FSDVLLVEHS FKIKFANGEL IDFCAPNKKE MKQWIDILES IVYRNRFRRQ
PWVKLMIQEN SNHV
//
