ID C5PGY4_COCP7 Unreviewed; 1307 AA.
AC C5PGY4;
DT 01-SEP-2009, integrated into UniProtKB/TrEMBL.
DT 01-SEP-2009, sequence version 1.
DT 27-MAR-2024, entry version 56.
DE SubName: Full=KH domain containing protein {ECO:0000313|EMBL:EER23787.1};
GN ORFNames=CPC735_051570 {ECO:0000313|EMBL:EER23787.1};
OS Coccidioides posadasii (strain C735) (Valley fever fungus).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Eurotiomycetidae; Onygenales; Onygenaceae; Coccidioides.
OX NCBI_TaxID=222929 {ECO:0000313|EMBL:EER23787.1, ECO:0000313|Proteomes:UP000009084};
RN [1] {ECO:0000313|EMBL:EER23787.1, ECO:0000313|Proteomes:UP000009084}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=C735 {ECO:0000313|Proteomes:UP000009084};
RX PubMed=19717792; DOI=10.1101/gr.087551.108;
RA Sharpton T.J., Stajich J.E., Rounsley S.D., Gardner M.J., Wortman J.R.,
RA Jordar V.S., Maiti R., Kodira C.D., Neafsey D.E., Zeng Q., Hung C.-Y.,
RA McMahan C., Muszewska A., Grynberg M., Mandel M.A., Kellner E.M.,
RA Barker B.M., Galgiani J.N., Orbach M.J., Kirkland T.N., Cole G.T.,
RA Henn M.R., Birren B.W., Taylor J.W.;
RT "Comparative genomic analyses of the human fungal pathogens Coccidioides
RT and their relatives.";
RL Genome Res. 19:1722-1731(2009).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EER23787.1}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; ACFW01000049; EER23787.1; -; Genomic_DNA.
DR RefSeq; XP_003065932.1; XM_003065886.1.
DR GeneID; 9691402; -.
DR KEGG; cpw:CPC735_051570; -.
DR VEuPathDB; FungiDB:CPC735_051570; -.
DR HOGENOM; CLU_003293_0_0_1; -.
DR OrthoDB; 5489311at2759; -.
DR Proteomes; UP000009084; Unassembled WGS sequence.
DR GO; GO:0003723; F:RNA binding; IEA:UniProtKB-UniRule.
DR CDD; cd22448; KH-I_ScSCP160_rpt3; 1.
DR CDD; cd22408; KH-I_Vigilin_rpt4; 1.
DR CDD; cd02394; KH-I_Vigilin_rpt6; 1.
DR Gene3D; 3.30.1370.10; K Homology domain, type 1; 9.
DR InterPro; IPR004087; KH_dom.
DR InterPro; IPR004088; KH_dom_type_1.
DR InterPro; IPR036612; KH_dom_type_1_sf.
DR PANTHER; PTHR10627:SF69; PROTEIN BICAUDAL C; 1.
DR PANTHER; PTHR10627; SCP160; 1.
DR Pfam; PF00013; KH_1; 8.
DR SMART; SM00322; KH; 10.
DR SUPFAM; SSF54791; Eukaryotic type KH-domain (KH-domain type I); 8.
DR PROSITE; PS50084; KH_TYPE_1; 8.
PE 4: Predicted;
KW RNA-binding {ECO:0000256|PROSITE-ProRule:PRU00117}.
FT DOMAIN 231..309
FT /note="K Homology"
FT /evidence="ECO:0000259|SMART:SM00322"
FT DOMAIN 313..402
FT /note="K Homology"
FT /evidence="ECO:0000259|SMART:SM00322"
FT DOMAIN 407..475
FT /note="K Homology"
FT /evidence="ECO:0000259|SMART:SM00322"
FT DOMAIN 723..786
FT /note="K Homology"
FT /evidence="ECO:0000259|SMART:SM00322"
FT DOMAIN 790..880
FT /note="K Homology"
FT /evidence="ECO:0000259|SMART:SM00322"
FT DOMAIN 885..958
FT /note="K Homology"
FT /evidence="ECO:0000259|SMART:SM00322"
FT DOMAIN 962..1038
FT /note="K Homology"
FT /evidence="ECO:0000259|SMART:SM00322"
FT DOMAIN 1042..1110
FT /note="K Homology"
FT /evidence="ECO:0000259|SMART:SM00322"
FT DOMAIN 1111..1224
FT /note="K Homology"
FT /evidence="ECO:0000259|SMART:SM00322"
FT DOMAIN 1229..1298
FT /note="K Homology"
FT /evidence="ECO:0000259|SMART:SM00322"
FT REGION 1..83
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 121..154
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1146..1166
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 25..51
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 127..146
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1307 AA; 143256 MW; 7854FAC73E102A5F CRC64;
MASEQPGLIV NGGTAAAASK SPAELLQEKH ARDEAHQPTI EEVRDEEDVL HPPPSSATAE
PAPASWKDTA AKDEAANSVP KSKIVPFDVK CEELFPALGS GSKSRVPAAM PMAWDGRKAA
APSAGLANGG SRSSVPSRTS TPTSGVAAPL GGPRLAMPGK HVEQIRFAPS QMLPRSKLSK
PLADIVRDIS RKSKARLDVR EGPGGSYIFE GTGTVDAVRQ ALKEVAQQVG SKQSVRIPVP
ASTRPHIIGR QGTVVQGIHD RTGARIQVPK PDDSTLQDED DDSNTIDVLI EGDAVAAEMA
RREIEAIVKE RTSSINLKLK NIPPELFPFI AGAHNSHLND LEERTKTQVR VPRYDTWSKR
PPPQEAPVGQ IQFTADPDRH IHVFGDRMGA QEARAEIERR ALELERQIGL RHLAINRGQH
QFIIGDKGHS LHDFLAETGC SVILPPPSDA TEFLTVIGPP DKIETGINRV MDLATSMQMA
SIDISRQHLN APSGPHAYAQ ALTMYLQQRQ IVRDLERMHN AHIVLPLLTS SGPVVWEVYS
RDGRNTILAR SDILNLVQAH PPSKLATLSV DPYYHDFLRS RSAPVLKEKY GVYLVVPNNS
ETSDILLVCE GPDQTEVPRQ RPSTEEIAAF QRALNEAQTY LLSSLGDQSN IVSKSVPVPS
KYHDKLRKFV AREESAKGED HIPVRMLVAD QQASLRGRSR DVQDLVPKII AFVQEQEQDE
KERDNKISFE FPQKFANVLI GRKGENINKL RDEFDVDIKV ENGKVEVKGP PTKANAAKAR
IIALAKKMED ETTYVLKIAP QYHRDLIGQK GSQVNRLQER YNVRVQFPRA ASLDESVNDA
ASEAGSVRNT RSNQAPDEVV IRGPRKGADG AREEILSLYQ WVADHSYTGS VSVSQSQIPS
LIGQRGREMD KLRTETGAQI DVPSVNDVAD ASGRVEIKLK GTKKQVEDAR KLLLQRAKEF
DETVTKAIDV DKKHHKSLIG GGGANIRKIV VECGGPDDGT AARIVRFPRP ESDDSSIRLE
GKEVIVDKII AAIQEFVRQK EDEVVSSIDV PQSQHRHLIG RGGDTRRQLE TQFNVVLDVP
KQGSNRTDVK IRGPSSFVEN AKTHILAMLK EQQGETVNVP RSLHHAISEN GSFFRRLRND
HQVTVDHAGE QIPPRPSPTK SRDADDVGSL PLITDDPAAA TDAFSWKVVD SSNDDVPAGT
IPWVLSGKPE NVAKARALLE KAILTASQPS ATGYLILPDP RTYRFVIGPN GSQINAIRKR
TNCKINVPKD QARDEAIEIK GSKESLELAK DMILDAVKVG TSGNGRA
//
