ID C6E1V3_GEOSM Unreviewed; 636 AA.
AC C6E1V3;
DT 01-SEP-2009, integrated into UniProtKB/TrEMBL.
DT 01-SEP-2009, sequence version 1.
DT 27-MAR-2024, entry version 88.
DE SubName: Full=NADH dehydrogenase (Quinone) {ECO:0000313|EMBL:ACT18837.1};
DE EC=1.6.99.5 {ECO:0000313|EMBL:ACT18837.1};
GN OrderedLocusNames=GM21_2804 {ECO:0000313|EMBL:ACT18837.1};
OS Geobacter sp. (strain M21).
OC Bacteria; Thermodesulfobacteriota; Desulfuromonadia; Geobacterales;
OC Geobacteraceae; Geobacter.
OX NCBI_TaxID=443144 {ECO:0000313|EMBL:ACT18837.1};
RN [1] {ECO:0000313|EMBL:ACT18837.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=M21 {ECO:0000313|EMBL:ACT18837.1};
RG US DOE Joint Genome Institute;
RA Lucas S., Copeland A., Lapidus A., Glavina del Rio T., Dalin E., Tice H.,
RA Bruce D., Goodwin L., Pitluck S., Saunders E., Brettin T., Detter J.C.,
RA Han C., Larimer F., Land M., Hauser L., Kyrpides N., Ovchinnikova G.,
RA Lovley D.;
RT "Complete sequence of Geobacter sp. M21.";
RL Submitted (JUL-2009) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the complex I 51 kDa subunit family.
CC {ECO:0000256|ARBA:ARBA00007523}.
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DR EMBL; CP001661; ACT18837.1; -; Genomic_DNA.
DR AlphaFoldDB; C6E1V3; -.
DR STRING; 443144.GM21_2804; -.
DR KEGG; gem:GM21_2804; -.
DR eggNOG; COG1894; Bacteria.
DR HOGENOM; CLU_014881_3_2_7; -.
DR OrthoDB; 9805533at2; -.
DR GO; GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW.
DR GO; GO:0010181; F:FMN binding; IEA:InterPro.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0008137; F:NADH dehydrogenase (ubiquinone) activity; IEA:InterPro.
DR CDD; cd02980; TRX_Fd_family; 1.
DR Gene3D; 3.10.20.600; -; 1.
DR Gene3D; 3.30.70.20; -; 1.
DR Gene3D; 6.10.250.1450; -; 1.
DR Gene3D; 3.40.30.10; Glutaredoxin; 1.
DR Gene3D; 3.40.50.11540; NADH-ubiquinone oxidoreductase 51kDa subunit; 1.
DR Gene3D; 1.20.1440.230; NADH-ubiquinone oxidoreductase 51kDa subunit, iron-sulphur binding domain; 1.
DR InterPro; IPR017896; 4Fe4S_Fe-S-bd.
DR InterPro; IPR017900; 4Fe4S_Fe_S_CS.
DR InterPro; IPR001949; NADH-UbQ_OxRdtase_51kDa_CS.
DR InterPro; IPR011538; Nuo51_FMN-bd.
DR InterPro; IPR037225; Nuo51_FMN-bd_sf.
DR InterPro; IPR019575; Nuop51_4Fe4S-bd.
DR InterPro; IPR037207; Nuop51_4Fe4S-bd_sf.
DR InterPro; IPR019554; Soluble_ligand-bd.
DR InterPro; IPR036249; Thioredoxin-like_sf.
DR PANTHER; PTHR43578; NADH-QUINONE OXIDOREDUCTASE SUBUNIT F; 1.
DR PANTHER; PTHR43578:SF3; NADH-QUINONE OXIDOREDUCTASE SUBUNIT F; 1.
DR Pfam; PF01257; 2Fe-2S_thioredx; 1.
DR Pfam; PF01512; Complex1_51K; 1.
DR Pfam; PF14697; Fer4_21; 1.
DR Pfam; PF10589; NADH_4Fe-4S; 1.
DR Pfam; PF10531; SLBB; 1.
DR SMART; SM00928; NADH_4Fe-4S; 1.
DR SUPFAM; SSF54862; 4Fe-4S ferredoxins; 1.
DR SUPFAM; SSF142019; Nqo1 FMN-binding domain-like; 1.
DR SUPFAM; SSF142984; Nqo1 middle domain-like; 1.
DR SUPFAM; SSF140490; Nqo1C-terminal domain-like; 1.
DR SUPFAM; SSF52833; Thioredoxin-like; 1.
DR PROSITE; PS00198; 4FE4S_FER_1; 1.
DR PROSITE; PS51379; 4FE4S_FER_2; 2.
DR PROSITE; PS00645; COMPLEX1_51K_2; 1.
PE 3: Inferred from homology;
KW 4Fe-4S {ECO:0000256|ARBA:ARBA00022485};
KW Flavoprotein {ECO:0000256|ARBA:ARBA00022630};
KW FMN {ECO:0000256|ARBA:ARBA00022643}; Iron {ECO:0000256|ARBA:ARBA00023004};
KW Iron-sulfur {ECO:0000256|ARBA:ARBA00023014};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW NAD {ECO:0000256|ARBA:ARBA00023027};
KW Oxidoreductase {ECO:0000313|EMBL:ACT18837.1};
KW Translocase {ECO:0000256|ARBA:ARBA00022967}.
FT DOMAIN 560..589
FT /note="4Fe-4S ferredoxin-type"
FT /evidence="ECO:0000259|PROSITE:PS51379"
FT DOMAIN 590..621
FT /note="4Fe-4S ferredoxin-type"
FT /evidence="ECO:0000259|PROSITE:PS51379"
SQ SEQUENCE 636 AA; 68614 MW; CA8D59A9A2CABC07 CRC64;
MPRINSPAEL EAFRKGILAK RDDKKPCITL CSGSACHATG SEKVADAILA ELESHGLKDQ
VDIRRTGCHG FCEQGPIVVV YPEGISYLKV KPEDVCEIVS HTFKEKKLVE RLIYVDPNTG
EKSSHEHDIP FYKNQQRLIL GLNTKIDPKS LEDYLAVGGY QAMAKALLKM TPEQVIGEVK
QAKLRGRGGA GFPSGTKWEF ARNAPGDQKY VVVNCDEGDP GAYMDRSLME GNPFTVLEGL
LIGAYAIGAS EGYIYVRQEY PLAVDNLTVA IKKAEEHGFL GKNILGSGFD FTVKVHRGAG
AFICGEETSL LQSLEGKPGE PKPRPPFPAI KGLWGKPTNI NNVETWANIP VIINQGAEYF
SSIGTESSKG TKIFSLVGKV NNTGLVEVPM GMPLRDIIFK IGGGVPNGKK FKAVQTGGPS
GGCIPEEYLD VKVDFDELMK MGAMMGSGGM IVMDEDTCLV DIARYFLEFL SDESCGKCVP
CREGIRQMLK VMTAITQGKG KEGDIELLEN MAMATQGAAL CALGKTAPNP VLSTLKYFRH
EYEAHIKEKR CPALSCKELI AFHIDPAKCK GCGSCLRKCP ATAIEGGKKT IHVIDQEKCT
KCGTCIEACP AAFGAIAKLS GVPVPEPPAP SARALA
//
