ID C6A501_THESM Unreviewed; 78 AA.
AC C6A501;
DT 01-SEP-2009, integrated into UniProtKB/TrEMBL.
DT 01-SEP-2009, sequence version 1.
DT 27-MAR-2024, entry version 55.
DE SubName: Full=2-oxoglutarate dehydrogenase, E2 component, dihydrolipoamide succinyltransferase {ECO:0000313|EMBL:ACS90696.1};
DE EC=2.3.1.61 {ECO:0000313|EMBL:ACS90696.1};
GN OrderedLocusNames=TSIB_1645 {ECO:0000313|EMBL:ACS90696.1};
OS Thermococcus sibiricus (strain DSM 12597 / MM 739).
OC Archaea; Euryarchaeota; Thermococci; Thermococcales; Thermococcaceae;
OC Thermococcus.
OX NCBI_TaxID=604354 {ECO:0000313|EMBL:ACS90696.1, ECO:0000313|Proteomes:UP000009079};
RN [1] {ECO:0000313|EMBL:ACS90696.1, ECO:0000313|Proteomes:UP000009079}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 12597 / MM 739 {ECO:0000313|Proteomes:UP000009079};
RX PubMed=19447963; DOI=10.1128/AEM.00718-09;
RA Mardanov A.V., Ravin N.V., Svetlitchnyi V.A., Beletsky A.V.,
RA Miroshnichenko M.L., Bonch-Osmolovskaya E.A., Skryabin K.G.;
RT "Metabolic versatility and indigenous origin of the archaeon Thermococcus
RT sibiricus, isolated from a siberian oil reservoir, as revealed by genome
RT analysis.";
RL Appl. Environ. Microbiol. 75:4580-4588(2009).
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DR EMBL; CP001463; ACS90696.1; -; Genomic_DNA.
DR RefSeq; WP_015849912.1; NC_012883.1.
DR AlphaFoldDB; C6A501; -.
DR STRING; 604354.TSIB_1645; -.
DR GeneID; 8096655; -.
DR KEGG; tsi:TSIB_1645; -.
DR eggNOG; arCOG01706; Archaea.
DR HOGENOM; CLU_016733_7_7_2; -.
DR OrthoDB; 99914at2157; -.
DR Proteomes; UP000009079; Chromosome.
DR GO; GO:0004149; F:dihydrolipoyllysine-residue succinyltransferase activity; IEA:UniProtKB-EC.
DR CDD; cd06849; lipoyl_domain; 1.
DR Gene3D; 2.40.50.100; -; 1.
DR InterPro; IPR003016; 2-oxoA_DH_lipoyl-BS.
DR InterPro; IPR000089; Biotin_lipoyl.
DR InterPro; IPR011053; Single_hybrid_motif.
DR Pfam; PF00364; Biotin_lipoyl; 1.
DR SUPFAM; SSF51230; Single hybrid motif; 1.
DR PROSITE; PS50968; BIOTINYL_LIPOYL; 1.
DR PROSITE; PS00189; LIPOYL; 1.
PE 4: Predicted;
KW Acyltransferase {ECO:0000313|EMBL:ACS90696.1};
KW Lipoyl {ECO:0000256|ARBA:ARBA00022823};
KW Reference proteome {ECO:0000313|Proteomes:UP000009079};
KW Transferase {ECO:0000313|EMBL:ACS90696.1}.
FT DOMAIN 2..76
FT /note="Lipoyl-binding"
FT /evidence="ECO:0000259|PROSITE:PS50968"
SQ SEQUENCE 78 AA; 8509 MW; E02F6E36D599BF5C CRC64;
MEIEVKVPTI SQEDKKGVVN QWYKKDGDVV KEGEEIAEVM IEKVTVIIKA QASGKLKILV
PENGEVSQGD VIAVVETA
//
