ID C6HR75_AJECH Unreviewed; 557 AA.
AC C6HR75;
DT 01-SEP-2009, integrated into UniProtKB/TrEMBL.
DT 01-SEP-2009, sequence version 1.
DT 27-MAR-2024, entry version 47.
DE SubName: Full=Type I phosphodiesterase/nucleotide pyrophosphatase {ECO:0000313|EMBL:EER37009.1};
GN ORFNames=HCDG_08460 {ECO:0000313|EMBL:EER37009.1};
OS Ajellomyces capsulatus (strain H143) (Darling's disease fungus)
OS (Histoplasma capsulatum).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Eurotiomycetidae; Onygenales; Ajellomycetaceae; Histoplasma.
OX NCBI_TaxID=544712 {ECO:0000313|EMBL:EER37009.1, ECO:0000313|Proteomes:UP000002624};
RN [1] {ECO:0000313|Proteomes:UP000002624}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=H143 {ECO:0000313|Proteomes:UP000002624};
RA Champion M., Cuomo C.A., Ma L.-J., Henn M.R., Sil A., Goldman B.,
RA Young S.K., Kodira C.D., Zeng Q., Koehrsen M., Alvarado L., Berlin A.M.,
RA Borenstein D., Chen Z., Engels R., Freedman E., Gellesch M., Goldberg J.,
RA Griggs A., Gujja S., Heiman D.I., Hepburn T.A., Howarth C., Jen D.,
RA Larson L., Lewis B., Mehta T., Park D., Pearson M., Roberts A., Saif S.,
RA Shea T.D., Shenoy N., Sisk P., Stolte C., Sykes S., Walk T., White J.,
RA Yandava C., Klein B., McEwen J.G., Puccia R., Goldman G.H., Felipe M.S.,
RA Nino-Vega G., San-Blas G., Taylor J.W., Mendoza L., Galagan J.E.,
RA Nusbaum C., Birren B.W.;
RT "The genome sequence of Ajellomyces capsulatus strain H143.";
RL Submitted (MAY-2009) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; GG692436; EER37009.1; -; Genomic_DNA.
DR AlphaFoldDB; C6HR75; -.
DR STRING; 544712.C6HR75; -.
DR VEuPathDB; FungiDB:HCDG_08460; -.
DR HOGENOM; CLU_017594_4_0_1; -.
DR OMA; INSVDIY; -.
DR Proteomes; UP000002624; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0016740; F:transferase activity; IEA:UniProtKB-KW.
DR GO; GO:0006506; P:GPI anchor biosynthetic process; IEA:UniProtKB-KW.
DR CDD; cd16018; Enpp; 1.
DR Gene3D; 3.30.1360.180; -; 1.
DR Gene3D; 3.40.720.10; Alkaline Phosphatase, subunit A; 1.
DR InterPro; IPR017850; Alkaline_phosphatase_core_sf.
DR InterPro; IPR002591; Phosphodiest/P_Trfase.
DR PANTHER; PTHR10151:SF120; BIS(5'-ADENOSYL)-TRIPHOSPHATASE; 1.
DR PANTHER; PTHR10151; ECTONUCLEOTIDE PYROPHOSPHATASE/PHOSPHODIESTERASE; 1.
DR Pfam; PF01663; Phosphodiest; 1.
DR SUPFAM; SSF53649; Alkaline phosphatase-like; 1.
PE 4: Predicted;
KW GPI-anchor biosynthesis {ECO:0000256|ARBA:ARBA00022502};
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000002624};
KW Transferase {ECO:0000256|ARBA:ARBA00022679};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 12..33
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT REGION 465..486
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 500..531
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 557 AA; 62217 MW; F06D879935EEF4C3 CRC64;
MKSYVPSRGS WCFKVSILST GIVVLFLILY LGAYKESSSF RSARQPRTLL SNGTSLFAPT
TILISLDGFR ADFLNRGLTP ALNSFIANGI SPAYMLPSFP SVTFPNHFTL VTGLYPESHG
IVGNSFWDPV LREDFYYTDP ARSLDPKWWT AEPVWVTAEK QGVRTAIHMW PGSEAHIGNI
EPTYLDKFNA KEDLASKAKR VLSFLDLPGD QEAQDLSSDT DRRPQLIAAY VPHVDSDGHT
FGPNSTEIRS TLARVDEMLA EIFKGLHSRN LTDVVNIVVV SDHGMATTST DRLVQLDDII
DVDLVDRLDG WPLQGIRPKR PEDLEILKQQ LAESSKQYND SIDVYTRETM PDRYHFSSND
RIAPLWVVPK TGWAVVEKST FNVQDAKMKK TVYHPRGLHG YDHEHPLMRA IFVARGPKFP
HHPNSRVENF QNTEVYNIIC DSLEIEAHPN NGTLRLPLNP IGFHSPEDFP SANSPDDPPV
NTGPSSAVIT SKLQITASSN LPTTILNSGS PDPTSTPKHG EKDTSASTSS SSLWDKFLDR
IQWLKNWAQG FLDSVDR
//
