ID C5Y3R0_SORBI Unreviewed; 834 AA.
AC C5Y3R0;
DT 01-SEP-2009, integrated into UniProtKB/TrEMBL.
DT 01-SEP-2009, sequence version 1.
DT 27-MAR-2024, entry version 82.
DE RecName: Full=Helicase ATP-binding domain-containing protein {ECO:0008006|Google:ProtNLM};
GN ORFNames=SORBI_3005G138600 {ECO:0000313|EMBL:EES08608.1};
OS Sorghum bicolor (Sorghum) (Sorghum vulgare).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; PACMAD clade;
OC Panicoideae; Andropogonodae; Andropogoneae; Sorghinae; Sorghum.
OX NCBI_TaxID=4558 {ECO:0000313|EMBL:EES08608.1, ECO:0000313|Proteomes:UP000000768};
RN [1] {ECO:0000313|EMBL:EES08608.1, ECO:0000313|Proteomes:UP000000768}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. BTx623 {ECO:0000313|Proteomes:UP000000768};
RX PubMed=19189423; DOI=10.1038/nature07723;
RA Paterson A.H., Bowers J.E., Bruggmann R., Dubchak I., Grimwood J.,
RA Gundlach H., Haberer G., Hellsten U., Mitros T., Poliakov A., Schmutz J.,
RA Spannagl M., Tang H., Wang X., Wicker T., Bharti A.K., Chapman J.,
RA Feltus F.A., Gowik U., Grigoriev I.V., Lyons E., Maher C.A., Martis M.,
RA Narechania A., Otillar R.P., Penning B.W., Salamov A.A., Wang Y., Zhang L.,
RA Carpita N.C., Freeling M., Gingle A.R., Hash C.T., Keller B., Klein P.,
RA Kresovich S., McCann M.C., Ming R., Peterson D.G., Mehboob-ur-Rahman,
RA Ware D., Westhoff P., Mayer K.F., Messing J., Rokhsar D.S.;
RT "The Sorghum bicolor genome and the diversification of grasses.";
RL Nature 457:551-556(2009).
RN [2] {ECO:0000313|Proteomes:UP000000768}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. BTx623 {ECO:0000313|Proteomes:UP000000768};
RX PubMed=29161754; DOI=10.1111/tpj.13781;
RA McCormick R.F., Truong S.K., Sreedasyam A., Jenkins J., Shu S., Sims D.,
RA Kennedy M., Amirebrahimi M., Weers B.D., McKinley B., Mattison A.,
RA Morishige D.T., Grimwood J., Schmutz J., Mullet J.E.;
RT "The Sorghum bicolor reference genome: improved assembly, gene annotations,
RT a transcriptome atlas, and signatures of genome organization.";
RL Plant J. 93:338-354(2018).
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DR EMBL; CM000764; EES08608.1; -; Genomic_DNA.
DR RefSeq; XP_002449620.1; XM_002449575.1.
DR AlphaFoldDB; C5Y3R0; -.
DR STRING; 4558.C5Y3R0; -.
DR EnsemblPlants; EES08608; EES08608; SORBI_3005G138600.
DR GeneID; 8056979; -.
DR Gramene; EES08608; EES08608; SORBI_3005G138600.
DR KEGG; sbi:8056979; -.
DR eggNOG; KOG0344; Eukaryota.
DR HOGENOM; CLU_005122_8_1_1; -.
DR InParanoid; C5Y3R0; -.
DR OMA; QVYYIYN; -.
DR OrthoDB; 34695at2759; -.
DR Proteomes; UP000000768; Chromosome 5.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0004386; F:helicase activity; IEA:UniProtKB-KW.
DR GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR GO; GO:0006281; P:DNA repair; IEA:InterPro.
DR CDD; cd17991; DEXHc_TRCF; 1.
DR Gene3D; 2.40.10.170; -; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR Gene3D; 3.90.1150.50; Transcription-repair-coupling factor, D7 domain; 1.
DR InterPro; IPR003711; CarD-like/TRCF_RID.
DR InterPro; IPR036101; CarD-like/TRCF_RID_sf.
DR InterPro; IPR011545; DEAD/DEAH_box_helicase_dom.
DR InterPro; IPR014001; Helicase_ATP-bd.
DR InterPro; IPR001650; Helicase_C.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR037235; TRCF-like_C_D7.
DR InterPro; IPR005118; TRCF_C.
DR PANTHER; PTHR14025; FANCONI ANEMIA GROUP M FANCM FAMILY MEMBER; 1.
DR PANTHER; PTHR14025:SF20; FANCONI ANEMIA GROUP M PROTEIN; 1.
DR Pfam; PF02559; CarD_TRCF_RID; 1.
DR Pfam; PF00270; DEAD; 1.
DR Pfam; PF00271; Helicase_C; 1.
DR Pfam; PF03461; TRCF; 1.
DR SMART; SM01058; CarD_TRCF; 1.
DR SMART; SM00487; DEXDc; 1.
DR SMART; SM00490; HELICc; 1.
DR SMART; SM00982; TRCF; 1.
DR SUPFAM; SSF141259; CarD-like; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF143517; TRCF domain-like; 1.
DR PROSITE; PS51192; HELICASE_ATP_BIND_1; 1.
DR PROSITE; PS51194; HELICASE_CTER; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Helicase {ECO:0000256|ARBA:ARBA00022806};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000000768}.
FT DOMAIN 296..458
FT /note="Helicase ATP-binding"
FT /evidence="ECO:0000259|PROSITE:PS51192"
FT DOMAIN 467..633
FT /note="Helicase C-terminal"
FT /evidence="ECO:0000259|PROSITE:PS51194"
FT REGION 80..106
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 125..156
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 86..105
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 125..142
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 834 AA; 92680 MW; 4146994CC0193658 CRC64;
MAAPPPHAPP AGSPQPLLLL LHHHPPALVL RVRLRPRGLR LARAPPPAAT ATSTAAAASV
APDDISQLNH RLRAIARRRE AASTLQGGGA ASSSSSSSSS PVDPSQAEAY LRMIRDQQRL
GLRQLRGEEG ESDGDEERGA RKGVAAGSSL GHRVDPRELE PGEYVVHKKV GVGKFACISA
EDGVDYVFIQ YADGMAKLAV DQAARMLYRY NLPHEKTRPR NLSKLNDPST WEKRRLKGKL
AVQKMVVNLM ELYLQRMRLG RPPYPKPASM DDFAAEFPYE PTPDQCQAFI DVEKDLTERE
TPMDRLICGD VGFGKTEVAM RAIFIVVSAG FQAMVLAPTI ILAKQHYDVM TERFANYPEI
KIAIFSGAQS KEEKDELITK IKNGDLHIIV GTHALLTERM VYSNLGLLVV DEEQKFGVQQ
KEKIASYKSS IDVLTLSATP IPRTLYLALT GFRDASLMST PPPERVAVKT YVSAFSKERA
LSAIKFELQR GGQVFYVVPR IKAIDDVLQF LKDSLPDVPI AVAHGKKMSK SIQLAMEDFA
SGEVKILVCT HIIESGIDIA NANTMIVQFA ELYGLAQLYQ LRGRVGRSGR EGFAYLFYTD
KSLLSRVATD RLGAIEEHSE LGQGFHVAEK DMGIRGFGSL FGDQQSGDVA NVGIDLFFDM
LFDSLSKVDQ FCLVPVLYKD VQLDINISPR LPSEYISYLE NPVELLNEAA KAAEKDLWAL
IQFTEDLRRR YGKEPRDMEL LLKKLYVRRM AADLGISRIY PSGKTIFMKT NMNKKVFRLM
TEAMTSETHR NSLSFAGKEI KAELLVSLPD TLLLNWLFHC LSDCYTVIPA LVKY
//
