ID C5X7U0_SORBI Unreviewed; 713 AA.
AC C5X7U0;
DT 01-SEP-2009, integrated into UniProtKB/TrEMBL.
DT 01-SEP-2009, sequence version 1.
DT 24-JAN-2024, entry version 73.
DE RecName: Full=Cyclic nucleotide-binding domain-containing protein {ECO:0000259|PROSITE:PS50042};
GN ORFNames=SORBI_3002G294800 {ECO:0000313|EMBL:EER97175.1};
OS Sorghum bicolor (Sorghum) (Sorghum vulgare).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; PACMAD clade;
OC Panicoideae; Andropogonodae; Andropogoneae; Sorghinae; Sorghum.
OX NCBI_TaxID=4558 {ECO:0000313|EMBL:EER97175.1, ECO:0000313|Proteomes:UP000000768};
RN [1] {ECO:0000313|EMBL:EER97175.1, ECO:0000313|Proteomes:UP000000768}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. BTx623 {ECO:0000313|Proteomes:UP000000768};
RX PubMed=19189423; DOI=10.1038/nature07723;
RA Paterson A.H., Bowers J.E., Bruggmann R., Dubchak I., Grimwood J.,
RA Gundlach H., Haberer G., Hellsten U., Mitros T., Poliakov A., Schmutz J.,
RA Spannagl M., Tang H., Wang X., Wicker T., Bharti A.K., Chapman J.,
RA Feltus F.A., Gowik U., Grigoriev I.V., Lyons E., Maher C.A., Martis M.,
RA Narechania A., Otillar R.P., Penning B.W., Salamov A.A., Wang Y., Zhang L.,
RA Carpita N.C., Freeling M., Gingle A.R., Hash C.T., Keller B., Klein P.,
RA Kresovich S., McCann M.C., Ming R., Peterson D.G., Mehboob-ur-Rahman,
RA Ware D., Westhoff P., Mayer K.F., Messing J., Rokhsar D.S.;
RT "The Sorghum bicolor genome and the diversification of grasses.";
RL Nature 457:551-556(2009).
RN [2] {ECO:0000313|Proteomes:UP000000768}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. BTx623 {ECO:0000313|Proteomes:UP000000768};
RX PubMed=29161754; DOI=10.1111/tpj.13781;
RA McCormick R.F., Truong S.K., Sreedasyam A., Jenkins J., Shu S., Sims D.,
RA Kennedy M., Amirebrahimi M., Weers B.D., McKinley B., Mattison A.,
RA Morishige D.T., Grimwood J., Schmutz J., Mullet J.E.;
RT "The Sorghum bicolor reference genome: improved assembly, gene annotations,
RT a transcriptome atlas, and signatures of genome organization.";
RL Plant J. 93:338-354(2018).
CC -!- SIMILARITY: Belongs to the cyclic nucleotide-gated cation channel (TC
CC 1.A.1.5) family. {ECO:0000256|ARBA:ARBA00010486}.
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DR EMBL; CM000761; EER97175.1; -; Genomic_DNA.
DR RefSeq; XP_002460654.1; XM_002460609.1.
DR AlphaFoldDB; C5X7U0; -.
DR STRING; 4558.C5X7U0; -.
DR EnsemblPlants; EER97175; EER97175; SORBI_3002G294800.
DR GeneID; 8074198; -.
DR Gramene; EER97175; EER97175; SORBI_3002G294800.
DR KEGG; sbi:8074198; -.
DR eggNOG; KOG0498; Eukaryota.
DR HOGENOM; CLU_013069_3_0_1; -.
DR InParanoid; C5X7U0; -.
DR OMA; EMQRRPN; -.
DR OrthoDB; 347012at2759; -.
DR Proteomes; UP000000768; Chromosome 2.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0005216; F:monoatomic ion channel activity; IEA:InterPro.
DR CDD; cd00038; CAP_ED; 1.
DR Gene3D; 1.10.287.70; -; 1.
DR Gene3D; 1.10.287.630; Helix hairpin bin; 1.
DR Gene3D; 2.60.120.10; Jelly Rolls; 1.
DR InterPro; IPR000595; cNMP-bd_dom.
DR InterPro; IPR018490; cNMP-bd_dom_sf.
DR InterPro; IPR005821; Ion_trans_dom.
DR InterPro; IPR014710; RmlC-like_jellyroll.
DR PANTHER; PTHR45651; CYCLIC NUCLEOTIDE-GATED ION CHANNEL 15-RELATED-RELATED; 1.
DR PANTHER; PTHR45651:SF7; OS09G0558300 PROTEIN; 1.
DR Pfam; PF00027; cNMP_binding; 1.
DR Pfam; PF00520; Ion_trans; 1.
DR SMART; SM00100; cNMP; 1.
DR SUPFAM; SSF51206; cAMP-binding domain-like; 1.
DR SUPFAM; SSF81324; Voltage-gated potassium channels; 1.
DR PROSITE; PS50042; CNMP_BINDING_3; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000000768};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 82..100
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 175..194
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 206..225
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 246..267
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 367..391
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 480..562
FT /note="Cyclic nucleotide-binding"
FT /evidence="ECO:0000259|PROSITE:PS50042"
FT REGION 1..27
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 648..673
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 713 AA; 82329 MW; 7F1BCCE719F86666 CRC64;
MFGSRVQDEV EMQRRPNNRI FPDERQNQSK PLYQTARADR FGANRMDLKN PEKLKVLNEG
NKPWHQRILD PGSNIVLRWN RVYLVACLFA LFIDPFFYYL PLIRKNGNVS SCVAKDQGLS
IRITVLRSLA DLFYMLNIAI KFHTAYVDPK SRVLGKGELV VDIKKIQRRY IRTDFFVDIL
AAVPLPQVTV WLIMPAIESS DYNIRNTTFA LVIVVQYFIR MYLIIPLSNQ IIKAVGVVAK
SAWGGAAYNL LLYMLASHIT GAIYYLLSVE RQITCWDQQC IAESNDTNCN LRFISCENSG
SDDYSVWAKN TSIFANCDAT NPNNISFNYG MFLSALGKGA VSSPFLEKYF FCLWWGLLQL
SSSGNPLITS AFITENLFAI AIGAISLILF AQLIGKMQTY LQSISKRLEE WRLRQRDMDE
WMRHHQLPSH LQERVRRFVQ VKWLATRGVE EESILQALPA DIRRDVQRHL CLDLVRRVPF
FSEMDDQLLD AICERLVSFL CPENTYISRE GDPVNEMLFI IRGKLESSTT NGGRSNFFNS
IILRPGDFAG EELLTWALLP KTNVHFPLST RTVRSLTEVE AFALRAEDLK FVANQFRRLH
SKKLQHTFRF YSHHWRTWAA CFIQAAWRQH QRRKLAESLS RWESYSWWSE DHPSGDKPRQ
EGTSSGGTRT IAEGAIAHMH KLASASRRFR TEDIAIRRLQ KPDEPDFSAD HFD
//
