ID C5Y8G1_SORBI Unreviewed; 726 AA.
AC C5Y8G1;
DT 01-SEP-2009, integrated into UniProtKB/TrEMBL.
DT 01-SEP-2009, sequence version 1.
DT 27-MAR-2024, entry version 82.
DE RecName: Full=AAA+ ATPase domain-containing protein {ECO:0008006|Google:ProtNLM};
GN ORFNames=SORBI_3005G224000 {ECO:0000313|EMBL:EES09021.1};
OS Sorghum bicolor (Sorghum) (Sorghum vulgare).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; PACMAD clade;
OC Panicoideae; Andropogonodae; Andropogoneae; Sorghinae; Sorghum.
OX NCBI_TaxID=4558 {ECO:0000313|EMBL:EES09021.1, ECO:0000313|Proteomes:UP000000768};
RN [1] {ECO:0000313|EMBL:EES09021.1, ECO:0000313|Proteomes:UP000000768}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. BTx623 {ECO:0000313|Proteomes:UP000000768};
RX PubMed=19189423; DOI=10.1038/nature07723;
RA Paterson A.H., Bowers J.E., Bruggmann R., Dubchak I., Grimwood J.,
RA Gundlach H., Haberer G., Hellsten U., Mitros T., Poliakov A., Schmutz J.,
RA Spannagl M., Tang H., Wang X., Wicker T., Bharti A.K., Chapman J.,
RA Feltus F.A., Gowik U., Grigoriev I.V., Lyons E., Maher C.A., Martis M.,
RA Narechania A., Otillar R.P., Penning B.W., Salamov A.A., Wang Y., Zhang L.,
RA Carpita N.C., Freeling M., Gingle A.R., Hash C.T., Keller B., Klein P.,
RA Kresovich S., McCann M.C., Ming R., Peterson D.G., Mehboob-ur-Rahman,
RA Ware D., Westhoff P., Mayer K.F., Messing J., Rokhsar D.S.;
RT "The Sorghum bicolor genome and the diversification of grasses.";
RL Nature 457:551-556(2009).
RN [2] {ECO:0000313|Proteomes:UP000000768}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. BTx623 {ECO:0000313|Proteomes:UP000000768};
RX PubMed=29161754; DOI=10.1111/tpj.13781;
RA McCormick R.F., Truong S.K., Sreedasyam A., Jenkins J., Shu S., Sims D.,
RA Kennedy M., Amirebrahimi M., Weers B.D., McKinley B., Mattison A.,
RA Morishige D.T., Grimwood J., Schmutz J., Mullet J.E.;
RT "The Sorghum bicolor reference genome: improved assembly, gene annotations,
RT a transcriptome atlas, and signatures of genome organization.";
RL Plant J. 93:338-354(2018).
CC -!- SIMILARITY: Belongs to the disease resistance NB-LRR family.
CC {ECO:0000256|ARBA:ARBA00008894}.
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DR EMBL; CM000764; EES09021.1; -; Genomic_DNA.
DR RefSeq; XP_002450033.1; XM_002449988.1.
DR AlphaFoldDB; C5Y8G1; -.
DR STRING; 4558.C5Y8G1; -.
DR EnsemblPlants; EES09021; EES09021; SORBI_3005G224000.
DR GeneID; 8076343; -.
DR Gramene; EES09021; EES09021; SORBI_3005G224000.
DR KEGG; sbi:8076343; -.
DR eggNOG; KOG4658; Eukaryota.
DR HOGENOM; CLU_000837_25_0_1; -.
DR InParanoid; C5Y8G1; -.
DR OMA; RIFGHEY; -.
DR OrthoDB; 352669at2759; -.
DR Proteomes; UP000000768; Chromosome 5.
DR GO; GO:0043531; F:ADP binding; IEA:InterPro.
DR GO; GO:0006952; P:defense response; IEA:UniProtKB-KW.
DR GO; GO:0051707; P:response to other organism; IEA:UniProt.
DR CDD; cd14798; RX-CC_like; 1.
DR Gene3D; 1.20.5.4130; -; 1.
DR Gene3D; 1.10.8.430; Helical domain of apoptotic protease-activating factors; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR Gene3D; 3.80.10.10; Ribonuclease Inhibitor; 1.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR042197; Apaf_helical.
DR InterPro; IPR044974; Disease_R_plants.
DR InterPro; IPR032675; LRR_dom_sf.
DR InterPro; IPR002182; NB-ARC.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR038005; RX-like_CC.
DR InterPro; IPR041118; Rx_N.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR PANTHER; PTHR23155; DISEASE RESISTANCE PROTEIN RP; 1.
DR PANTHER; PTHR23155:SF1116; OS11G0657900 PROTEIN; 1.
DR Pfam; PF00931; NB-ARC; 1.
DR Pfam; PF18052; Rx_N; 1.
DR PRINTS; PR00364; DISEASERSIST.
DR SUPFAM; SSF52058; L domain-like; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
PE 3: Inferred from homology;
KW Coiled coil {ECO:0000256|ARBA:ARBA00023054};
KW Leucine-rich repeat {ECO:0000256|ARBA:ARBA00022614};
KW Plant defense {ECO:0000256|ARBA:ARBA00022821};
KW Reference proteome {ECO:0000313|Proteomes:UP000000768}.
FT DOMAIN 7..97
FT /note="Disease resistance N-terminal"
FT /evidence="ECO:0000259|Pfam:PF18052"
FT DOMAIN 173..413
FT /note="NB-ARC"
FT /evidence="ECO:0000259|Pfam:PF00931"
SQ SEQUENCE 726 AA; 82055 MW; CEDB2EC7CA72BABE CRC64;
MEFATGALGT LLPKLGQLLQ DEYNLQKGVK KDIQFVRKEL ESMHAALRDV GEVPQEQLKE
VIRIWARDVR ELSYDMEDIV DTFLVRVQGS EPPSKRSVKR FVKKMTSIVS NAKTRHDIGQ
EIKDIKERVK DVAERRDRYK VDAITPTKTA VDPRITALYT KAASLVGIDE PREELISMLT
KEDVGESSVG QRIVSIVGFG GLGKTTLAKA VYDKIKQQYN CTAFISVSRD PDIIKILKDL
LYELDKNEYM GIHNAALGQQ HLTDLVQEFL KNKRYLIVID DIWHTKPWEM IRCALPENCR
KSGVLTTTRI IDVAEHVGGC YRMKLLTQDS SKILFYGRIF GSIDKCPPQF SDVSEKVLKK
CGGVPLAIVT ISSLLANKSR NINEWYDVCD AVGAGVGNNP GMDDMRKILL LSYYDLTPQL
KTCILYLSIF PEDYEINKFR LIFRWIAEGF VHQGDGRQSL HEIGQSYFNE LLNRSLIQPT
DMDDDEMNPF SCQVHDMVLD LICSLSRDEC FAATLNGDCK EITSSLGSKA RRLSIYNTTW
PTINMSTLRS LTICSYALIN SMPPLSSFYL LRVLDLEDCN LSDHSSIEFV GKLLHMRYLS
LAGTGYAGDI PREIGKLLFL QSFKFDGTDI KVLPLSFFGL RQLMSLYVGH NTRLPTTSGL
RNLSSLEMLW INVDSAYVAE QLGHLTQLKV LGVVLIKDKE GRCDKSMCSL PWQTAQNPKS
RSSNPR
//
