ID C6HRA6_AJECH Unreviewed; 302 AA.
AC C6HRA6;
DT 01-SEP-2009, integrated into UniProtKB/TrEMBL.
DT 01-SEP-2009, sequence version 1.
DT 27-MAR-2024, entry version 51.
DE SubName: Full=26S proteasome regulatory subunit {ECO:0000313|EMBL:EER37040.1};
GN ORFNames=HCDG_08491 {ECO:0000313|EMBL:EER37040.1};
OS Ajellomyces capsulatus (strain H143) (Darling's disease fungus)
OS (Histoplasma capsulatum).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Eurotiomycetidae; Onygenales; Ajellomycetaceae; Histoplasma.
OX NCBI_TaxID=544712 {ECO:0000313|EMBL:EER37040.1, ECO:0000313|Proteomes:UP000002624};
RN [1] {ECO:0000313|Proteomes:UP000002624}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=H143 {ECO:0000313|Proteomes:UP000002624};
RA Champion M., Cuomo C.A., Ma L.-J., Henn M.R., Sil A., Goldman B.,
RA Young S.K., Kodira C.D., Zeng Q., Koehrsen M., Alvarado L., Berlin A.M.,
RA Borenstein D., Chen Z., Engels R., Freedman E., Gellesch M., Goldberg J.,
RA Griggs A., Gujja S., Heiman D.I., Hepburn T.A., Howarth C., Jen D.,
RA Larson L., Lewis B., Mehta T., Park D., Pearson M., Roberts A., Saif S.,
RA Shea T.D., Shenoy N., Sisk P., Stolte C., Sykes S., Walk T., White J.,
RA Yandava C., Klein B., McEwen J.G., Puccia R., Goldman G.H., Felipe M.S.,
RA Nino-Vega G., San-Blas G., Taylor J.W., Mendoza L., Galagan J.E.,
RA Nusbaum C., Birren B.W.;
RT "The genome sequence of Ajellomyces capsulatus strain H143.";
RL Submitted (MAY-2009) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the proteasome subunit S5A family.
CC {ECO:0000256|ARBA:ARBA00005574}.
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DR EMBL; GG692436; EER37040.1; -; Genomic_DNA.
DR AlphaFoldDB; C6HRA6; -.
DR STRING; 544712.C6HRA6; -.
DR VEuPathDB; FungiDB:HCDG_08491; -.
DR eggNOG; KOG2884; Eukaryota.
DR HOGENOM; CLU_033293_1_0_1; -.
DR OMA; QMSMQDQ; -.
DR Proteomes; UP000002624; Unassembled WGS sequence.
DR GO; GO:0000502; C:proteasome complex; IEA:UniProtKB-KW.
DR CDD; cd01452; VWA_26S_proteasome_subunit; 1.
DR Gene3D; 1.10.287.3990; -; 1.
DR Gene3D; 3.40.50.410; von Willebrand factor, type A domain; 1.
DR InterPro; IPR003903; UIM_dom.
DR InterPro; IPR002035; VWF_A.
DR InterPro; IPR036465; vWFA_dom_sf.
DR PANTHER; PTHR10223; 26S PROTEASOME NON-ATPASE REGULATORY SUBUNIT 4; 1.
DR PANTHER; PTHR10223:SF0; 26S PROTEASOME NON-ATPASE REGULATORY SUBUNIT 4; 1.
DR Pfam; PF13519; VWA_2; 1.
DR SMART; SM00327; VWA; 1.
DR SUPFAM; SSF53300; vWA-like; 1.
DR PROSITE; PS50330; UIM; 1.
DR PROSITE; PS50234; VWFA; 1.
PE 3: Inferred from homology;
KW Proteasome {ECO:0000256|ARBA:ARBA00022942, ECO:0000313|EMBL:EER37040.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000002624}.
FT DOMAIN 5..189
FT /note="VWFA"
FT /evidence="ECO:0000259|PROSITE:PS50234"
FT REGION 239..302
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 239..257
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 283..302
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 302 AA; 32453 MW; 92ACF1DD1DA69461 CRC64;
MVLEATMIIV DNSESSRNGD YLPTRFEAQA DAINLIHSAK TQANPESSVG LMSMAGKGPE
VLVTLTADIG KILDGLHRTK IRGQAHLASS IQVAGLALKH RRERAQRQRI IVFTCSPIAE
DEKTLIKLAK RMKKYNVSVD FVAFGDLDDD TIKKLEAFNE NVNGADGSHL AVIHPGANLL
SDSLLTTPIL GGDGMGVGRT GGEEGVDDGV DIGFDPSADP ELAFALRMSL EEEQARIEKE
RNEMAEKEKR EKAVLAGIAE GSEETQPLLD KNGEPSGSGS GSNEGKKDDK DKRDNGDKMD
TA
//
