ID C5Y7F8_SORBI Unreviewed; 1116 AA.
AC C5Y7F8;
DT 01-SEP-2009, integrated into UniProtKB/TrEMBL.
DT 01-SEP-2009, sequence version 1.
DT 27-MAR-2024, entry version 84.
DE RecName: Full=Protein kinase domain-containing protein {ECO:0000259|PROSITE:PS50011};
GN ORFNames=SORBI_3005G205300 {ECO:0000313|EMBL:EES10213.1};
OS Sorghum bicolor (Sorghum) (Sorghum vulgare).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; PACMAD clade;
OC Panicoideae; Andropogonodae; Andropogoneae; Sorghinae; Sorghum.
OX NCBI_TaxID=4558 {ECO:0000313|EMBL:EES10213.1, ECO:0000313|Proteomes:UP000000768};
RN [1] {ECO:0000313|EMBL:EES10213.1, ECO:0000313|Proteomes:UP000000768}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. BTx623 {ECO:0000313|Proteomes:UP000000768};
RX PubMed=19189423; DOI=10.1038/nature07723;
RA Paterson A.H., Bowers J.E., Bruggmann R., Dubchak I., Grimwood J.,
RA Gundlach H., Haberer G., Hellsten U., Mitros T., Poliakov A., Schmutz J.,
RA Spannagl M., Tang H., Wang X., Wicker T., Bharti A.K., Chapman J.,
RA Feltus F.A., Gowik U., Grigoriev I.V., Lyons E., Maher C.A., Martis M.,
RA Narechania A., Otillar R.P., Penning B.W., Salamov A.A., Wang Y., Zhang L.,
RA Carpita N.C., Freeling M., Gingle A.R., Hash C.T., Keller B., Klein P.,
RA Kresovich S., McCann M.C., Ming R., Peterson D.G., Mehboob-ur-Rahman,
RA Ware D., Westhoff P., Mayer K.F., Messing J., Rokhsar D.S.;
RT "The Sorghum bicolor genome and the diversification of grasses.";
RL Nature 457:551-556(2009).
RN [2] {ECO:0000313|Proteomes:UP000000768}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. BTx623 {ECO:0000313|Proteomes:UP000000768};
RX PubMed=29161754; DOI=10.1111/tpj.13781;
RA McCormick R.F., Truong S.K., Sreedasyam A., Jenkins J., Shu S., Sims D.,
RA Kennedy M., Amirebrahimi M., Weers B.D., McKinley B., Mattison A.,
RA Morishige D.T., Grimwood J., Schmutz J., Mullet J.E.;
RT "The Sorghum bicolor reference genome: improved assembly, gene annotations,
RT a transcriptome atlas, and signatures of genome organization.";
RL Plant J. 93:338-354(2018).
CC -!- SIMILARITY: Belongs to the protein kinase superfamily. Ser/Thr protein
CC kinase family. {ECO:0000256|ARBA:ARBA00008684}.
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DR EMBL; CM000764; EES10213.1; -; Genomic_DNA.
DR RefSeq; XP_002451225.1; XM_002451180.1.
DR AlphaFoldDB; C5Y7F8; -.
DR EnsemblPlants; EES10213; EES10213; SORBI_3005G205300.
DR GeneID; 8082069; -.
DR Gramene; EES10213; EES10213; SORBI_3005G205300.
DR KEGG; sbi:8082069; -.
DR eggNOG; ENOG502QPYS; Eukaryota.
DR HOGENOM; CLU_000288_22_0_1; -.
DR InParanoid; C5Y7F8; -.
DR OMA; NQCTPPL; -.
DR OrthoDB; 3681815at2759; -.
DR Proteomes; UP000000768; Chromosome 5.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR GO; GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
DR GO; GO:0016310; P:phosphorylation; IEA:UniProtKB-KW.
DR Gene3D; 3.80.10.10; Ribonuclease Inhibitor; 5.
DR Gene3D; 1.10.510.10; Transferase(Phosphotransferase) domain 1; 1.
DR InterPro; IPR011009; Kinase-like_dom_sf.
DR InterPro; IPR001611; Leu-rich_rpt.
DR InterPro; IPR003591; Leu-rich_rpt_typical-subtyp.
DR InterPro; IPR032675; LRR_dom_sf.
DR InterPro; IPR013210; LRR_N_plant-typ.
DR InterPro; IPR000719; Prot_kinase_dom.
DR InterPro; IPR017441; Protein_kinase_ATP_BS.
DR InterPro; IPR001245; Ser-Thr/Tyr_kinase_cat_dom.
DR InterPro; IPR008271; Ser/Thr_kinase_AS.
DR PANTHER; PTHR48053; LEUCINE RICH REPEAT FAMILY PROTEIN, EXPRESSED; 1.
DR PANTHER; PTHR48053:SF168; LEUCINE RICH REPEAT FAMILY PROTEIN, EXPRESSED; 1.
DR Pfam; PF00560; LRR_1; 12.
DR Pfam; PF13855; LRR_8; 2.
DR Pfam; PF08263; LRRNT_2; 1.
DR Pfam; PF07714; PK_Tyr_Ser-Thr; 1.
DR PRINTS; PR00019; LEURICHRPT.
DR SMART; SM00369; LRR_TYP; 10.
DR SMART; SM00220; S_TKc; 1.
DR SUPFAM; SSF52058; L domain-like; 1.
DR SUPFAM; SSF56112; Protein kinase-like (PK-like); 1.
DR SUPFAM; SSF52047; RNI-like; 1.
DR PROSITE; PS00107; PROTEIN_KINASE_ATP; 1.
DR PROSITE; PS50011; PROTEIN_KINASE_DOM; 1.
DR PROSITE; PS00108; PROTEIN_KINASE_ST; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000256|PROSITE-
KW ProRule:PRU10141}; Kinase {ECO:0000256|ARBA:ARBA00022777};
KW Leucine-rich repeat {ECO:0000256|ARBA:ARBA00022614};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741, ECO:0000256|PROSITE-
KW ProRule:PRU10141}; Reference proteome {ECO:0000313|Proteomes:UP000000768};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Serine/threonine-protein kinase {ECO:0000256|ARBA:ARBA00022527};
KW Signal {ECO:0000256|ARBA:ARBA00022729, ECO:0000256|SAM:SignalP};
KW Transferase {ECO:0000256|ARBA:ARBA00022679};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT SIGNAL 1..26
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 27..1116
FT /note="Protein kinase domain-containing protein"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5002960079"
FT TRANSMEM 744..769
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 801..1104
FT /note="Protein kinase"
FT /evidence="ECO:0000259|PROSITE:PS50011"
FT BINDING 830
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU10141"
SQ SEQUENCE 1116 AA; 121065 MW; A0B981559EDA018D CRC64;
MSHIAIHSNS ILPLLAFISI HFLALCQYTS PAALNESSAL LCLKSQLRDP SGALASWRDD
SPAFCQWHGV TCGSRQQASR VIALDLESEN IAGSIFPCVA NLSFLERIHM PNNQLDGQIS
PDIGQLTQLR YLNLSMNSLR GEIPEALSAC SHLETIDLDS NSLQGEIPPS LARCSSLQTV
ILGYNNLQGS IPPQLGLLPS LYTLFLPSNN LTGSIPEFLG QSKNLTWVNL QNNSLTGWIP
PALFNCTSLH YIDLSHNALS GSVPPFLQAS SSALNYLSLY ENNLSGEIPS SLGNLSSLAF
LLLSHNSLGG RVPESLGKLK TLQALDLSYN NLSGTVAPAI YNISSLNFLG LGANQIVGTL
PTSIGNTLTS ITELILEGSR FEGPIPASLA NATNLQYLDL RSNAFTGVIP SLGSLTLLSY
LDLGANRLEA GDWSFMSSLV NCTQLKNLWL DRNNLQGTIS TYITNIPKSL EIMVLKHNQF
SGSIPSEIGK FTNLTVIQLD NNFLSGEIPD TLGNLQNMSI LTISKNQFSR EIPRSIGKLE
QLTELLFNEN NLTGLIPSSL EGCKQLTTLN LSSNSLYGGI PRELFSISTL SVGLDLSNNK
LTGDIPFEIG GLINLNSLSL SNNRLSGEIP STLGQCLLLE SLHLQANNLQ GSIPDSFINL
KGITVMDLSQ NNLSGRIPDF LESLSSLQIL NLSLNDLEGP VPGGGIFAKP NDVYIQGNNK
LCATSPDLQV PQCLTSRPQR KKHAYILAVL VSLASVAAVA MACVAVIILK KRRKGKQLTS
QSLKELKNFS YGDLFKATDG FSPNSIVGSG RFGLVYKGQF KVEECAVAIK VFRLDQFGAP
SNFLSECEAL RNIRHRNLIR VISVCSTFDP TGNEFKALIL EYMVNGNLES WLHQKEYTES
TKRPLSLGTR IAIAADIAAA LDYLHNRCTP PLVHRDLKPS NVLLNDEMVA SLSDFGLAKF
LSVDFSTGFD NSSSAVGPRG SIGYIAPEYG MGCKISVGSD IYSYGIILLE IITGRRPTDD
MFKDGVNIRN FVESSLPLNI HNILEPNLTG YHEGEDGGQE MVEMQHCAMQ LANLGLKCSE
MSPKDRPKTE EVYAEMLAIK EEFSTLCSLG SVSMLL
//
