ID C6LP71_GIAIB Unreviewed; 253 AA.
AC C6LP71;
DT 22-SEP-2009, integrated into UniProtKB/TrEMBL.
DT 22-SEP-2009, sequence version 1.
DT 24-JAN-2024, entry version 53.
DE SubName: Full=DDI1-like DNA-damage inducible protein {ECO:0000313|EMBL:EET02180.1};
GN ORFNames=GL50581_535 {ECO:0000313|EMBL:EET02180.1};
OS Giardia intestinalis (strain ATCC 50581 / GS clone H7) (Giardia lamblia).
OC Eukaryota; Metamonada; Diplomonadida; Hexamitidae; Giardiinae; Giardia.
OX NCBI_TaxID=598745 {ECO:0000313|EMBL:EET02180.1, ECO:0000313|Proteomes:UP000002488};
RN [1] {ECO:0000313|EMBL:EET02180.1, ECO:0000313|Proteomes:UP000002488}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 50581 / GS clone H7 {ECO:0000313|Proteomes:UP000002488};
RX PubMed=19696920; DOI=10.1371/journal.ppat.1000560;
RA Franzen O., Jerlstrom-Hultqvist J., Castro E., Sherwood E., Ankarklev J.,
RA Reiner D.S., Palm D., Andersson J.O., Andersson B., Svard S.G.;
RT "Draft genome sequencing of giardia intestinalis assemblage B isolate GS:
RT is human giardiasis caused by two different species?";
RL PLoS Pathog. 5:E1000560-E1000560(2009).
CC -!- SIMILARITY: Belongs to the DDI1 family.
CC {ECO:0000256|ARBA:ARBA00009136}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EET02180.1}.
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DR EMBL; ACGJ01000686; EET02180.1; -; Genomic_DNA.
DR AlphaFoldDB; C6LP71; -.
DR EnsemblProtists; EET02180; EET02180; GL50581_535.
DR VEuPathDB; GiardiaDB:GL50581_535; -.
DR OMA; YIHIELN; -.
DR OrthoDB; 1332686at2759; -.
DR Proteomes; UP000002488; Unassembled WGS sequence.
DR GO; GO:0004190; F:aspartic-type endopeptidase activity; IEA:InterPro.
DR GO; GO:0006508; P:proteolysis; IEA:InterPro.
DR CDD; cd05479; RP_DDI; 1.
DR Gene3D; 2.40.70.10; Acid Proteases; 1.
DR InterPro; IPR019103; Peptidase_aspartic_DDI1-type.
DR InterPro; IPR021109; Peptidase_aspartic_dom_sf.
DR PANTHER; PTHR12917; ASPARTYL PROTEASE DDI-RELATED; 1.
DR PANTHER; PTHR12917:SF1; AT13091P; 1.
DR Pfam; PF09668; Asp_protease; 1.
DR SUPFAM; SSF50630; Acid proteases; 1.
PE 3: Inferred from homology;
FT DOMAIN 97..219
FT /note="Aspartic peptidase DDI1-type"
FT /evidence="ECO:0000259|Pfam:PF09668"
SQ SEQUENCE 253 AA; 28017 MW; 3FC280C0079E89C6 CRC64;
MPRVTIVYGY RLSTTIETLP DETVLQLIER FMKTCNMPGH AVNAIVRVNG QTLPHDSNCN
NIPPNSTLNY MNPSATFSAP VQKALAREHA NPPAIQRLVD DDIKEVYDHY PELLVNNANS
IYIHIELNGH PDVAVVDTGA EFSTISLETA IQCGLENHID KRQEGRALGV GSSRIVGKIH
LVQLKCGDEY FATNFVVVES VVGTLLGMPF LRMHRMVIDL ANYQIRIGDV SLPIMSDAEV
DAYKADMMGK VNE
//
