ID   C6HRA4_AJECH            Unreviewed;       249 AA.
AC   C6HRA4;
DT   01-SEP-2009, integrated into UniProtKB/TrEMBL.
DT   01-SEP-2009, sequence version 1.
DT   27-MAR-2024, entry version 48.
DE   SubName: Full=Methyltransferase {ECO:0000313|EMBL:EER37038.1};
GN   ORFNames=HCDG_08489 {ECO:0000313|EMBL:EER37038.1};
OS   Ajellomyces capsulatus (strain H143) (Darling's disease fungus)
OS   (Histoplasma capsulatum).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC   Eurotiomycetidae; Onygenales; Ajellomycetaceae; Histoplasma.
OX   NCBI_TaxID=544712 {ECO:0000313|EMBL:EER37038.1, ECO:0000313|Proteomes:UP000002624};
RN   [1] {ECO:0000313|Proteomes:UP000002624}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=H143 {ECO:0000313|Proteomes:UP000002624};
RA   Champion M., Cuomo C.A., Ma L.-J., Henn M.R., Sil A., Goldman B.,
RA   Young S.K., Kodira C.D., Zeng Q., Koehrsen M., Alvarado L., Berlin A.M.,
RA   Borenstein D., Chen Z., Engels R., Freedman E., Gellesch M., Goldberg J.,
RA   Griggs A., Gujja S., Heiman D.I., Hepburn T.A., Howarth C., Jen D.,
RA   Larson L., Lewis B., Mehta T., Park D., Pearson M., Roberts A., Saif S.,
RA   Shea T.D., Shenoy N., Sisk P., Stolte C., Sykes S., Walk T., White J.,
RA   Yandava C., Klein B., McEwen J.G., Puccia R., Goldman G.H., Felipe M.S.,
RA   Nino-Vega G., San-Blas G., Taylor J.W., Mendoza L., Galagan J.E.,
RA   Nusbaum C., Birren B.W.;
RT   "The genome sequence of Ajellomyces capsulatus strain H143.";
RL   Submitted (MAY-2009) to the EMBL/GenBank/DDBJ databases.
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DR   EMBL; GG692436; EER37038.1; -; Genomic_DNA.
DR   AlphaFoldDB; C6HRA4; -.
DR   STRING; 544712.C6HRA4; -.
DR   VEuPathDB; FungiDB:HCDG_08489; -.
DR   HOGENOM; CLU_052868_3_1_1; -.
DR   OMA; TEGMIHA; -.
DR   Proteomes; UP000002624; Unassembled WGS sequence.
DR   GO; GO:0008168; F:methyltransferase activity; IEA:UniProtKB-KW.
DR   GO; GO:0032259; P:methylation; IEA:UniProtKB-KW.
DR   CDD; cd02440; AdoMet_MTases; 1.
DR   Gene3D; 3.40.50.150; Vaccinia Virus protein VP39; 1.
DR   InterPro; IPR026669; Arsenite_MeTrfase-like.
DR   InterPro; IPR025714; Methyltranfer_dom.
DR   InterPro; IPR029063; SAM-dependent_MTases_sf.
DR   PANTHER; PTHR43675; ARSENITE METHYLTRANSFERASE; 1.
DR   PANTHER; PTHR43675:SF33; ARSENITE METHYLTRANSFERASE; 1.
DR   Pfam; PF13847; Methyltransf_31; 1.
DR   SUPFAM; SSF53335; S-adenosyl-L-methionine-dependent methyltransferases; 1.
PE   4: Predicted;
KW   Methyltransferase {ECO:0000313|EMBL:EER37038.1};
KW   Reference proteome {ECO:0000313|Proteomes:UP000002624};
KW   Transferase {ECO:0000313|EMBL:EER37038.1}.
FT   DOMAIN          63..168
FT                   /note="Methyltransferase"
FT                   /evidence="ECO:0000259|Pfam:PF13847"
SQ   SEQUENCE   249 AA;  26477 MW;  A82579CD08671EAC CRC64;
     MAEPQVYQEV QKHYSSAAKT SDDRYGHDVA TAFGYSKEEL ASIPQDANLG LSCGNPLALA
     QLKEGETVID FGSGAGIDAF LAAKNVGPNG KDMLARANSN KENTGAAAAN VAFVESKITA
     VDLPGAVADC IISNCVVNLV PEAEKQLAFN EMARLLKPGG RVALSDILDV LCRCEERFEH
     IHFSMETPKN ASGGCCGVVK KHEPTPCCGP ALSKEERGPG IFSEGFKAEF ANVDFNEWAG
     SFKIYAVKN
//