ID   C5PIF0_COCP7            Unreviewed;       719 AA.
AC   C5PIF0;
DT   01-SEP-2009, integrated into UniProtKB/TrEMBL.
DT   01-SEP-2009, sequence version 1.
DT   24-JAN-2024, entry version 64.
DE   SubName: Full=Zinc finger, C3HC4 type (RING finger) containing protein {ECO:0000313|EMBL:EER24303.1};
GN   ORFNames=CPC735_056730 {ECO:0000313|EMBL:EER24303.1};
OS   Coccidioides posadasii (strain C735) (Valley fever fungus).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC   Eurotiomycetidae; Onygenales; Onygenaceae; Coccidioides.
OX   NCBI_TaxID=222929 {ECO:0000313|EMBL:EER24303.1, ECO:0000313|Proteomes:UP000009084};
RN   [1] {ECO:0000313|EMBL:EER24303.1, ECO:0000313|Proteomes:UP000009084}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=C735 {ECO:0000313|Proteomes:UP000009084};
RX   PubMed=19717792; DOI=10.1101/gr.087551.108;
RA   Sharpton T.J., Stajich J.E., Rounsley S.D., Gardner M.J., Wortman J.R.,
RA   Jordar V.S., Maiti R., Kodira C.D., Neafsey D.E., Zeng Q., Hung C.-Y.,
RA   McMahan C., Muszewska A., Grynberg M., Mandel M.A., Kellner E.M.,
RA   Barker B.M., Galgiani J.N., Orbach M.J., Kirkland T.N., Cole G.T.,
RA   Henn M.R., Birren B.W., Taylor J.W.;
RT   "Comparative genomic analyses of the human fungal pathogens Coccidioides
RT   and their relatives.";
RL   Genome Res. 19:1722-1731(2009).
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:EER24303.1}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; ACFW01000049; EER24303.1; -; Genomic_DNA.
DR   RefSeq; XP_003066448.1; XM_003066402.1.
DR   AlphaFoldDB; C5PIF0; -.
DR   GeneID; 9691918; -.
DR   KEGG; cpw:CPC735_056730; -.
DR   VEuPathDB; FungiDB:CPC735_056730; -.
DR   HOGENOM; CLU_009969_0_0_1; -.
DR   OrthoDB; 123540at2759; -.
DR   Proteomes; UP000009084; Unassembled WGS sequence.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   CDD; cd16457; RING-H2_BRAP2; 1.
DR   CDD; cd12717; RRM_ETP1; 1.
DR   Gene3D; 3.30.40.10; Zinc/RING finger domain, C3HC4 (zinc finger); 2.
DR   InterPro; IPR011422; BRAP2/ETP1_RRM.
DR   InterPro; IPR034931; ETP1_RRM.
DR   InterPro; IPR047243; RING-H2_BRAP2.
DR   InterPro; IPR001841; Znf_RING.
DR   InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR   InterPro; IPR001607; Znf_UBP.
DR   PANTHER; PTHR24007; BRCA1-ASSOCIATED PROTEIN; 1.
DR   PANTHER; PTHR24007:SF7; BRCA1-ASSOCIATED PROTEIN; 1.
DR   Pfam; PF07576; BRAP2; 1.
DR   Pfam; PF13639; zf-RING_2; 1.
DR   Pfam; PF02148; zf-UBP; 1.
DR   SMART; SM00184; RING; 1.
DR   SMART; SM00290; ZnF_UBP; 1.
DR   SUPFAM; SSF57850; RING/U-box; 1.
DR   PROSITE; PS50089; ZF_RING_2; 1.
DR   PROSITE; PS50271; ZF_UBP; 1.
PE   4: Predicted;
KW   Coiled coil {ECO:0000256|SAM:Coils};
KW   Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW   Zinc {ECO:0000256|ARBA:ARBA00022833};
KW   Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW   ProRule:PRU00502}.
FT   DOMAIN          389..428
FT                   /note="RING-type"
FT                   /evidence="ECO:0000259|PROSITE:PS50089"
FT   DOMAIN          422..526
FT                   /note="UBP-type"
FT                   /evidence="ECO:0000259|PROSITE:PS50271"
FT   REGION          38..89
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          225..249
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          690..719
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COILED          584..678
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COMPBIAS        38..79
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   719 AA;  79963 MW;  40D394786F6A48AA CRC64;
     MPSYFYRICL ELFCENSSSN LLTVEAICES LNPFSRKQLN SKKSAPNNRS APTRINQNLK
     SSELYPAKDY NSSVTNAPRQ CLPAGEPSRS HNYLQRVEHA PVNYSTSGGK ETSPASPFLT
     SLARQTCDRR VDTISVEGID MVLEKAHLPD RSSGPDNNQI AKGIGSRAIG GLATKGKYVP
     LDHKVPNSVW GIVHLYRDGD PSPELCGNDD DPYFLKGSSV ARNTSVSSPR IKKSQGSTFG
     DESSDPSLSA EDCTTLCILA VPSYMSPPDF IGWVGQETKS EVSHFRMIRT ERRNRYMVLM
     KFRSGRKARE WQKDWNGKVF NSTEPETCHV VFVKDVEIQT PTTSPEGRFP DTNHDPFTPQ
     AYASTVATAS LSIKPLAPPT PSLIELPTCP VCLERMDETS GLLTIICQHV FHCTCLQKWK
     GSGCPVCRYT QEDLGKRAFN FGLDEGPAEC SVCHAEENLW ICLICGNIGC GRYDGAHAFA
     HFQETSHSFA MDLSSQRVWD YVGDGYVHRI IQNKADGKLL ELPAADNSAL DPPDWADAVP
     REKWENMSVE YTHLLTSQLE SQRTYFEEKV ERAADKASQA SAAALAAQEA AEKLAKRLEA
     LQCDHDALVK ETVPVLEKEK DRAERRADKF ESLARKMEKE YREEKTINTS LMERVDYLTA
     EVEKLKAANE DLAEQNRDLT FFISGSEKLK DQGEDVVEGT VSVPEPSKAG KKKKGKGKK
//