ID C6A0B0_THESM Unreviewed; 352 AA.
AC C6A0B0;
DT 01-SEP-2009, integrated into UniProtKB/TrEMBL.
DT 01-SEP-2009, sequence version 1.
DT 27-MAR-2024, entry version 66.
DE SubName: Full=Glucose-1-phosphate thymidylyltransferase {ECO:0000313|EMBL:ACS91091.1};
DE EC=2.7.7.24 {ECO:0000313|EMBL:ACS91091.1};
GN OrderedLocusNames=TSIB_2044 {ECO:0000313|EMBL:ACS91091.1};
OS Thermococcus sibiricus (strain DSM 12597 / MM 739).
OC Archaea; Euryarchaeota; Thermococci; Thermococcales; Thermococcaceae;
OC Thermococcus.
OX NCBI_TaxID=604354 {ECO:0000313|EMBL:ACS91091.1, ECO:0000313|Proteomes:UP000009079};
RN [1] {ECO:0000313|EMBL:ACS91091.1, ECO:0000313|Proteomes:UP000009079}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 12597 / MM 739 {ECO:0000313|Proteomes:UP000009079};
RX PubMed=19447963; DOI=10.1128/AEM.00718-09;
RA Mardanov A.V., Ravin N.V., Svetlitchnyi V.A., Beletsky A.V.,
RA Miroshnichenko M.L., Bonch-Osmolovskaya E.A., Skryabin K.G.;
RT "Metabolic versatility and indigenous origin of the archaeon Thermococcus
RT sibiricus, isolated from a siberian oil reservoir, as revealed by genome
RT analysis.";
RL Appl. Environ. Microbiol. 75:4580-4588(2009).
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DR EMBL; CP001463; ACS91091.1; -; Genomic_DNA.
DR RefSeq; WP_015850307.1; NC_012883.1.
DR AlphaFoldDB; C6A0B0; -.
DR STRING; 604354.TSIB_2044; -.
DR GeneID; 8097058; -.
DR KEGG; tsi:TSIB_2044; -.
DR eggNOG; arCOG00667; Archaea.
DR HOGENOM; CLU_029499_0_1_2; -.
DR OrthoDB; 15372at2157; -.
DR Proteomes; UP000009079; Chromosome.
DR GO; GO:0008879; F:glucose-1-phosphate thymidylyltransferase activity; IEA:UniProtKB-EC.
DR GO; GO:0009058; P:biosynthetic process; IEA:InterPro.
DR CDD; cd04189; G1P_TT_long; 1.
DR Gene3D; 2.160.10.10; Hexapeptide repeat proteins; 1.
DR InterPro; IPR005908; G1P_thy_trans_l.
DR InterPro; IPR005835; NTP_transferase_dom.
DR InterPro; IPR029044; Nucleotide-diphossugar_trans.
DR NCBIfam; TIGR01208; rmlA_long; 1.
DR PANTHER; PTHR42883; GLUCOSE-1-PHOSPHATE THYMIDYLTRANSFERASE; 1.
DR PANTHER; PTHR42883:SF2; ZGC:136439; 1.
DR Pfam; PF00483; NTP_transferase; 1.
DR SUPFAM; SSF53448; Nucleotide-diphospho-sugar transferases; 1.
PE 4: Predicted;
KW Nucleotidyltransferase {ECO:0000313|EMBL:ACS91091.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000009079};
KW Transferase {ECO:0000313|EMBL:ACS91091.1}.
FT DOMAIN 2..235
FT /note="Nucleotidyl transferase"
FT /evidence="ECO:0000259|Pfam:PF00483"
SQ SEQUENCE 352 AA; 39358 MW; 0531530AD5456735 CRC64;
MKALILSGGH GTRLRPLTYS QQKQLIPVAN KPVLFYAIED VIEAGIHDIG IIVGPSKEQV
IETVKSVDWD AEIEFIYQGE PKGLAHAIKV ASDYLGDDDF VMYLGDNILR EGIVRHLEHF
KEENFDASIL LQEVPNPQQF GVAELSEDGR TIKRLIEKPK VPPSNLALVG VYFFKPIVHE
AVRNIKPSWR DELEITDAIQ WLIDHGYRVG WTKVTGWWKD TGKPEDILEA NRLILDDIKT
SIKVKTKARI HGRVVIEEGA QIDESTVIKG PVVIGRNVVI KNSYIGPYTS IGNNCVIENT
EVEDSIILPD SEIRDAGRIV ESLIGRGVKI VRGNSHPLGR KFVIGDNSRI IL
//
