ID   C6H3Y5_AJECH            Unreviewed;       486 AA.
AC   C6H3Y5;
DT   01-SEP-2009, integrated into UniProtKB/TrEMBL.
DT   01-SEP-2009, sequence version 1.
DT   24-JAN-2024, entry version 49.
DE   RecName: Full=Septin-type G domain-containing protein {ECO:0000259|PROSITE:PS51719};
GN   ORFNames=HCDG_01306 {ECO:0000313|EMBL:EER45727.1};
OS   Ajellomyces capsulatus (strain H143) (Darling's disease fungus)
OS   (Histoplasma capsulatum).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC   Eurotiomycetidae; Onygenales; Ajellomycetaceae; Histoplasma.
OX   NCBI_TaxID=544712 {ECO:0000313|EMBL:EER45727.1, ECO:0000313|Proteomes:UP000002624};
RN   [1] {ECO:0000313|Proteomes:UP000002624}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=H143 {ECO:0000313|Proteomes:UP000002624};
RA   Champion M., Cuomo C.A., Ma L.-J., Henn M.R., Sil A., Goldman B.,
RA   Young S.K., Kodira C.D., Zeng Q., Koehrsen M., Alvarado L., Berlin A.M.,
RA   Borenstein D., Chen Z., Engels R., Freedman E., Gellesch M., Goldberg J.,
RA   Griggs A., Gujja S., Heiman D.I., Hepburn T.A., Howarth C., Jen D.,
RA   Larson L., Lewis B., Mehta T., Park D., Pearson M., Roberts A., Saif S.,
RA   Shea T.D., Shenoy N., Sisk P., Stolte C., Sykes S., Walk T., White J.,
RA   Yandava C., Klein B., McEwen J.G., Puccia R., Goldman G.H., Felipe M.S.,
RA   Nino-Vega G., San-Blas G., Taylor J.W., Mendoza L., Galagan J.E.,
RA   Nusbaum C., Birren B.W.;
RT   "The genome sequence of Ajellomyces capsulatus strain H143.";
RL   Submitted (MAY-2009) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like
CC       GTPase superfamily. Septin GTPase family.
CC       {ECO:0000256|RuleBase:RU004560}.
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DR   EMBL; GG692419; EER45727.1; -; Genomic_DNA.
DR   AlphaFoldDB; C6H3Y5; -.
DR   STRING; 544712.C6H3Y5; -.
DR   VEuPathDB; FungiDB:HCDG_01306; -.
DR   eggNOG; KOG2655; Eukaryota.
DR   HOGENOM; CLU_021805_1_0_1; -.
DR   Proteomes; UP000002624; Unassembled WGS sequence.
DR   GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR   Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR   InterPro; IPR030379; G_SEPTIN_dom.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   PANTHER; PTHR18884; SEPTIN; 1.
DR   PANTHER; PTHR18884:SF70; SEPTIN; 1.
DR   Pfam; PF00735; Septin; 2.
DR   SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR   PROSITE; PS51719; G_SEPTIN; 1.
PE   3: Inferred from homology;
KW   GTP-binding {ECO:0000256|RuleBase:RU004560};
KW   Nucleotide-binding {ECO:0000256|RuleBase:RU004560};
KW   Reference proteome {ECO:0000313|Proteomes:UP000002624}.
FT   DOMAIN          198..486
FT                   /note="Septin-type G"
FT                   /evidence="ECO:0000259|PROSITE:PS51719"
FT   REGION          1..89
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          413..486
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        1..22
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        31..61
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        74..89
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        427..441
FT                   /note="Acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        466..486
FT                   /note="Pro residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   486 AA;  53619 MW;  3B407676F0806800 CRC64;
     MFSRYALHWQ GQNKSNMSSP APPTPGRSSP PDALPTATEN GSANANSQTV RRTSLGFLRR
     SKSTEPLSGD RKASGGRMSK RMQKEMAKEE LLRRQREAGA VAKYAPRLPD LPAPPQLKTF
     GGENARQMNT TAIPNRGGSY IDPNTPASPY SGATGGRGSE VIDPYARTES MTHRGRYSYA
     SSAVSTINSP RRVRRRKDPT PYNILVIGAR KSGKTSFLNF LRTSLQLPPK KRPTRAPDEF
     EEPVQMSAAN NNFTSHYLET EIDGERVGLT LWDSQGLESN VVDLQLRGIT SFLESKFEET
     FNEEMKVIRA PGVRDTHIHC AFLILDPARL DANIAAAQES VDDPEKSSSV RLIGGLDENL
     DIQVIRTMQG MTTVVPIISK ADTITTGHMA FLKKTVWESL KKAGLDPLEV LTLEDQDDTS
     SSDGFDRFDE QDEDDLNQQE DDDAQIQTQT ETDAEAKRPT TGRPLPRLRH GPPVPPQPSV
     AHIPPE
//