ID C5QQQ4_9STAP Unreviewed; 142 AA.
AC C5QQQ4;
DT 01-SEP-2009, integrated into UniProtKB/TrEMBL.
DT 01-SEP-2009, sequence version 1.
DT 27-MAR-2024, entry version 45.
DE RecName: Full=Na(+)/H(+) antiporter subunit B1 {ECO:0000256|ARBA:ARBA00018332, ECO:0000256|RuleBase:RU368067};
DE AltName: Full=Mnh complex subunit B1 {ECO:0000256|ARBA:ARBA00031664, ECO:0000256|RuleBase:RU368067};
GN Name=mnhB {ECO:0000313|EMBL:EES40873.1};
GN ORFNames=HMPREF0793_1560 {ECO:0000313|EMBL:EES40873.1};
OS Staphylococcus caprae M23864:W1.
OC Bacteria; Bacillota; Bacilli; Bacillales; Staphylococcaceae;
OC Staphylococcus.
OX NCBI_TaxID=525378 {ECO:0000313|EMBL:EES40873.1, ECO:0000313|Proteomes:UP000003152};
RN [1] {ECO:0000313|EMBL:EES40873.1, ECO:0000313|Proteomes:UP000003152}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=M23864:W1 {ECO:0000313|EMBL:EES40873.1,
RC ECO:0000313|Proteomes:UP000003152};
RA Qin X., Bachman B., Battles P., Bell A., Bess C., Bickham C., Chaboub L.,
RA Chen D., Coyle M., Deiros D.R., Dinh H., Forbes L., Fowler G.,
RA Francisco L., Fu Q., Gubbala S., Hale W., Han Y., Hemphill L.,
RA Highlander S.K., Hirani K., Hogues M., Jackson L., Jakkamsetti A.,
RA Javaid M., Jiang H., Korchina V., Kovar C., Lara F., Lee S., Mata R.,
RA Mathew T., Moen C., Morales K., Munidasa M., Nazareth L., Ngo R.,
RA Nguyen L., Okwuonu G., Ongeri F., Patil S., Petrosino J., Pham C., Pham P.,
RA Pu L.-L., Puazo M., Raj R., Reid J., Rouhana J., Saada N., Shang Y.,
RA Simmons D., Thornton R., Warren J., Weissenberger G., Zhang J., Zhang L.,
RA Zhou C., Zhu D., Muzny D., Worley K., Gibbs R.;
RL Submitted (JAN-2009) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Mnh complex is a Na(+)/H(+) antiporter involved in Na(+)
CC excretion. {ECO:0000256|RuleBase:RU368067}.
CC -!- SUBUNIT: May form a heterooligomeric complex that consists of seven
CC subunits: mnhA1, mnhB1, mnhC1, mnhD1, mnhE1, mnhF1 and mnhG1.
CC {ECO:0000256|ARBA:ARBA00011568, ECO:0000256|RuleBase:RU368067}.
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|ARBA:ARBA00004651,
CC ECO:0000256|RuleBase:RU368067}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004651, ECO:0000256|RuleBase:RU368067}.
CC Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the CPA3 antiporters (TC 2.A.63) subunit B
CC family. {ECO:0000256|ARBA:ARBA00009425, ECO:0000256|RuleBase:RU368067}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EES40873.1}.
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DR EMBL; ACJB01000053; EES40873.1; -; Genomic_DNA.
DR RefSeq; WP_002441786.1; NZ_GG696773.1.
DR AlphaFoldDB; C5QQQ4; -.
DR eggNOG; COG2111; Bacteria.
DR HOGENOM; CLU_101659_1_1_9; -.
DR Proteomes; UP000003152; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0015297; F:antiporter activity; IEA:UniProtKB-UniRule.
DR GO; GO:0008324; F:monoatomic cation transmembrane transporter activity; IEA:UniProtKB-UniRule.
DR GO; GO:1902600; P:proton transmembrane transport; IEA:UniProtKB-KW.
DR GO; GO:0006814; P:sodium ion transport; IEA:UniProtKB-UniRule.
DR InterPro; IPR005281; CPA3_sub_B.
DR InterPro; IPR007182; MnhB.
DR NCBIfam; TIGR00943; 2a6301s02; 1.
DR PANTHER; PTHR33932; NA(+)/H(+) ANTIPORTER SUBUNIT B; 1.
DR PANTHER; PTHR33932:SF4; NA(+)_H(+) ANTIPORTER SUBUNIT B1; 1.
DR Pfam; PF04039; MnhB; 1.
PE 3: Inferred from homology;
KW Antiport {ECO:0000256|ARBA:ARBA00022449, ECO:0000256|RuleBase:RU368067};
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475,
KW ECO:0000256|RuleBase:RU368067};
KW Hydrogen ion transport {ECO:0000256|RuleBase:RU368067};
KW Ion transport {ECO:0000256|RuleBase:RU368067};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|RuleBase:RU368067};
KW Sodium {ECO:0000256|ARBA:ARBA00023053};
KW Sodium transport {ECO:0000256|ARBA:ARBA00023201};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692,
KW ECO:0000256|RuleBase:RU368067};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|RuleBase:RU368067}; Transport {ECO:0000256|RuleBase:RU368067}.
FT TRANSMEM 12..34
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU368067"
FT TRANSMEM 40..59
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU368067"
FT TRANSMEM 71..91
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU368067"
FT TRANSMEM 111..138
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU368067"
FT DOMAIN 11..133
FT /note="Na+/H+ antiporter MnhB subunit-related protein"
FT /evidence="ECO:0000259|Pfam:PF04039"
SQ SEQUENCE 142 AA; 15720 MW; 9C19A9F10D3F94BD CRC64;
MNRQKNNLMF QYAAIVIFFM VIVFGFSLFL AGHYTPGGGF VGGLLFASAL LVITIAFDVK
TMRKVFPLDF KILIGVGLLF CVGTPIASWF MSKNFFTHVT FDIPLPLLEP MHMTTAMFFD
FGVLCAVVGT VMTIIISIGE NE
//
