ID   C6HNK1_AJECH            Unreviewed;       402 AA.
AC   C6HNK1;
DT   01-SEP-2009, integrated into UniProtKB/TrEMBL.
DT   01-SEP-2009, sequence version 1.
DT   27-MAR-2024, entry version 43.
DE   RecName: Full=phosphatidylserine decarboxylase {ECO:0000256|ARBA:ARBA00012243};
DE            EC=4.1.1.65 {ECO:0000256|ARBA:ARBA00012243};
GN   ORFNames=HCDG_07782 {ECO:0000313|EMBL:EER38047.1};
OS   Ajellomyces capsulatus (strain H143) (Darling's disease fungus)
OS   (Histoplasma capsulatum).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC   Eurotiomycetidae; Onygenales; Ajellomycetaceae; Histoplasma.
OX   NCBI_TaxID=544712 {ECO:0000313|EMBL:EER38047.1, ECO:0000313|Proteomes:UP000002624};
RN   [1] {ECO:0000313|Proteomes:UP000002624}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=H143 {ECO:0000313|Proteomes:UP000002624};
RA   Champion M., Cuomo C.A., Ma L.-J., Henn M.R., Sil A., Goldman B.,
RA   Young S.K., Kodira C.D., Zeng Q., Koehrsen M., Alvarado L., Berlin A.M.,
RA   Borenstein D., Chen Z., Engels R., Freedman E., Gellesch M., Goldberg J.,
RA   Griggs A., Gujja S., Heiman D.I., Hepburn T.A., Howarth C., Jen D.,
RA   Larson L., Lewis B., Mehta T., Park D., Pearson M., Roberts A., Saif S.,
RA   Shea T.D., Shenoy N., Sisk P., Stolte C., Sykes S., Walk T., White J.,
RA   Yandava C., Klein B., McEwen J.G., Puccia R., Goldman G.H., Felipe M.S.,
RA   Nino-Vega G., San-Blas G., Taylor J.W., Mendoza L., Galagan J.E.,
RA   Nusbaum C., Birren B.W.;
RT   "The genome sequence of Ajellomyces capsulatus strain H143.";
RL   Submitted (MAY-2009) to the EMBL/GenBank/DDBJ databases.
CC   -!- COFACTOR:
CC       Name=pyruvate; Xref=ChEBI:CHEBI:15361;
CC         Evidence={ECO:0000256|ARBA:ARBA00001928};
CC   -!- PATHWAY: Lipid metabolism. {ECO:0000256|ARBA:ARBA00005189}.
CC   -!- PATHWAY: Phospholipid metabolism; phosphatidylethanolamine
CC       biosynthesis. {ECO:0000256|ARBA:ARBA00024326}.
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DR   EMBL; GG692432; EER38047.1; -; Genomic_DNA.
DR   AlphaFoldDB; C6HNK1; -.
DR   STRING; 544712.C6HNK1; -.
DR   VEuPathDB; FungiDB:HCDG_07782; -.
DR   eggNOG; KOG2420; Eukaryota.
DR   HOGENOM; CLU_029061_1_1_1; -.
DR   OMA; ADSKVHD; -.
DR   UniPathway; UPA00558; -.
DR   Proteomes; UP000002624; Unassembled WGS sequence.
DR   GO; GO:0004609; F:phosphatidylserine decarboxylase activity; IEA:UniProtKB-EC.
DR   GO; GO:0006646; P:phosphatidylethanolamine biosynthetic process; IEA:UniProtKB-UniPathway.
DR   InterPro; IPR003817; PS_Dcarbxylase.
DR   InterPro; IPR033177; PSD-B.
DR   NCBIfam; TIGR00163; PS_decarb; 1.
DR   PANTHER; PTHR10067; PHOSPHATIDYLSERINE DECARBOXYLASE; 1.
DR   PANTHER; PTHR10067:SF6; PHOSPHATIDYLSERINE DECARBOXYLASE PROENZYME, MITOCHONDRIAL; 1.
DR   Pfam; PF02666; PS_Dcarbxylase; 2.
PE   4: Predicted;
KW   Decarboxylase {ECO:0000256|ARBA:ARBA00022793};
KW   Lyase {ECO:0000256|ARBA:ARBA00023239};
KW   Reference proteome {ECO:0000313|Proteomes:UP000002624}.
FT   REGION          46..65
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   402 AA;  44572 MW;  A98E2D4F207EE144 CRC64;
     MFGGRAAIYR NPARFARTWE VVAAELAPCR ASNGITAVSR RRLFSSSSGR WQQNGHGGNG
     SQGKESFRSR LRIALGNTKI KWHPIPVGLG IGFLGFVQFF RSKKSEKERL EREGSEGKAS
     ARRKIRPSGP WQVQVMSTLP LKAMSRLWGR FNELSIPYYL RVPGFKLYSW IFGVNLDEVG
     EPDLHTYPNL AAFFYRELKP GVRPLDPNPL AILSPSDGRI LQFGMIENGE VEQVKGMTYS
     LDALLGHEEF SPGHEAVHPT KAPIHHSVHH ERTSNKVPDN VAADENFAKM NGITYTLPTL
     LSGKGKGASP GDKPLDASMH STTSSEAKVK ADLAKGKTAW YMPTPTSNKS LFYVVIYLAP
     GDYHRFHSPV SWVVESRRHF AGELFSVSPA SSPRPLRWGS SA
//