ID   C6HHD0_AJECH            Unreviewed;       838 AA.
AC   C6HHD0;
DT   01-SEP-2009, integrated into UniProtKB/TrEMBL.
DT   01-SEP-2009, sequence version 1.
DT   27-MAR-2024, entry version 47.
DE   RecName: Full=Betaine lipid synthase {ECO:0008006|Google:ProtNLM};
GN   ORFNames=HCDG_05611 {ECO:0000313|EMBL:EER40214.1};
OS   Ajellomyces capsulatus (strain H143) (Darling's disease fungus)
OS   (Histoplasma capsulatum).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC   Eurotiomycetidae; Onygenales; Ajellomycetaceae; Histoplasma.
OX   NCBI_TaxID=544712 {ECO:0000313|EMBL:EER40214.1, ECO:0000313|Proteomes:UP000002624};
RN   [1] {ECO:0000313|Proteomes:UP000002624}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=H143 {ECO:0000313|Proteomes:UP000002624};
RA   Champion M., Cuomo C.A., Ma L.-J., Henn M.R., Sil A., Goldman B.,
RA   Young S.K., Kodira C.D., Zeng Q., Koehrsen M., Alvarado L., Berlin A.M.,
RA   Borenstein D., Chen Z., Engels R., Freedman E., Gellesch M., Goldberg J.,
RA   Griggs A., Gujja S., Heiman D.I., Hepburn T.A., Howarth C., Jen D.,
RA   Larson L., Lewis B., Mehta T., Park D., Pearson M., Roberts A., Saif S.,
RA   Shea T.D., Shenoy N., Sisk P., Stolte C., Sykes S., Walk T., White J.,
RA   Yandava C., Klein B., McEwen J.G., Puccia R., Goldman G.H., Felipe M.S.,
RA   Nino-Vega G., San-Blas G., Taylor J.W., Mendoza L., Galagan J.E.,
RA   Nusbaum C., Birren B.W.;
RT   "The genome sequence of Ajellomyces capsulatus strain H143.";
RL   Submitted (MAY-2009) to the EMBL/GenBank/DDBJ databases.
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DR   EMBL; GG692427; EER40214.1; -; Genomic_DNA.
DR   AlphaFoldDB; C6HHD0; -.
DR   STRING; 544712.C6HHD0; -.
DR   VEuPathDB; FungiDB:HCDG_05611; -.
DR   eggNOG; ENOG502QQCH; Eukaryota.
DR   HOGENOM; CLU_020809_0_0_1; -.
DR   OMA; GVCDFYV; -.
DR   Proteomes; UP000002624; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   CDD; cd02440; AdoMet_MTases; 1.
DR   Gene3D; 3.40.50.150; Vaccinia Virus protein VP39; 1.
DR   InterPro; IPR021829; DUF3419.
DR   InterPro; IPR029063; SAM-dependent_MTases_sf.
DR   PANTHER; PTHR47473; BTA1P; 1.
DR   PANTHER; PTHR47473:SF1; METHYLTRANSFERASE DOMAIN-CONTAINING PROTEIN; 1.
DR   Pfam; PF11899; DUF3419; 1.
DR   Pfam; PF13489; Methyltransf_23; 1.
DR   SUPFAM; SSF53335; S-adenosyl-L-methionine-dependent methyltransferases; 1.
PE   4: Predicted;
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000002624};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        20..41
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
SQ   SEQUENCE   838 AA;  95292 MW;  3BBA43CE5F6BF512 CRC64;
     MSTMMPFLGS GRNGWSLPHL QIAAAAVFVV ALVSSVLLFV LRKPKMKHDS AIYTYFKFFY
     ASFVKPHESH GQGDQQRALE SFYKTQAAVY DATRKRLLRG REDMLGLLAA QLKYKQQSGR
     KQSPRPIWVD IGGGTGYNIE AMAAFLPVES FFAHVYLVDL SPSLSEIARQ RFSRLGWKNV
     SVVCQDARDF RLPSRTSDEL VSSDNKVNKL RPATGRADLV TMSYSLSMIP DYYSVVDSCT
     SLLSPSGTIG VCDFYVQSIV DLASRNYTGG VFNRHVNWVG RAFWRAWFDA DRVALDGARR
     DYLEYRFGTV ISASARNYLL GGIPYYIFIG CQKEIYGNQP NPSSKEIVEK LDAAYTESPY
     LAPANHRKDV SMALEKQVAE IRSKAYESAV INLTTNLPLP SSFYQNHHWR IYYNDMLTKH
     TQFGNEYIYA FTWEDPRVDN RLLNIGSDDV ILAITSAGDN ILDYLQYNPR RVHAVDLNPT
     QNHLLELKVA SFTALGYRDF WKIFGEGKHP NFRELLISHL SPHLSSHAFQ YWLDHSNSIS
     PRSGVGLYET GGSRYAIKMV RYLFTIFGLS AEVKRLCEAQ TLDEQRKIWP RIRRVLMSRL
     LHWAVVGTEW FAWKAAGVPA AQRNMIITDF LNRSGLAGGV KKDTEVSGQA IWEYVVNTLD
     PVVKDTLISN DNYFYYLCLQ GRYSRRCHPS YLTPKAHMKL STPHAFDGLR IHTDEINEVI
     ARIAPGTLTI AVVMDSMDWF NPAKEDASKQ ARALNSSLKM GGRILLRSAS IQPWYIKNFE
     ENGFTARRVG ARFPGSCIDR KYVRLNVDMQ KDQRHRSSPS CHMCHLSLDA GEDEFRLK
//