ID C6ARQ2_RHILS Unreviewed; 403 AA.
AC C6ARQ2;
DT 01-SEP-2009, integrated into UniProtKB/TrEMBL.
DT 01-SEP-2009, sequence version 1.
DT 27-MAR-2024, entry version 75.
DE SubName: Full=Efflux transporter, RND family, MFP subunit {ECO:0000313|EMBL:ACS57077.1};
DE Flags: Precursor;
GN OrderedLocusNames=Rleg_2816 {ECO:0000313|EMBL:ACS57077.1};
OS Rhizobium leguminosarum bv. trifolii (strain WSM1325).
OC Bacteria; Pseudomonadota; Alphaproteobacteria; Hyphomicrobiales;
OC Rhizobiaceae; Rhizobium/Agrobacterium group; Rhizobium.
OX NCBI_TaxID=395491 {ECO:0000313|EMBL:ACS57077.1, ECO:0000313|Proteomes:UP000002256};
RN [1] {ECO:0000313|EMBL:ACS57077.1, ECO:0000313|Proteomes:UP000002256}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=WSM1325 {ECO:0000313|EMBL:ACS57077.1,
RC ECO:0000313|Proteomes:UP000002256};
RX PubMed=21304718;
RA Reeve W., O'Hara G., Chain P., Ardley J., Brau L., Nandesena K., Tiwari R.,
RA Copeland A., Nolan M., Han C., Brettin T., Land M., Ovchinikova G.,
RA Ivanova N., Mavromatis K., Markowitz V., Kyrpides N., Melino V., Denton M.,
RA Yates R., Howieson J.;
RT "Complete genome sequence of Rhizobium leguminosarum bv. trifolii strain
RT WSM1325, an effective microsymbiont of annual Mediterranean clovers.";
RL Stand. Genomic Sci. 2:347-356(2010).
CC -!- SIMILARITY: Belongs to the membrane fusion protein (MFP) (TC 8.A.1)
CC family. {ECO:0000256|ARBA:ARBA00009477}.
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DR EMBL; CP001622; ACS57077.1; -; Genomic_DNA.
DR RefSeq; WP_012758251.1; NC_012850.1.
DR AlphaFoldDB; C6ARQ2; -.
DR KEGG; rlg:Rleg_2816; -.
DR HOGENOM; CLU_018816_1_2_5; -.
DR OrthoDB; 9806939at2; -.
DR Proteomes; UP000002256; Chromosome.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0022857; F:transmembrane transporter activity; IEA:InterPro.
DR Gene3D; 2.40.30.170; -; 1.
DR Gene3D; 2.40.420.20; -; 1.
DR Gene3D; 2.40.50.100; -; 1.
DR Gene3D; 1.10.287.470; Helix hairpin bin; 1.
DR InterPro; IPR032317; HlyD_D23.
DR InterPro; IPR006143; RND_pump_MFP.
DR NCBIfam; TIGR01730; RND_mfp; 1.
DR PANTHER; PTHR30469:SF13; HAE1 FAMILY EFFLUX PUMP MFP COMPONENT; 1.
DR PANTHER; PTHR30469; MULTIDRUG RESISTANCE PROTEIN MDTA; 1.
DR Pfam; PF16576; HlyD_D23; 1.
DR SUPFAM; SSF111369; HlyD-like secretion proteins; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 7..24
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 111..309
FT /note="RND efflux pump membrane fusion protein barrel-
FT sandwich"
FT /evidence="ECO:0000259|Pfam:PF16576"
FT REGION 49..81
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 65..81
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 403 AA; 43040 MW; B5A43BDE47F22411 CRC64;
MAFWKQFILS LIVIIAGFAA WVFFVPGAGD TMRDAGIPDS IVSKIAPKAE ETVDADAPAR
AQGQQRGDGQ GQGQNRRNGG GRNSAILVAT QAVVQGIVND RLNAIGTGDA IRSVAVTPQA
SGTIREILIK SGDRVKAGQV LAKLDSEEQV IARGQADVAV KAAVEKSNLY HNIKSSVSRM
DVFDSEIAEQ GARLQLQAAE LNLARRNITA PIDGIVGIVP VNIGDNVTTS IPIVTLDDRS
EILVDYWVPE RFANTVSVGQ PVEAMSVARP GKVFSGVVEA VDNRIDAASR TLRLRAKIDN
SSDELRAGMS FSVSMKFAGD KYPAVDPVSV QWDSQGSFVW QVNDYKSHKV RVSIVQRNPD
FVLVKADIKD GDVIVTQGLQ RVREGGAVRV SADVAAAAEV ATQ
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