ID C5Z279_SORBI Unreviewed; 524 AA.
AC C5Z279;
DT 01-SEP-2009, integrated into UniProtKB/TrEMBL.
DT 05-OCT-2016, sequence version 2.
DT 27-MAR-2024, entry version 57.
DE RecName: Full=Homeobox domain-containing protein {ECO:0000259|PROSITE:PS50071};
GN ORFNames=SORBI_3010G006300 {ECO:0000313|EMBL:EER89055.2};
OS Sorghum bicolor (Sorghum) (Sorghum vulgare).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; PACMAD clade;
OC Panicoideae; Andropogonodae; Andropogoneae; Sorghinae; Sorghum.
OX NCBI_TaxID=4558 {ECO:0000313|EMBL:EER89055.2, ECO:0000313|Proteomes:UP000000768};
RN [1] {ECO:0000313|EMBL:EER89055.2, ECO:0000313|Proteomes:UP000000768}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. BTx623 {ECO:0000313|Proteomes:UP000000768};
RX PubMed=19189423; DOI=10.1038/nature07723;
RA Paterson A.H., Bowers J.E., Bruggmann R., Dubchak I., Grimwood J.,
RA Gundlach H., Haberer G., Hellsten U., Mitros T., Poliakov A., Schmutz J.,
RA Spannagl M., Tang H., Wang X., Wicker T., Bharti A.K., Chapman J.,
RA Feltus F.A., Gowik U., Grigoriev I.V., Lyons E., Maher C.A., Martis M.,
RA Narechania A., Otillar R.P., Penning B.W., Salamov A.A., Wang Y., Zhang L.,
RA Carpita N.C., Freeling M., Gingle A.R., Hash C.T., Keller B., Klein P.,
RA Kresovich S., McCann M.C., Ming R., Peterson D.G., Mehboob-ur-Rahman,
RA Ware D., Westhoff P., Mayer K.F., Messing J., Rokhsar D.S.;
RT "The Sorghum bicolor genome and the diversification of grasses.";
RL Nature 457:551-556(2009).
RN [2] {ECO:0000313|Proteomes:UP000000768}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. BTx623 {ECO:0000313|Proteomes:UP000000768};
RX PubMed=29161754; DOI=10.1111/tpj.13781;
RA McCormick R.F., Truong S.K., Sreedasyam A., Jenkins J., Shu S., Sims D.,
RA Kennedy M., Amirebrahimi M., Weers B.D., McKinley B., Mattison A.,
RA Morishige D.T., Grimwood J., Schmutz J., Mullet J.E.;
RT "The Sorghum bicolor reference genome: improved assembly, gene annotations,
RT a transcriptome atlas, and signatures of genome organization.";
RL Plant J. 93:338-354(2018).
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123,
CC ECO:0000256|PROSITE-ProRule:PRU00108}.
CC -!- SIMILARITY: Belongs to the TALE/BELL homeobox family.
CC {ECO:0000256|ARBA:ARBA00006454}.
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DR EMBL; CM000769; EER89055.2; -; Genomic_DNA.
DR AlphaFoldDB; C5Z279; -.
DR EnsemblPlants; EER89055; EER89055; SORBI_3010G006300.
DR Gramene; EER89055; EER89055; SORBI_3010G006300.
DR eggNOG; KOG0773; Eukaryota.
DR HOGENOM; CLU_3074976_0_0_1; -.
DR InParanoid; C5Z279; -.
DR OMA; HAEFITG; -.
DR OrthoDB; 3180467at2759; -.
DR Proteomes; UP000000768; Chromosome 10.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0000981; F:DNA-binding transcription factor activity, RNA polymerase II-specific; IBA:GO_Central.
DR GO; GO:0000978; F:RNA polymerase II cis-regulatory region sequence-specific DNA binding; IBA:GO_Central.
DR GO; GO:0006357; P:regulation of transcription by RNA polymerase II; IBA:GO_Central.
DR CDD; cd00086; homeodomain; 1.
DR Gene3D; 1.10.10.60; Homeodomain-like; 1.
DR InterPro; IPR009057; Homeobox-like_sf.
DR InterPro; IPR001356; Homeobox_dom.
DR InterPro; IPR008422; Homeobox_KN_domain.
DR InterPro; IPR006563; POX_dom.
DR PANTHER; PTHR11850; HOMEOBOX PROTEIN TRANSCRIPTION FACTORS; 1.
DR PANTHER; PTHR11850:SF377; OS06G0108900 PROTEIN; 1.
DR Pfam; PF05920; Homeobox_KN; 1.
DR Pfam; PF07526; POX; 1.
DR SMART; SM00389; HOX; 1.
DR SMART; SM00574; POX; 1.
DR SUPFAM; SSF46689; Homeodomain-like; 1.
DR PROSITE; PS50071; HOMEOBOX_2; 1.
PE 3: Inferred from homology;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW DNA-binding {ECO:0000256|PROSITE-ProRule:PRU00108};
KW Homeobox {ECO:0000256|ARBA:ARBA00023155, ECO:0000256|PROSITE-
KW ProRule:PRU00108};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242, ECO:0000256|PROSITE-
KW ProRule:PRU00108}; Reference proteome {ECO:0000313|Proteomes:UP000000768}.
FT DOMAIN 316..379
FT /note="Homeobox"
FT /evidence="ECO:0000259|PROSITE:PS50071"
FT DNA_BIND 318..380
FT /note="Homeobox"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00108"
FT COILED 192..226
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 524 AA; 57040 MW; 96E3A934803C3498 CRC64;
MAVHHPHLLD FSPPPNTVAM EAPPAPHFDH GGHHHHHLLG LHVDGGVGMS VGGGVPHRAL
ADDDTVAAWA PQAAVSLSLY NYDNTAGGSS SSLFGHDEPQ FGAMPPAAAL ALPNHQQLPT
TTSSMQQPFQ LRSSKYLAPV QDLLSEFCSL EGDLLHAMNK RAPRAGNKWD DVETSSSSSG
LWGHPSLSSM DLLELERRKA RLLSMVEEVD RRYRRYREQM RAVEVSFEAV AGAGASQVYT
RLALRAMSRH FRCLRDALVA QVRALRKAMG ERDGGPGAAA AATAAGATKG DTPRLKVLDQ
CLRQQRAFQH PGTIENYPWR PQRGLPERAV AVLRAWLFEH FLHPYPNDVD KHILARQTGL
SRSQVSNWFI NARVRLWKPM IEEMYTEEVN QKSNATPQNP SGGGVIKPEQ MSTTAVPAAI
GGDHSHFLAT SAGNPSSSMI SSSILMTAAD CGGSGGGDHL FSSYPSMHRS HGGAVSLTLG
LQQQPFVSTM MHHQRPLMLH GDEQEPVLPY RDLMGSQLLH DFAG
//
