ID C5P566_COCP7 Unreviewed; 549 AA.
AC C5P566;
DT 01-SEP-2009, integrated into UniProtKB/TrEMBL.
DT 01-SEP-2009, sequence version 1.
DT 24-JAN-2024, entry version 65.
DE SubName: Full=Serine O-acetyltransferase, putative {ECO:0000313|EMBL:EER27856.1};
GN ORFNames=CPC735_031920 {ECO:0000313|EMBL:EER27856.1};
OS Coccidioides posadasii (strain C735) (Valley fever fungus).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Eurotiomycetidae; Onygenales; Onygenaceae; Coccidioides.
OX NCBI_TaxID=222929 {ECO:0000313|EMBL:EER27856.1, ECO:0000313|Proteomes:UP000009084};
RN [1] {ECO:0000313|EMBL:EER27856.1, ECO:0000313|Proteomes:UP000009084}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=C735 {ECO:0000313|Proteomes:UP000009084};
RX PubMed=19717792; DOI=10.1101/gr.087551.108;
RA Sharpton T.J., Stajich J.E., Rounsley S.D., Gardner M.J., Wortman J.R.,
RA Jordar V.S., Maiti R., Kodira C.D., Neafsey D.E., Zeng Q., Hung C.-Y.,
RA McMahan C., Muszewska A., Grynberg M., Mandel M.A., Kellner E.M.,
RA Barker B.M., Galgiani J.N., Orbach M.J., Kirkland T.N., Cole G.T.,
RA Henn M.R., Birren B.W., Taylor J.W.;
RT "Comparative genomic analyses of the human fungal pathogens Coccidioides
RT and their relatives.";
RL Genome Res. 19:1722-1731(2009).
CC -!- SIMILARITY: Belongs to the AB hydrolase superfamily. MetX family.
CC {ECO:0000256|ARBA:ARBA00006886}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EER27856.1}.
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DR EMBL; ACFW01000025; EER27856.1; -; Genomic_DNA.
DR RefSeq; XP_003070001.1; XM_003069955.1.
DR AlphaFoldDB; C5P566; -.
DR GeneID; 9695496; -.
DR KEGG; cpw:CPC735_031920; -.
DR VEuPathDB; FungiDB:CPC735_031920; -.
DR HOGENOM; CLU_028760_7_0_1; -.
DR OrthoDB; 63733at2759; -.
DR Proteomes; UP000009084; Unassembled WGS sequence.
DR GO; GO:0016747; F:acyltransferase activity, transferring groups other than amino-acyl groups; IEA:InterPro.
DR GO; GO:0009058; P:biosynthetic process; IEA:InterPro.
DR Gene3D; 3.40.50.1820; alpha/beta hydrolase; 1.
DR HAMAP; MF_00296; MetX_acyltransf; 1.
DR InterPro; IPR029058; AB_hydrolase.
DR InterPro; IPR000073; AB_hydrolase_1.
DR InterPro; IPR008220; HAT_MetX-like.
DR NCBIfam; TIGR01392; homoserO_Ac_trn; 1.
DR PANTHER; PTHR32268; HOMOSERINE O-ACETYLTRANSFERASE; 1.
DR PANTHER; PTHR32268:SF16; SERINE O-SUCCINYLTRANSFERASE; 1.
DR Pfam; PF00561; Abhydrolase_1; 1.
DR PIRSF; PIRSF000443; Homoser_Ac_trans; 1.
DR SUPFAM; SSF53474; alpha/beta-Hydrolases; 1.
PE 3: Inferred from homology;
KW Transferase {ECO:0000313|EMBL:EER27856.1}.
FT DOMAIN 153..508
FT /note="AB hydrolase-1"
FT /evidence="ECO:0000259|Pfam:PF00561"
FT REGION 395..465
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 402..416
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 446..465
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 549 AA; 60155 MW; 880D4E11220DF1B7 CRC64;
MRAATRRAAL RPSAAVWSRN LEFHGQASRF WGPAPVLASA STSSTHLGRR SIQSHRPNRA
AQAIAASREP SEQRTYDSSN PALSFPCLDA LEAKSALLSA RSLSSGPEPS YTTGHHEQFR
SREPLLLDWG GVLPEFEIAY ETWGTLNSQR SNAILLHTGL SASSHAHSTK ANPKPGWWEK
FIGPGAPLDT NKYFVICTNV IGGCFGSTGP SSIDPSDGKR YATRFPILTL DDMVRAQFRL
LDSLGVSKLY ASVGSSMGGM QSLAAGVLFP ERVGRIVSIS GCARSHPYSI AMRHTQRQVL
MMDPNWARGF YYDSIPPHSG MKLAREIATV TYRSGPEWEK RFGRARADPS KQPALCPDFL
IETYLDHAGE KFSLDYDPNS LLYVSKAMDL FDLSRSQQQA TRQRRVKNEE RISSSSRPPH
NDPSCSLTLP AKPYEEQPAE LSDLASADES ISSADSASSP SSSFQLFQPP PDLVAGLTPL
KDHPILVMGV ASDILFPAWQ QREIADSLRA AGSEKVKHVE LGEDVSLFGH DTFLLDLKNI
GGPIQQFLQ
//
