ID C6HVU5_9BACT Unreviewed; 1104 AA.
AC C6HVU5;
DT 01-SEP-2009, integrated into UniProtKB/TrEMBL.
DT 01-SEP-2009, sequence version 1.
DT 27-MAR-2024, entry version 59.
DE SubName: Full=Diguanylate cyclase/phosphodiesterase with PAS/PAC sensor(S) {ECO:0000313|EMBL:EES53274.1};
GN ORFNames=UBAL3_79800008 {ECO:0000313|EMBL:EES53274.1};
OS Leptospirillum ferrodiazotrophum.
OC Bacteria; Nitrospirota; Nitrospiria; Nitrospirales; Nitrospiraceae;
OC Leptospirillum.
OX NCBI_TaxID=412449 {ECO:0000313|EMBL:EES53274.1, ECO:0000313|Proteomes:UP000009374};
RN [1] {ECO:0000313|EMBL:EES53274.1, ECO:0000313|Proteomes:UP000009374}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=19429552; DOI=10.1128/AEM.02943-08;
RA Goltsman D.S., Denef V.J., Singer S.W., VerBerkmoes N.C., Lefsrud M.,
RA Mueller R.S., Dick G.J., Sun C.L., Wheeler K.E., Zemla A., Baker B.J.,
RA Hauser L., Land M., Shah M.B., Thelen M.P., Hettich R.L., Banfield J.F.;
RT "Community genomic and proteomic analyses of chemoautotrophic iron-
RT oxidizing "Leptospirillum rubarum" (Group II) and "Leptospirillum
RT ferrodiazotrophum" (Group III) bacteria in acid mine drainage biofilms.";
RL Appl. Environ. Microbiol. 75:4599-4615(2009).
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DR EMBL; GG693866; EES53274.1; -; Genomic_DNA.
DR AlphaFoldDB; C6HVU5; -.
DR Proteomes; UP000009374; Unassembled WGS sequence.
DR GO; GO:0020037; F:heme binding; IEA:InterPro.
DR GO; GO:0019825; F:oxygen binding; IEA:InterPro.
DR GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR CDD; cd01948; EAL; 1.
DR CDD; cd01949; GGDEF; 1.
DR CDD; cd14759; GS_GGDEF_2; 1.
DR CDD; cd00130; PAS; 1.
DR Gene3D; 3.30.450.40; -; 1.
DR Gene3D; 3.30.70.270; -; 1.
DR Gene3D; 3.20.20.450; EAL domain; 1.
DR Gene3D; 1.10.490.10; Globins; 1.
DR Gene3D; 3.30.450.20; PAS domain; 1.
DR InterPro; IPR001633; EAL_dom.
DR InterPro; IPR035919; EAL_sf.
DR InterPro; IPR003018; GAF.
DR InterPro; IPR029016; GAF-like_dom_sf.
DR InterPro; IPR000160; GGDEF_dom.
DR InterPro; IPR012292; Globin/Proto.
DR InterPro; IPR029787; Nucleotide_cyclase.
DR InterPro; IPR000014; PAS.
DR InterPro; IPR035965; PAS-like_dom_sf.
DR InterPro; IPR013767; PAS_fold.
DR InterPro; IPR043128; Rev_trsase/Diguanyl_cyclase.
DR NCBIfam; TIGR00254; GGDEF; 1.
DR NCBIfam; TIGR00229; sensory_box; 1.
DR PANTHER; PTHR33121; CYCLIC DI-GMP PHOSPHODIESTERASE PDEF; 1.
DR PANTHER; PTHR33121:SF71; CYCLIC DI-GMP PHOSPHODIESTERASE PDEF; 1.
DR Pfam; PF00563; EAL; 1.
DR Pfam; PF01590; GAF; 1.
DR Pfam; PF00990; GGDEF; 1.
DR Pfam; PF00989; PAS; 1.
DR SMART; SM00052; EAL; 1.
DR SMART; SM00267; GGDEF; 1.
DR SUPFAM; SSF141868; EAL domain-like; 1.
DR SUPFAM; SSF55781; GAF domain-like; 1.
DR SUPFAM; SSF55073; Nucleotide cyclase; 1.
DR SUPFAM; SSF55785; PYP-like sensor domain (PAS domain); 1.
DR PROSITE; PS50883; EAL; 1.
DR PROSITE; PS50887; GGDEF; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000009374}.
FT DOMAIN 278..415
FT /note="GGDEF"
FT /evidence="ECO:0000259|PROSITE:PS50887"
FT DOMAIN 755..1007
FT /note="EAL"
FT /evidence="ECO:0000259|PROSITE:PS50883"
FT REGION 1..24
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..17
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1104 AA; 121333 MW; 3740217E114D0D52 CRC64;
MSPSTPNIPP GTPEGAPPDF PNASGGTIFE GCPLPLCLLS PQDTLIAANA AFRALLLAPG
QSPAGQPITV YDTRTETPGE TGETHFRRFD GKLLHVNVQT TRIDFSEQTL RLLALLPLPD
PSGAETPFQQ DYPAGFLSLK GDRTIQASNP AFCRMTAYAA DEIAGISPAI LLEPGESLRK
FERFILQIEE HRNSSETFLF RKKHGEPLFV AIAGTLRNVS PEGSSSIDLV ILDISPLYFS
QKKMEQQLSQ DPMTRLPNRA AFDHAITGAL ARARRKGLVF GVGALDIDDF RPLNETLGKG
TGDRILEELA RRLKTHLRQS DFLARLSGDE FGVIIEELSL ERTVSQVASI LERLHKAVED
PFPLPSGRSL TIGISMGMAL YPSSGEDGES LFREAEAALY QSKASKASRT QWWSMGSILT
SAAALEASFD AYGRESQEIL SRHHDHVKSA ILDFVEAFMA QKDLDPDVRT VLASQDEAGL
QRIVQAQSAH LSFLMAPGRT REEVIARAKR AGEIHALNGV DGAMLAQGMA LYRRLLSERL
SQTVLTARDR YRLILANEIR LQDDLQEELK AATETMSLFF ASLSAPLPEP GALWTDVREK
EISMVGALPG IRCAFLMRLD SQGTFIVESS AGAVGSEAAR IMQDKRFAAT ADPNDPRGQG
LIGHAWRSLE IQRTSNYHSD SRLRYWKEVV HPLGIRSGIS IPIRAADGSA QAVLSLYGAY
PNQFDFHWML QFSRGLAQRW ERLWTLSRAP VSAIPEIRAQ EYRQELFSGG LSMHMQPVVN
LSTGTVVKVE ALARLIRPGG EIIPPGLFLP SLGDAELDRL FREGLDQALG WVARWEEEGV
SLDVSLNLPP GTLRDPGCPV WVEEALSRHG IAPKRLTLEL LENGEIDAKT MDQAIDRLVA
IGVKLSMDDL GSGFSSLQRL VTLPFDSIKV DQGLLKRIRT APLHTISMIG TIVRMGQDFE
RDVVVEGLED RAMVEAAAIL GAPYGQGYSL ARPMPAPQVA QWLRDFRLPI SPGEVTTALG
GLSFHRWIHA ANSDIRRPTL EACPLTRYFS RLGESAAEGA HLHARIHESG PGDSSFKDLT
FWLVEQIRKE QEAFVKGQNS GTEK
//
