GenomeNet

Database: UniProt
Entry: C5NVU9_9BACL
LinkDB: C5NVU9_9BACL
Original site: C5NVU9_9BACL 
ID   C5NVU9_9BACL            Unreviewed;       494 AA.
AC   C5NVU9;
DT   01-SEP-2009, integrated into UniProtKB/TrEMBL.
DT   01-SEP-2009, sequence version 1.
DT   25-OCT-2017, entry version 55.
DE   RecName: Full=Chromosomal replication initiator protein DnaA {ECO:0000256|HAMAP-Rule:MF_00377, ECO:0000256|RuleBase:RU000577};
GN   Name=dnaA {ECO:0000256|HAMAP-Rule:MF_00377,
GN   ECO:0000313|EMBL:EER68783.1};
GN   ORFNames=GEMHA0001_1015 {ECO:0000313|EMBL:EER68783.1};
OS   Gemella haemolysans ATCC 10379.
OC   Bacteria; Firmicutes; Bacilli; Bacillales;
OC   Bacillales Family XI. Incertae Sedis; Gemella.
OX   NCBI_TaxID=546270 {ECO:0000313|EMBL:EER68783.1, ECO:0000313|Proteomes:UP000006004};
RN   [1] {ECO:0000313|EMBL:EER68783.1, ECO:0000313|Proteomes:UP000006004}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 10379 {ECO:0000313|EMBL:EER68783.1,
RC   ECO:0000313|Proteomes:UP000006004};
RA   Fulton L., Clifton S., Chinwalla A.T., Mitreva M., Sodergren E.,
RA   Weinstock G., Clifton S., Dooling D.J., Fulton B., Minx P.,
RA   Pepin K.H., Johnson M., Bhonagiri V., Nash W.E., Mardis E.R.,
RA   Wilson R.K.;
RL   Submitted (JAN-2009) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|EMBL:EER68783.1, ECO:0000313|Proteomes:UP000006004}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 10379 {ECO:0000313|EMBL:EER68783.1,
RC   ECO:0000313|Proteomes:UP000006004};
RA   Sebastian Y., Madupu R., Durkin A.S., Torralba M., Methe B.,
RA   Sutton G.G., Strausberg R.L., Nelson K.E.;
RL   Submitted (JUN-2009) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Plays an important role in the initiation and regulation
CC       of chromosomal replication. Binds to the origin of replication; it
CC       binds specifically double-stranded DNA at a 9 bp consensus (dnaA
CC       box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic
CC       phospholipids. {ECO:0000256|HAMAP-Rule:MF_00377,
CC       ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00735475}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|HAMAP-Rule:MF_00377,
CC       ECO:0000256|SAAS:SAAS00911680}.
CC   -!- SIMILARITY: Belongs to the DnaA family. {ECO:0000256|HAMAP-
CC       Rule:MF_00377, ECO:0000256|RuleBase:RU004227,
CC       ECO:0000256|SAAS:SAAS00555179}.
CC   -!- CAUTION: The sequence shown here is derived from an
CC       EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is
CC       preliminary data. {ECO:0000313|EMBL:EER68783.1}.
CC   -----------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution-NoDerivs License
CC   -----------------------------------------------------------------------
DR   EMBL; ACDZ02000008; EER68783.1; -; Genomic_DNA.
DR   RefSeq; WP_003144416.1; NZ_ACDZ02000008.1.
DR   ProteinModelPortal; C5NVU9; -.
DR   STRING; 546270.GEMHA0001_1015; -.
DR   EnsemblBacteria; EER68783; EER68783; GEMHA0001_1015.
DR   eggNOG; ENOG4105CI4; Bacteria.
DR   eggNOG; COG0593; LUCA.
DR   OrthoDB; POG091H02FF; -.
DR   Proteomes; UP000006004; Unassembled WGS sequence.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0003688; F:DNA replication origin binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0006270; P:DNA replication initiation; IEA:UniProtKB-UniRule.
DR   GO; GO:0006275; P:regulation of DNA replication; IEA:UniProtKB-UniRule.
DR   CDD; cd06571; Bac_DnaA_C; 1.
DR   Gene3D; 1.10.1750.10; -; 1.
DR   HAMAP; MF_00377; DnaA_bact; 1.
DR   InterPro; IPR003593; AAA+_ATPase.
DR   InterPro; IPR001957; Chromosome_initiator_DnaA.
DR   InterPro; IPR020591; Chromosome_initiator_DnaA-like.
DR   InterPro; IPR018312; Chromosome_initiator_DnaA_CS.
DR   InterPro; IPR013317; DnaA.
DR   InterPro; IPR013159; DnaA_C.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR010921; Trp_repressor/repl_initiator.
DR   PANTHER; PTHR30050:SF2; PTHR30050:SF2; 1.
DR   Pfam; PF00308; Bac_DnaA; 1.
DR   Pfam; PF08299; Bac_DnaA_C; 1.
DR   PRINTS; PR00051; DNAA.
DR   SMART; SM00382; AAA; 1.
DR   SMART; SM00760; Bac_DnaA_C; 1.
DR   SUPFAM; SSF48295; SSF48295; 1.
DR   SUPFAM; SSF52540; SSF52540; 1.
DR   TIGRFAMs; TIGR00362; DnaA; 1.
DR   PROSITE; PS01008; DNAA; 1.
PE   3: Inferred from homology;
KW   ATP-binding {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00747950};
KW   Complete proteome {ECO:0000313|Proteomes:UP000006004};
KW   Cytoplasm {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|SAAS:SAAS00911664};
KW   DNA replication {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU004227, ECO:0000256|SAAS:SAAS00747996};
KW   DNA-binding {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00911684};
KW   Nucleotide-binding {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00747895};
KW   Reference proteome {ECO:0000313|Proteomes:UP000006004}.
FT   DOMAIN      182    323       AAA. {ECO:0000259|SMART:SM00382}.
FT   DOMAIN      401    469       Bac_DnaA_C. {ECO:0000259|SMART:SM00760}.
FT   NP_BIND     190    197       ATP. {ECO:0000256|HAMAP-Rule:MF_00377}.
SQ   SEQUENCE   494 AA;  56434 MW;  D1E1FD5F3D3E5485 CRC64;
     MSNSNFLWEI ILRELKSTVD PHVFDTWFSG ASIDNVDFMK KSIVITSKEA LISQFIQGAY
     DQKLKEILKK NTGFDFNIDY TSLDTDIPLI TPQVFDEKPA AENLIRQNFL QGDKPSGAQH
     FYQKQTFPLE DYKHPVPNKN ITASKKNPTL NKNYTFENFV VGEGNAFTHN IAWNVAVSPG
     GIYNPLFIYG GVGLGKTHLL HAIGNEMEAN FPDFKIECIS SEKFLNEFLA SIKPMKDKNN
     YTNADEDFRR KYRDVDALLI DDIQFLSGKT ETQNAFFHTF NELQMNQKQI VLISDRSPSQ
     LNDLEDRLVT RFSQGITADI TPPDFETRMA IIKFKCEQFD IKLDEETLTY ISSNVSSNIR
     ELEGVLKRIK FTATSKHEQP SLSIAEEILK SAKTSPRKNI SPDNIINVCA DFYKIKVDDI
     LSSSRKKEVV QVRNIAIYLC RELTTLSFPS IGDCFNKDHT SILYSFNKIA KLSKDENPEI
     FEDIEVIKER LGKI
//
DBGET integrated database retrieval system