ID   C6JP20_FUSVA            Unreviewed;       771 AA.
AC   C6JP20;
DT   01-SEP-2009, integrated into UniProtKB/TrEMBL.
DT   01-SEP-2009, sequence version 1.
DT   27-MAR-2024, entry version 53.
DE   SubName: Full=Phospholipase, patatin family {ECO:0000313|EMBL:EES62768.1};
DE            EC=3.1.1.- {ECO:0000313|EMBL:EES62768.1};
GN   ORFNames=FVAG_00457 {ECO:0000313|EMBL:EES62768.1};
OS   Fusobacterium varium ATCC 27725.
OC   Bacteria; Fusobacteriota; Fusobacteriia; Fusobacteriales; Fusobacteriaceae;
OC   Fusobacterium.
OX   NCBI_TaxID=469618 {ECO:0000313|EMBL:EES62768.1, ECO:0000313|Proteomes:UP000004505};
RN   [1] {ECO:0000313|EMBL:EES62768.1, ECO:0000313|Proteomes:UP000004505}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 27725 {ECO:0000313|EMBL:EES62768.1,
RC   ECO:0000313|Proteomes:UP000004505};
RG   The Broad Institute Genome Sequencing Platform;
RA   Earl A., Ward D., Feldgarden M., Gevers D., Strauss J., Ambrose C.E.,
RA   Allen-Vercoe E., Young S.K., Zeng Q., Gargeya S., Fitzgerald M., Haas B.,
RA   Abouelleil A., Alvarado L., Arachchi H.M., Berlin A., Brown A.,
RA   Chapman S.B., Chen Z., Dunbar C., Freedman E., Gearin G., Gellesch M.,
RA   Goldberg J., Griggs A., Gujja S., Heiman D., Howarth C., Larson L., Lui A.,
RA   MacDonald P.J.P., Mehta T., Montmayeur A., Murphy C., Neiman D.,
RA   Pearson M., Priest M., Roberts A., Saif S., Shea T., Shenoy N., Sisk P.,
RA   Stolte C., Sykes S., Wortman J., Nusbaum C., Birren B.;
RT   "The Genome Sequence of Fusobacterium varium ATCC 27725.";
RL   Submitted (MAY-2011) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:EES62768.1}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; ACIE02000003; EES62768.1; -; Genomic_DNA.
DR   RefSeq; WP_005947542.1; NZ_GL987995.1.
DR   AlphaFoldDB; C6JP20; -.
DR   STRING; 469618.FVAG_00457; -.
DR   GeneID; 77468227; -.
DR   eggNOG; COG0729; Bacteria.
DR   eggNOG; COG1752; Bacteria.
DR   HOGENOM; CLU_014750_2_0_0; -.
DR   Proteomes; UP000004505; Unassembled WGS sequence.
DR   GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-UniRule.
DR   GO; GO:0016042; P:lipid catabolic process; IEA:UniProtKB-UniRule.
DR   CDD; cd07205; Pat_PNPLA6_PNPLA7_NTE1_like; 1.
DR   Gene3D; 3.40.1090.10; Cytosolic phospholipase A2 catalytic domain; 2.
DR   Gene3D; 2.40.160.50; membrane protein fhac: a member of the omp85/tpsb transporter family; 1.
DR   InterPro; IPR016035; Acyl_Trfase/lysoPLipase.
DR   InterPro; IPR043864; Omp85-like_dom.
DR   InterPro; IPR002641; PNPLA_dom.
DR   PANTHER; PTHR14226; NEUROPATHY TARGET ESTERASE/SWISS CHEESE D.MELANOGASTER; 1.
DR   PANTHER; PTHR14226:SF57; SLR0060 PROTEIN; 1.
DR   Pfam; PF19143; Omp85_2; 1.
DR   Pfam; PF01734; Patatin; 1.
DR   SUPFAM; SSF52151; FabD/lysophospholipase-like; 1.
DR   PROSITE; PS51635; PNPLA; 1.
PE   4: Predicted;
KW   Coiled coil {ECO:0000256|SAM:Coils};
KW   Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000313|EMBL:EES62768.1};
KW   Lipid degradation {ECO:0000256|ARBA:ARBA00022963};
KW   Lipid metabolism {ECO:0000256|ARBA:ARBA00023098};
KW   Reference proteome {ECO:0000313|Proteomes:UP000004505}.
FT   DOMAIN          76..267
FT                   /note="PNPLA"
FT                   /evidence="ECO:0000259|PROSITE:PS51635"
FT   COILED          33..67
FT                   /evidence="ECO:0000256|SAM:Coils"
SQ   SEQUENCE   771 AA;  86858 MW;  A9D421970E41494C CRC64;
     MKRKFFLIFT ILFILLIPSK SFSNLKAINN NLTLEEDIEI DKLKAQMKLL EEKIEILEKT
     KAIKLKKNKS KFKIGLALSG GGAKGFAHIG VLKALEEQNI KIDYITGTSM GAVIASLYSA
     GYTPQQIENI LVEINWNGYI SGELDNKKVP LEKKLNSHKY AASVRYDKEF NLSLPKGFGS
     TEMIYLRLKK LLANVEDIND FDKLPIPLRI IATDLNSGKA VALSKGDLAR AITASVAIPT
     ILDPVEIDGN LYVDGLITRN LPVEDVINMG ADIVIASDVG NEVKDNKDYN ILSVMNQLVT
     IQSASSTQHQ REMATILISP DIQSYNATDM KRSREFIALG FEAAQEKIED IKKLPKKEKP
     VKIPTADDNI VIENIVYSEK FSKDKQEILN NLLDKYKNKP LTTEEMEDIM LKLYGIDFIN
     KIYYEFEGTT LVLDADINPA NVFGIGASYA TGYGTTFNIG TELSNVKKLG SSSTIDAQFG
     DYLGLSTHNF FYYGVSNKIG IFANASYKES PLYLYDNTKK IADYTNKSMR FETGILTQYD
     NQLLASYGLA INYSKLEQET GFNWTEQFEY SKNYNEAFFK LSLDRLDGRT RPVSGVKGEL
     NYVWGGTFGA SKSNFYGPLY QFDGYVPINK KFNFSYGFYG GVISGDNILL DQYIKLGGTK
     NNIKNKEFAF YGYEVHQKLV DQFLIGRLGL DYEISTNLYL GTNWNIGTYR EAKEKSDTMD
     KNNNLLWEDY HQGFALSLTY ETMFGPIEFS LSKDNKKGDV VSQFSIGYIF D
//