ID C6HUB4_9BACT Unreviewed; 494 AA.
AC C6HUB4;
DT 01-SEP-2009, integrated into UniProtKB/TrEMBL.
DT 01-SEP-2009, sequence version 1.
DT 27-MAR-2024, entry version 21.
DE SubName: Full=HNH endonuclease {ECO:0000313|EMBL:EES53847.1};
GN ORFNames=UBAL3_48660061 {ECO:0000313|EMBL:EES53847.1};
OS Leptospirillum ferrodiazotrophum.
OC Bacteria; Nitrospirota; Nitrospiria; Nitrospirales; Nitrospiraceae;
OC Leptospirillum.
OX NCBI_TaxID=412449 {ECO:0000313|EMBL:EES53847.1, ECO:0000313|Proteomes:UP000009374};
RN [1] {ECO:0000313|EMBL:EES53847.1, ECO:0000313|Proteomes:UP000009374}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=19429552; DOI=10.1128/AEM.02943-08;
RA Goltsman D.S., Denef V.J., Singer S.W., VerBerkmoes N.C., Lefsrud M.,
RA Mueller R.S., Dick G.J., Sun C.L., Wheeler K.E., Zemla A., Baker B.J.,
RA Hauser L., Land M., Shah M.B., Thelen M.P., Hettich R.L., Banfield J.F.;
RT "Community genomic and proteomic analyses of chemoautotrophic iron-
RT oxidizing "Leptospirillum rubarum" (Group II) and "Leptospirillum
RT ferrodiazotrophum" (Group III) bacteria in acid mine drainage biofilms.";
RL Appl. Environ. Microbiol. 75:4599-4615(2009).
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DR EMBL; GG693853; EES53847.1; -; Genomic_DNA.
DR AlphaFoldDB; C6HUB4; -.
DR Proteomes; UP000009374; Unassembled WGS sequence.
DR GO; GO:0004519; F:endonuclease activity; IEA:UniProtKB-KW.
DR GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR CDD; cd00085; HNHc; 1.
DR Gene3D; 1.10.30.50; -; 1.
DR InterPro; IPR002711; HNH.
DR InterPro; IPR003615; HNH_nuc.
DR InterPro; IPR047693; RNA-guided_IscB-like.
DR InterPro; IPR025938; RRXRR_dom.
DR NCBIfam; NF040563; guided_IscB; 1.
DR PANTHER; PTHR33877:SF2; HNH NUCLEASE DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR33877; SLL1193 PROTEIN; 1.
DR Pfam; PF01844; HNH; 1.
DR Pfam; PF14239; RRXRR; 1.
DR SMART; SM00507; HNHc; 1.
PE 4: Predicted;
KW Endonuclease {ECO:0000313|EMBL:EES53847.1};
KW Hydrolase {ECO:0000313|EMBL:EES53847.1};
KW Nuclease {ECO:0000313|EMBL:EES53847.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000009374}.
FT DOMAIN 249..300
FT /note="HNH nuclease"
FT /evidence="ECO:0000259|SMART:SM00507"
FT REGION 1..35
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 494 AA; 55488 MW; 0C53F6CB78723B06 CRC64;
MLPQSRALEA ADADNREGQD ETVGGKGAIP KPVANIPEGR RFARSALRPQ GQCNVRFDEG
FVQVFVLDKK KKPLMPCHPA RARELLREGR AVVHRIAPFT IRLKDRIGGE TQTIRVKLDP
GSKTTGLAVV REEETDGEKT AHVLFQAEIH HRGSAIKKKL DQRRAFRRRR RSQLRYRTPR
FDNRTRPDGW LPPSLRHRVD TTLAWVERLR RLVPVSELSQ ELVRFDMQKI ENPEISGVEY
QQGTLAGYEV REYLLEKWGG TCAYCGSENV PLEIDHIHPR SLGGSDRVSN LTLACRSCNL
KKGNRPVGEF LAKTPERLST ILARAKAPLK DAAAVNATRW VLFQALKATG LPVETASGGR
TKWNRTRLLL PKTHALDAAC VGKVDRIEGW NRPCLSVKAT GRGSYRRTRL DAFGFPRGSL
TRTKAHFGFQ TGDRVMAIVT KGKKNRNLCR TGGSEKLRQF QHPNRLRSGA GDFLQGLSAS
PAGRRVRIFY PSDH
//
